Waldenström's macroglobulinemia physical examination: Difference between revisions
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==Overview== | ==Overview== | ||
Patients with Waldenström macroglobulinemia usually appear oriented to time, place, and person. Physical examination of patients with | Patients with Waldenström macroglobulinemia usually appear oriented to time, place, and person. Physical examination of patients with Waldenström's macroglobulinemia is usually remarkable for various findings depending on the degree of tissue infiltration by malignant tumor cells, [[hyperviscosity syndrome]], and accumulation of [[paraprotein]]. | ||
==Physical Examination== | ==Physical Examination== | ||
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*[[Purpura]] | *[[Purpura]] | ||
*[[Raynaud phenomenon]] | *[[Raynaud phenomenon]] | ||
*[[Petechiae]] if platelet count is low | |||
===HEENT=== | ===HEENT=== |
Revision as of 20:19, 3 January 2019
Waldenström's macroglobulinemia Microchapters |
Differentiating Waldenström's macroglobulinemia from other Diseases |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Mirdula Sharma, MBBS [2]
Overview
Patients with Waldenström macroglobulinemia usually appear oriented to time, place, and person. Physical examination of patients with Waldenström's macroglobulinemia is usually remarkable for various findings depending on the degree of tissue infiltration by malignant tumor cells, hyperviscosity syndrome, and accumulation of paraprotein.
Physical Examination
General Appearance
Patients with Waldenström macroglobulinemia are generally well appearing.[1]
Skin
- Purpura
- Raynaud phenomenon
- Petechiae if platelet count is low
HEENT
Neck
Respiratory
- Pleural effusion - in 3-5% of patients
- Rales on auscultation
Cardiovascular system
- Displaced apical impulse
- S3 gallop
Abdomen
Extremity
- Raynaud phenomenon
- Patients may have peripheral edema if disease is complicated by congestive heart failure.
Neuromuscular
- Peripheral neuropathy: distal, symmetric, and sensorimotor[2]
References
- ↑ Waldenström's macroglobulinemia. MedlinePlus (2015) https://www.nlm.nih.gov/medlineplus/ency/article/000588.htm Accessed on November 15th, 2015
- ↑ Coimbra J, Costa AP, Pita F, Rosado P, de Almeida LB (1995). "[Neuropathy in Waldenstrom's macroglobulinemia]". Acta Med Port (in Portuguese). 8 (4): 253–7. PMID 7625222.