Optic neuritis: Difference between revisions
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==Historical Perspective== | ==Historical Perspective== | ||
===Discovery=== | ===Discovery=== | ||
*Optic neuritis was first discovered by von Graefe and Nettleship, in late nineteenth century when [[ophthalmoscopy]] became part of the [[ophthalmic]] examination. | *Optic neuritis was first discovered by von Graefe and Nettleship, in late nineteenth century when [[ophthalmoscopy]] became part of the [[ophthalmic]] examination. | ||
*The association between [ | *The association between [[systemic sclerosis]] and optic neuritis was made by the early 1900's but there was much controversy and misunderstanding about its differential diagnosis, [[pathogenesis]], and possible treatment. | ||
* | *Optic neuritis was first distinguished from [[infectious]], [[hereditary]], [[Toxic optic neuropathy|toxic]], [[Nutritional optic neuropathy|nutritional]], and [[Ischemic optic neuropathy|ischemic optic neuropathie]]<nowiki/>s during the twentieth century. | ||
* | *During late twentieth century, the development of [[Magnetic resonance imaging|MRI]] and the results from recent clinical trials, discovered the relationship between optic neuritis and [[multiple sclerosis]]. | ||
==Outbreaks== | ==Outbreaks== | ||
There have been several outbreaks of [disease name], which are summarized below: | There have been several outbreaks of [disease name], which are summarized below: |
Revision as of 14:48, 2 November 2018
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Mohamadmostafa Jahansouz M.D.[2]
Overview
Historical Perspective
Discovery
- Optic neuritis was first discovered by von Graefe and Nettleship, in late nineteenth century when ophthalmoscopy became part of the ophthalmic examination.
- The association between systemic sclerosis and optic neuritis was made by the early 1900's but there was much controversy and misunderstanding about its differential diagnosis, pathogenesis, and possible treatment.
- Optic neuritis was first distinguished from infectious, hereditary, toxic, nutritional, and ischemic optic neuropathies during the twentieth century.
- During late twentieth century, the development of MRI and the results from recent clinical trials, discovered the relationship between optic neuritis and multiple sclerosis.
Outbreaks
There have been several outbreaks of [disease name], which are summarized below:
Landmark Events in the Development of Treatment Strategies
In [year], [diagnostic test/therapy] was developed by [scientist] to treat/diagnose [disease name].
Classification
Pathophysiology
Causes
Differentiating Optic Neuritis from other Diseases
Epidemiology and Demographics
Optic neuritis typically affects young adults ranging from 18–45 years of age, with a mean age of 30–35 years. There is a strong female predominance. The annual incidence is approximately 5/100,000, with a prevalence estimated to be 115/100,000.[1]