Acute lymphoblastic leukemia echocardiography and ultrasound: Difference between revisions
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==Echocardiograph and ultrasound== | ==Echocardiograph and ultrasound== | ||
* | ===Echocardiograph=== | ||
* | *An echocardiogram is an essential imaging modality in patients with acute lymphoblastic leukemia receiving anthracycline chemotherapy.<ref name="pmid22917553">{{cite journal| author=Neilan TG, Coelho-Filho OR, Pena-Herrera D, Shah RV, Jerosch-Herold M, Francis SA et al.| title=Left ventricular mass in patients with a cardiomyopathy after treatment with anthracyclines. | journal=Am J Cardiol | year= 2012 | volume= 110 | issue= 11 | pages= 1679-86 | pmid=22917553 | doi=10.1016/j.amjcard.2012.07.040 | pmc=3496816 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=22917553 }} </ref> | ||
*Patients who will be receiving anthracycline-based therapy require a baseline echocardiogram to assess the ejection fraction prior to therapy | |||
*Anthracyclines are known to cause cardiac toxicity (specifically cardiomyopathy with cumulative anthracycline doses above 500mg/m2) | |||
*An echocardiogram should be obtained every three months while on therapy with anthracycline. | |||
===Ultrasound=== | |||
*This is useful for diagnosis of lower extremity thrombosis, which commonly occurs in patients with acute lymphoblastic leukemia.<ref name="pmid26973753">{{cite journal| author=Zitek T, Baydoun J, Yepez S, Forred W, Slattery DE| title=Mistakes and Pitfalls Associated with Two-Point Compression Ultrasound for Deep Vein Thrombosis. | journal=West J Emerg Med | year= 2016 | volume= 17 | issue= 2 | pages= 201-8 | pmid=26973753 | doi=10.5811/westjem.2016.1.29335 | pmc=4786247 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=26973753 }} </ref> | |||
*Ultrasound can also assess for splenomegaly, which occurs in patients with acute lymphoblastic leukemia as a result of leukemic infiltration or extramedullary hematopoiesis. | |||
==References== | ==References== | ||
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Shyam Patel [2]
Overview
Additional imaging studies that can be useful in acute lymphoblastic leukemia include echocardiogram and ultrasound. Echocardiogram is useful for assessing cardiac function in patients receiving anthracycline chemotherapy. Ultrasound is useful for assessing for deep vein thrombosis which is a common complication of acute lymphoblastic leukemia. Ultrasound can also assess for spleen size.
Echocardiograph and ultrasound
Echocardiograph
- An echocardiogram is an essential imaging modality in patients with acute lymphoblastic leukemia receiving anthracycline chemotherapy.[1]
- Patients who will be receiving anthracycline-based therapy require a baseline echocardiogram to assess the ejection fraction prior to therapy
- Anthracyclines are known to cause cardiac toxicity (specifically cardiomyopathy with cumulative anthracycline doses above 500mg/m2)
- An echocardiogram should be obtained every three months while on therapy with anthracycline.
Ultrasound
- This is useful for diagnosis of lower extremity thrombosis, which commonly occurs in patients with acute lymphoblastic leukemia.[2]
- Ultrasound can also assess for splenomegaly, which occurs in patients with acute lymphoblastic leukemia as a result of leukemic infiltration or extramedullary hematopoiesis.
References
- ↑ Neilan TG, Coelho-Filho OR, Pena-Herrera D, Shah RV, Jerosch-Herold M, Francis SA; et al. (2012). "Left ventricular mass in patients with a cardiomyopathy after treatment with anthracyclines". Am J Cardiol. 110 (11): 1679–86. doi:10.1016/j.amjcard.2012.07.040. PMC 3496816. PMID 22917553.
- ↑ Zitek T, Baydoun J, Yepez S, Forred W, Slattery DE (2016). "Mistakes and Pitfalls Associated with Two-Point Compression Ultrasound for Deep Vein Thrombosis". West J Emerg Med. 17 (2): 201–8. doi:10.5811/westjem.2016.1.29335. PMC 4786247. PMID 26973753.