Merkel cell cancer classification: Difference between revisions

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Mercell cell carcinoma is classified into 3 subgroups: trabecular, intermediate, and small cell.
Mercell cell carcinoma is classified into 3 subgroups: trabecular, intermediate, and small cell.
==Classification==
==Classification==
Histologically, MCC has been classified into three distinct subtypes:<ref>{{Cite web | title = Merkel cell carcinoma| url = http://www.merkelcell.org/staging/}}</ref>
Histologically, MCC has been classified into three distinct subtypes:<ref name="pmid3724197">{{cite journal |vauthors=Suster S, Ronnen M, Lin E, Shewach-Millet M |title=Trabecular carcinoma of the skin simulating metastatic disease |journal=J Surg Oncol |volume=32 |issue=2 |pages=73–5 |date=June 1986 |pmid=3724197 |doi= |url=}}</ref>
* '''Trabecular''': classic pattern, large-cell type, high density or granules on ultrasound examination.
* '''Intermediate''': solid pattern (most common).
* '''Small cell''': diffuse, few high density granules on ultrasound examination (second most common).
{| class="wikitable"
{| class="wikitable"
|+
|+
!Subtype
!Subtype
!Pattern
!Pattern
!Anatomical studies
!Histology studies
|-
|-
|'''Trabecular type'''
|'''Trabecular type'''

Revision as of 17:49, 2 January 2019

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Ahmad Al Maradni, M.D. [2]

Overview

Mercell cell carcinoma is classified into 3 subgroups: trabecular, intermediate, and small cell.

Classification

Histologically, MCC has been classified into three distinct subtypes:[1]

Subtype Pattern Histology studies
Trabecular type Classic pattern
  • large-cells
  • High density granules
Intermediate type Solid pattern
  • Most common
Small cell type Diffuse pattern
  • Few high density granules

References

  1. Suster S, Ronnen M, Lin E, Shewach-Millet M (June 1986). "Trabecular carcinoma of the skin simulating metastatic disease". J Surg Oncol. 32 (2): 73–5. PMID 3724197.