Lymphomatoid granulomatosis classification: Difference between revisions
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== Classification == | == Classification == | ||
Lymphomatoid granulomatosis may be classified according to a grading system which denotes the amount of [[EBV]] positive large B-cell malignant cells that are present. Deciphering the severity of the disease is crucial in determining which treatment options to pursue. The condition is classified into two subtypes:<ref name="pmid23006954">{{cite journal |vauthors=Roschewski M, Wilson WH |title=Lymphomatoid granulomatosis |journal=Cancer J |volume=18 |issue=5 |pages=469–74 |date=2012 |pmid=23006954 |doi=10.1097/PPO.0b013e31826c5e19 |url=}}</ref> | Lymphomatoid granulomatosis may be classified according to a grading system which denotes the amount of [[EBV]] positive large B-cell malignant cells that are present. Deciphering the severity of the disease is crucial in determining which treatment options to pursue. The condition is classified into two subtypes:<ref name="pmid23006954">{{cite journal |vauthors=Roschewski M, Wilson WH |title=Lymphomatoid granulomatosis |journal=Cancer J |volume=18 |issue=5 |pages=469–74 |date=2012 |pmid=23006954 |doi=10.1097/PPO.0b013e31826c5e19 |url=}}</ref> | ||
*Low grade | *Low grade: | ||
**Small amount of large atypical cells | |||
**Few mitotic figures | |||
**Minute amount of necrosis | |||
**Some cases resolve on there own | |||
*High grade | *High grade: | ||
**Preponderant population of large atypical cells | |||
**Profuse necrosis | |||
==References== | ==References== | ||
Revision as of 16:39, 26 November 2018
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Lymphomatoid granulomatosis Microchapters |
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Differentiating Lymphomatoid granulomatosis from other Diseases |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:
Overview
Lymphomatoid granulomatosis may be classified according to a grading system into low grade and high grade.
Classification
Lymphomatoid granulomatosis may be classified according to a grading system which denotes the amount of EBV positive large B-cell malignant cells that are present. Deciphering the severity of the disease is crucial in determining which treatment options to pursue. The condition is classified into two subtypes:[1]
- Low grade:
- Small amount of large atypical cells
- Few mitotic figures
- Minute amount of necrosis
- Some cases resolve on there own
- High grade:
- Preponderant population of large atypical cells
- Profuse necrosis
References
- ↑ Roschewski M, Wilson WH (2012). "Lymphomatoid granulomatosis". Cancer J. 18 (5): 469–74. doi:10.1097/PPO.0b013e31826c5e19. PMID 23006954.