Astrocytoma classification: Difference between revisions

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Revision as of 20:48, 27 December 2018

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ammu Susheela, M.D. [2]

Overview

Astrocytoma may be classified according to its histology into 4 grades: pilocytic astrocytoma, diffuse astrocytoma, anaplastic astrocytoma and glioblastoma multiforme.

Classification

Astrocytoma may be classified according to its histology into 4 grades:

Astrocytoma

Pilocyic astrocytoma

Diffuse astrocytoma

Anaplastic astrocytoma

Glioblastomas multiform

Fibrillary astrocytoma

Gemistocytic astrocytoma

Protoplasmic astrocytoma

Oligoastrocytoma

Primary glioblastoma multiforme

Secondary glioblastoma multiforme

Grade 1 — pilocytic astrocytoma
Grade 2 — diffuse astrocytoma
Grade 3 — anaplastic astrocytoma
Grade 4 — glioblastoma multiforme

References

Template:WH Template:WS

@@ Line 5: / Line 5: @@
 Astrocytoma may be classified according to its [[histology]] into 4 grades: [[pilocytic astrocytoma]], [[diffuse astrocytoma]], anaplastic astrocytoma and [[glioblastoma multiforme]].
 ==Classification==
-Astrocytoma may be classified according to presence of [[atypia]], [[mitosis]], endothelial proliferation, and [[necrosis]] into four sybgroups.
+Astrocytoma may be classified according to its histology into 4 grades:
+{{Family tree/start}}
+{{Family tree | | | | | | | | | | | | | | | | | | | | | | | | A01 | | | | | | | | | | | | | | | | | | | A01=Astrocytoma}}
+{{Family tree | | | | | | | | | | | | | | |,|-|-|-|v|-|-|-|-|-|^|-|-|-|-|-|v|-|-|-|.| | | | | | | | | | | | }}
+{{Family tree | | | | | | | | | | | | | | B01 | | B02 | | | | | | | | | | B03 | | B04 | | | | | B01=Pilocyic astrocytoma|B02=Diffuse astrocytoma|B03=Anaplastic astrocytoma|B04=Glioblastomas multiform
+}}
+{{Family tree | | | | | | | | | | | | |,|-|-|-|v|-|^|-|v|-|-|-|.| | | | | | |,|-|-|^|-|-|.| | | | | | | | | }}
+{{Family tree | | | | | | | | | | | | C01 | | C02 | | C03 | | C04 | | | | | C05 | | | | C06 | | | | | | | | C01=Fibrillary astrocytoma|C02=Gemistocytic astrocytoma|C03=Protoplasmic astrocytoma|C04=Oligoastrocytoma|C05=Primary glioblastoma multiforme|C06=Secondary glioblastoma multiforme}}
+{{Family tree | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | }}
+{{Family tree/end}}
 * '''Grade 1''' — [[pilocytic astrocytoma]]
@@ Line 11: / Line 26: @@
 * '''Grade 3''' — anaplastic astrocytoma
 * '''Grade 4''' — [[glioblastoma multiforme]]
-* The WHO-grading scheme is based on the appearance of certain characteristics: [[atypia]], [[mitosis]], endothelial proliferation, and [[necrosis]]. These features reflect the [[malignant]] potential of the [[tumor]] in terms of invasion and growth rate. [[Tumors]] without any of these features are grade I, and those with one of these features (usually atypia) are grade II. [[Tumors]] with 2 criteria and [[tumor]]s with 3 or 4 criteria are WHO grades III and IV, respectively. Thus, the low-grade group of astrocytomas are grades I and II. According to the WHO data the lowest grade astrocytomas (grade I) make up only 2% of recorded astrocytomas, grade II 8%, and the higher grade anaplastic astrocytomas (grade III) 20%. The highest graded astrocytoma (grade IV GBM) is the most common primary [[nervous system neoplasm|nervous system cancer]] and second most frequent [[brain tumor]] after [[brain]] [[metastasis]].  Despite the low incidence of astrocytomas compared to other human [[cancer]]s, mortality is significant, as the higher grades (III & IV) present high mortality rates (mainly due to late detection of the [[neoplasm]]).
 ==See Also==

Astrocytoma classification: Difference between revisions

Revision as of 20:48, 27 December 2018

Overview

Classification

See Also

References

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