Splenic marginal zone lymphoma surgery: Difference between revisions

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The feasibility of surgery depends on the stage of splenic marginal zone lymphoma at diagnosis.  
The feasibility of surgery depends on the stage of splenic marginal zone lymphoma at diagnosis.  
==Surgery==
==Surgery==
* Splenectomy has been performed for the treatment of splenic marginal zone lymphoma (SMZL) over the years with a good success rate and may be delayed until the patient become symptomatic or develop cytopenia.<ref name="pmid12141954">{{cite journal |vauthors=Thieblemont C, Felman P, Berger F, Dumontet C, Arnaud P, Hequet O, Arcache J, Callet-Bauchu E, Salles G, Coiffier B |title=Treatment of splenic marginal zone B-cell lymphoma: an analysis of 81 patients |journal=Clin Lymphoma |volume=3 |issue=1 |pages=41–7 |date=June 2002 |pmid=12141954 |doi= |url=}}</ref>
* Splenectomy has been performed for the treatment of splenic marginal zone lymphoma (SMZL) over the years with a good success rate and may be delayed until the patient become symptomatic or develop cytopenia.<ref name="pmid12141954">{{cite journal |vauthors=Thieblemont C, Felman P, Berger F, Dumontet C, Arnaud P, Hequet O, Arcache J, Callet-Bauchu E, Salles G, Coiffier B |title=Treatment of splenic marginal zone B-cell lymphoma: an analysis of 81 patients |journal=Clin Lymphoma |volume=3 |issue=1 |pages=41–7 |date=June 2002 |pmid=12141954 |doi= |url=}}</ref><ref name="pmid23840125">{{cite journal |vauthors=Wu Z, Zhou J, Wang X, Li YB, Niu T, Peng B |title=Laparoscopic splenectomy for treatment of splenic marginal zone lymphoma |journal=World J. Gastroenterol. |volume=19 |issue=24 |pages=3854–60 |date=June 2013 |pmid=23840125 |pmc=3699034 |doi=10.3748/wjg.v19.i24.3854 |url=}}</ref>
* Splenectomy has been used alone as well as in combination with chemotherapy regime for the treatment but no difference of overall survival benefit was found between the two therapeutic modalities.<ref name="pmid19705496">{{cite journal |vauthors=Milosevic R, Todorovic M, Balint B, Jevtic M, Krstic M, Ristanovic E, Antonijevic N, Pavlovic M, Perunicic M, Petrovic M, Mihaljevic B |title=Splenectomy with chemotherapy vs surgery alone as initial treatment for splenic marginal zone lymphoma |journal=World J. Gastroenterol. |volume=15 |issue=32 |pages=4009–15 |date=August 2009 |pmid=19705496 |pmc=2731951 |doi= |url=}}</ref>
* Splenectomy has been used alone as well as in combination with chemotherapy regime for the treatment but no difference of overall survival benefit was found between the two therapeutic modalities.<ref name="pmid19705496">{{cite journal |vauthors=Milosevic R, Todorovic M, Balint B, Jevtic M, Krstic M, Ristanovic E, Antonijevic N, Pavlovic M, Perunicic M, Petrovic M, Mihaljevic B |title=Splenectomy with chemotherapy vs surgery alone as initial treatment for splenic marginal zone lymphoma |journal=World J. Gastroenterol. |volume=15 |issue=32 |pages=4009–15 |date=August 2009 |pmid=19705496 |pmc=2731951 |doi= |url=}}</ref>



Revision as of 15:57, 31 December 2018

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1], Associate Editor(s)-in-Chief: Sowminya Arikapudi, M.B,B.S. [2]

Overview

The feasibility of surgery depends on the stage of splenic marginal zone lymphoma at diagnosis.

Surgery

  • Splenectomy has been performed for the treatment of splenic marginal zone lymphoma (SMZL) over the years with a good success rate and may be delayed until the patient become symptomatic or develop cytopenia.[1][2]
  • Splenectomy has been used alone as well as in combination with chemotherapy regime for the treatment but no difference of overall survival benefit was found between the two therapeutic modalities.[3]

References

  1. Thieblemont C, Felman P, Berger F, Dumontet C, Arnaud P, Hequet O, Arcache J, Callet-Bauchu E, Salles G, Coiffier B (June 2002). "Treatment of splenic marginal zone B-cell lymphoma: an analysis of 81 patients". Clin Lymphoma. 3 (1): 41–7. PMID 12141954.
  2. Wu Z, Zhou J, Wang X, Li YB, Niu T, Peng B (June 2013). "Laparoscopic splenectomy for treatment of splenic marginal zone lymphoma". World J. Gastroenterol. 19 (24): 3854–60. doi:10.3748/wjg.v19.i24.3854. PMC 3699034. PMID 23840125.
  3. Milosevic R, Todorovic M, Balint B, Jevtic M, Krstic M, Ristanovic E, Antonijevic N, Pavlovic M, Perunicic M, Petrovic M, Mihaljevic B (August 2009). "Splenectomy with chemotherapy vs surgery alone as initial treatment for splenic marginal zone lymphoma". World J. Gastroenterol. 15 (32): 4009–15. PMC 2731951. PMID 19705496.

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