Myelofibrosis MRI: Difference between revisions
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==Overview== | ==Overview== | ||
MRI may be helpful in the diagnosis of myelofibrosis. Findings on MRI suggestive of myelofibrosis include diffuse decrease in bone marrow signal intensity. | [[Magnetic resonance imaging|MRI]] may be helpful in the [[diagnosis]] of [[myelofibrosis]]. Findings on [[Magnetic resonance imaging|MRI]] suggestive of [[myelofibrosis]] include [[diffuse]] decrease in [[bone marrow]] signal intensity. | ||
==MRI== | ==MRI== | ||
*MRI may be helpful in the diagnosis of myelofibrosis and can be useful in evaluating the stage and the progression of disease. | *[[Magnetic resonance imaging|MRI]] may be helpful in the [[diagnosis]] of [[myelofibrosis]] and can be useful in evaluating the stage and the progression of [[disease]]. | ||
*Findings on MRI suggestive of myelofibrosis include: | *Findings on [[Magnetic resonance imaging|MRI]] suggestive of [[myelofibrosis]] include: | ||
:*Diffuse decrease in bone marrow signal intensity.<ref name=radiomf1>Radiographic features of myelofibrosis. Radswiki. Radiopaedia 2016. http://radiopaedia.org/cases/myelofibrosis-1. Accessed on March 14, 2016</ref><ref name="pmid7972898">{{cite journal |vauthors=Ueda F, Takashima T, Suzuki M, Kadoya M |title=MR diagnosis of myelofibrosis |journal=Radiat Med |volume=12 |issue=3 |pages=135–7 |date=1994 |pmid=7972898 |doi= |url=}}</ref><ref name="pmid3734203">{{cite journal |vauthors=Lanir A, Aghai E, Simon JS, Lee RG, Clouse ME |title=MR imaging in myelofibrosis |journal=J Comput Assist Tomogr |volume=10 |issue=4 |pages=634–6 |date=1986 |pmid=3734203 |doi= |url=}}</ref> | :*[[Diffuse]] decrease in [[bone marrow]] signal intensity.<ref name="radiomf1">Radiographic features of myelofibrosis. Radswiki. Radiopaedia 2016. http://radiopaedia.org/cases/myelofibrosis-1. Accessed on March 14, 2016</ref><ref name="pmid7972898">{{cite journal |vauthors=Ueda F, Takashima T, Suzuki M, Kadoya M |title=MR diagnosis of myelofibrosis |journal=Radiat Med |volume=12 |issue=3 |pages=135–7 |date=1994 |pmid=7972898 |doi= |url=}}</ref><ref name="pmid3734203">{{cite journal |vauthors=Lanir A, Aghai E, Simon JS, Lee RG, Clouse ME |title=MR imaging in myelofibrosis |journal=J Comput Assist Tomogr |volume=10 |issue=4 |pages=634–6 |date=1986 |pmid=3734203 |doi= |url=}}</ref> | ||
:*Very low, mainly homogeneous signal on both T1- and T2-weighted images<ref name="pmid10460376">{{cite journal |vauthors=Guermazi A, de Kerviler E, Cazals-Hatem D, Zagdanski AM, Frija J |title=Imaging findings in patients with myelofibrosis |journal=Eur Radiol |volume=9 |issue=7 |pages=1366–75 |date=1999 |pmid=10460376 |doi=10.1007/s003300050850 |url=}}</ref> | :*Very low, mainly [[Homogenization|homogeneous]] signal on both T1- and T2-weighted images<ref name="pmid10460376">{{cite journal |vauthors=Guermazi A, de Kerviler E, Cazals-Hatem D, Zagdanski AM, Frija J |title=Imaging findings in patients with myelofibrosis |journal=Eur Radiol |volume=9 |issue=7 |pages=1366–75 |date=1999 |pmid=10460376 |doi=10.1007/s003300050850 |url=}}</ref> | ||
:* Foci of extramedullary hematopoiesis involving the spine manifest as heterogeneous and predominantly hyperintense masses | :* Foci of [[Extramedullary hematopoiesis|extramedullary hematopoiesis (EMH)]] involving the [[spine]] manifest as [[heterogeneous]] and predominantly hyperintense [[Mass|masses]] | ||
:*Foci of intracranial extramedullary hematopoiesis manifest as masses of variable signal intensity<ref name="pmid8192010">{{cite journal |vauthors=Koch BL, Bisset GS, Bisset RR, Zimmer MB |title=Intracranial extramedullary hematopoiesis: MR findings with pathologic correlation |journal=AJR Am J Roentgenol |volume=162 |issue=6 |pages=1419–20 |date=June 1994 |pmid=8192010 |doi=10.2214/ajr.162.6.8192010 |url=}}</ref> | :*Foci of [[Cranial|intracranial]] [[Extramedullary hematopoiesis|extramedullary hematopoiesis (EMH)]] manifest as [[Mass|masses]] of variable signal intensity<ref name="pmid8192010">{{cite journal |vauthors=Koch BL, Bisset GS, Bisset RR, Zimmer MB |title=Intracranial extramedullary hematopoiesis: MR findings with pathologic correlation |journal=AJR Am J Roentgenol |volume=162 |issue=6 |pages=1419–20 |date=June 1994 |pmid=8192010 |doi=10.2214/ajr.162.6.8192010 |url=}}</ref> | ||
==Gallery== | ==Gallery== | ||
Revision as of 21:12, 11 December 2018
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Myelofibrosis MRI On the Web |
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American Roentgen Ray Society Images of Myelofibrosis MRI |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Sujit Routray, M.D. [2]
Overview
MRI may be helpful in the diagnosis of myelofibrosis. Findings on MRI suggestive of myelofibrosis include diffuse decrease in bone marrow signal intensity.
MRI
- MRI may be helpful in the diagnosis of myelofibrosis and can be useful in evaluating the stage and the progression of disease.
- Findings on MRI suggestive of myelofibrosis include:
- Diffuse decrease in bone marrow signal intensity.[1][2][3]
- Very low, mainly homogeneous signal on both T1- and T2-weighted images[4]
- Foci of extramedullary hematopoiesis (EMH) involving the spine manifest as heterogeneous and predominantly hyperintense masses
- Foci of intracranial extramedullary hematopoiesis (EMH) manifest as masses of variable signal intensity[5]
Gallery
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![MR images demonstrate diffuse decrease bone marrow signal intensity in this patient with myelofibrosis.[6]](/images/2/2d/Mri_myelofibrosis.jpg)
MR images demonstrate diffuse decrease bone marrow signal intensity in this patient with myelofibrosis.[6]
![MR images demonstrate diffuse decrease bone marrow signal intensity in this patient with myelofibrosis.[6]](/index.php/File:Mri_myelofibrosis.jpg)
References
- ↑ Radiographic features of myelofibrosis. Radswiki. Radiopaedia 2016. http://radiopaedia.org/cases/myelofibrosis-1. Accessed on March 14, 2016
- ↑ Ueda F, Takashima T, Suzuki M, Kadoya M (1994). "MR diagnosis of myelofibrosis". Radiat Med. 12 (3): 135–7. PMID 7972898.
- ↑ Lanir A, Aghai E, Simon JS, Lee RG, Clouse ME (1986). "MR imaging in myelofibrosis". J Comput Assist Tomogr. 10 (4): 634–6. PMID 3734203.
- ↑ Guermazi A, de Kerviler E, Cazals-Hatem D, Zagdanski AM, Frija J (1999). "Imaging findings in patients with myelofibrosis". Eur Radiol. 9 (7): 1366–75. doi:10.1007/s003300050850. PMID 10460376.
- ↑ Koch BL, Bisset GS, Bisset RR, Zimmer MB (June 1994). "Intracranial extramedullary hematopoiesis: MR findings with pathologic correlation". AJR Am J Roentgenol. 162 (6): 1419–20. doi:10.2214/ajr.162.6.8192010. PMID 8192010.
- ↑ Image courtesy of Radswiki. Radiopaedia (original file here). Creative Commons BY-SA-NC