Astrocytoma other diagnostic studies: Difference between revisions
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==Other Diagnostic Studies== | ==Other Diagnostic Studies== | ||
Biopsy is helpful in the diagnosis of astrocytomas: | |||
* Astrocytomas are histologically heterogenous | |||
* | * Obtaining small specimen from astrocytomas might lead to false diagnosis. | ||
** | * For lesions with areas of contrast enhancement the specimen should be obtained from those areas. | ||
* | * For lesions with no intra-tumor enhancement the specimen should be obtained from the center of the tumor. | ||
Findings suggestive of/diagnostic of astrocytoma include: | |||
* | *On microscopic histopathological analysis, characteristic findings of astrocytoma is:<ref name=":0">{{cite book | last = Mattle | first = Heinrich | title = Fundamentals of neurology : an illustrated guide | publisher = Thieme | location = Stuttgart New York | year = 2017 | isbn = 9783131364524 }}</ref> | ||
** | **Grade 1: Cells appearance is normal and growth rate is slow. | ||
** | **Grade 2: There might be some atypical cells inside tumor. Mitosis rate is relatively slow. | ||
** | **Grade 3 and 4: Tumor cells are anaplastic and malignant with high mitosis rate. | ||
==References== | ==References== |
Revision as of 16:37, 4 January 2019
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Fahimeh Shojaei, M.D.
Overview
Other Diagnostic Studies
Biopsy is helpful in the diagnosis of astrocytomas:
- Astrocytomas are histologically heterogenous
- Obtaining small specimen from astrocytomas might lead to false diagnosis.
- For lesions with areas of contrast enhancement the specimen should be obtained from those areas.
- For lesions with no intra-tumor enhancement the specimen should be obtained from the center of the tumor.
Findings suggestive of/diagnostic of astrocytoma include:
- On microscopic histopathological analysis, characteristic findings of astrocytoma is:[1]
- Grade 1: Cells appearance is normal and growth rate is slow.
- Grade 2: There might be some atypical cells inside tumor. Mitosis rate is relatively slow.
- Grade 3 and 4: Tumor cells are anaplastic and malignant with high mitosis rate.
References
- ↑ Mattle, Heinrich (2017). Fundamentals of neurology : an illustrated guide. Stuttgart New York: Thieme. ISBN 9783131364524.