Polycythemia vera history and symptoms: Difference between revisions
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*Fatigue | *Fatigue | ||
*Headache | *Headache | ||
* | *Pruritus | ||
**Especially after exposure to warm water | |||
**May be related to serotonin release by platelets as well as elevated histamine levels | |||
*Abdominal pain | *Abdominal pain | ||
*Loss of concentration | *Loss of concentration | ||
Revision as of 04:49, 7 December 2018
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Mohamad Alkateb, MBBCh [2]; Shyam Patel [3]
Overview
People with polycythemia vera usually asymptomatic. Symptoms of polycythemia vera include headache, fatigue, and pruritis. The symptomatology is highly variable between patients. Some patients can present with a minimal symptom burden that does not result in any change in quality of life, and other patients can have severe symptom burden.
History and Symptoms
Symptoms of polycythemia vera are related to the consequences of excess red blood cells. These symptoms may include:
- Especially after exposure to warm water
- Due to histamine release or prostaglandin production
- Present in approximately 40% of patients
- Tinnitis
- Blurred vision
- Malaise
- Loss of appetite
- Weight loss
- Shortness of breath
- Fatigue
- Dizziness
- Bleeding
- Due to increased susceptibility to infection with H. pylori
History and Symptoms
- The majority of patients with [disease name] are asymptomatic.
OR
- The hallmark of [disease name] is [finding]. A positive history of [finding 1] and [finding 2] is suggestive of [disease name]. The most common symptoms of [disease name] include [symptom 1], [symptom 2], and [symptom 3].
- Symptoms of [disease name] include [symptom 1], [symptom 2], and [symptom 3].
History
Patients with [disease name]] may have a positive history of:
- [History finding 1]
- [History finding 2]
- [History finding 3]
Common Symptoms
Common symptoms of polycythemia vera include:[1]
- Fatigue
- Headache
- Pruritus
- Especially after exposure to warm water
- May be related to serotonin release by platelets as well as elevated histamine levels
- Abdominal pain
- Loss of concentration
- Night sweats
- Sexual problems
- Insomnia
- Decreased mood
- Numbness
- Early satiety
- Dizziness
- Cough
- Bone pains
- Erythromelalgia
- Weakness
Less Common Symptoms
Less common symptoms of polycythemia vera include[1]
- Fever
- Weight loss
- Sweating
- Visual disturbances
- Parasthesias
- Dyspnea
References
- ↑ 1.0 1.1 Stein BL, Oh ST, Berenzon D, Hobbs GS, Kremyanskaya M, Rampal RK, Abboud CN, Adler K, Heaney ML, Jabbour EJ, Komrokji RS, Moliterno AR, Ritchie EK, Rice L, Mascarenhas J, Hoffman R (November 2015). "Polycythemia Vera: An Appraisal of the Biology and Management 10 Years After the Discovery of JAK2 V617F". J. Clin. Oncol. 33 (33): 3953–60. doi:10.1200/JCO.2015.61.6474. PMC 4979103. PMID 26324368.