Chronic neutrophilic leukemia differential diagnosis: Difference between revisions

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Revision as of 15:59, 22 January 2019

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:

Overview

[Disease name] must be differentiated from other diseases that cause [clinical feature 1], [clinical feature 2], and [clinical feature 3], such as [differential dx1], [differential dx2], and [differential dx3].

OR

[Disease name] must be differentiated from [[differential dx1], [differential dx2], and [differential dx3].

Differentiating [Disease name] from other Diseases

CNL must be differentiated from other diseases that cause neutrophilia such as:

As [disease name] manifests in a variety of clinical forms, differentiation must be established in accordance with the particular subtype. [Subtype name 1] must be differentiated from other diseases that cause [clinical feature 1], such as [differential dx1] and [differential dx2]. In contrast, [subtype name 2] must be differentiated from other diseases that cause [clinical feature 2], such as [differential dx3] and [differential dx4].

Differentiating CNL from other diseases on the basis of neutrophilia:

CNL must be differentiated from other diseases that cause neutrophilia such as:

Neutrophilia/leukemoid reaction

- CML (chronic myeloid leukemia)
- CML-N,(neutrophilic-chronic myelogenous leukemia)
- MPN/MDS (myeloproliferative neoplasms/myelodysplastic syndromes) disorders such as aCML (atypical chronic myeloid leukemia) and CMML (chronic myelomonocytic leukemia)
- Polycythemia vera
- Essential thrombocythemia
- Primary myelofibrosis

	Symptoms			Physical examination			Lab Findings			Imaging			Histopathology
Diseases	Clinical manifestations						Para-clinical findings							Gold standard	Additional findings
	Symptoms			Physical examination			Para-clinical findings
	Symptom 1	Symptom 2	Symptom 3	Physical exam 1	Physical exam 2	Physical exam 3	Lab 1	Lab 2	Lab 3	Imaging 1	Imaging 2	Imaging 3	Histopathology
Differential Diagnosis 1
Differential Diagnosis 2
Differential Diagnosis 3
Diseases	Symptom 1	Symptom 2	Symptom 3	Physical exam 1	Physical exam 2	Physical exam 3	Lab 1	Lab 2	Lab 3	Imaging 1	Imaging 2	Imaging 3	Histopathology	Gold standard	Additional findings
Differential Diagnosis 4
Differential Diagnosis 5
Differential Diagnosis 6

References

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@@ Line 11: / Line 11: @@
 ==Differentiating [Disease name] from other Diseases==
-[Disease name] must be differentiated from other diseases that cause [clinical feature 1], [clinical feature 2], and [clinical feature 3], such as [differential dx1], [differential dx2], and [differential dx3].
+CNL must be differentiated from other diseases that cause neutrophilia such as:
-OR
+As [disease name] manifests in a variety of clinical forms, differentiation must be established in accordance with the particular subtype. [Subtype name 1] must be differentiated from other diseases that cause [clinical feature 1], such as [differential dx1] and [differential dx2]. In contrast, [subtype name 2] must be differentiated from other diseases that cause [clinical feature 2], such as [differential dx3] and [differential dx4].
-[Disease name] must be differentiated from [differential dx1], [differential dx2], and [differential dx3].
-OR
-As [disease name] manifests in a variety of clinical forms, differentiation must be established in accordance with the particular subtype. [Subtype name 1] must be differentiated from other diseases that cause [clinical feature 1], such as [differential dx1] and [differential dx2]. In contrast, [subtype name 2] must be differentiated from other diseases that cause [clinical feature 2], such as [differential dx3] and [differential dx4].
+===Differentiating CNL from other diseases on the basis of neutrophilia:===
-===Differentiating [disease name] from other diseases on the basis of [symptom 1], [symptom 2], and [symptom 3]===
+CNL must be differentiated from other diseases that cause neutrophilia such as:
+* Neutrophilia/leukemoid reaction
-On the basis [symptom 1], [symptom 2], and [symptom 3], [disease name] must be differentiated from [disease 1], [disease 2], [disease 3], [disease 4], [disease 5], and [disease 6].
+** CML (chronic myeloid leukemia)
+** CML-N,(neutrophilic-chronic myelogenous leukemia)
+** MPN/MDS (myeloproliferative neoplasms/myelodysplastic syndromes) disorders such as aCML (atypical chronic myeloid leukemia) and CMML (chronic myelomonocytic leukemia)
+** Polycythemia vera
+** Essential thrombocythemia
+** Primary myelofibrosis
 {|
 |- style="background: #4479BA; color: #FFFFFF; text-align: center;"
-! rowspan="4"  style="background: #4479BA; color: #FFFFFF; text-align: center;|Diseases
+! rowspan="4" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Diseases
-| colspan="6" rowspan="1"  style="background: #4479BA; color: #FFFFFF; text-align: center;|'''Clinical manifestations'''
+| colspan="6" rowspan="1" style="background: #4479BA; color: #FFFFFF; text-align: center;" |'''Clinical manifestations'''
-! colspan="7" rowspan="2"  style="background: #4479BA; color: #FFFFFF; text-align: center;|Para-clinical findings
+! colspan="7" rowspan="2" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Para-clinical findings
-| colspan="1" rowspan="4"  style="background: #4479BA; color: #FFFFFF; text-align: center;|'''Gold standard'''
+| colspan="1" rowspan="4" style="background: #4479BA; color: #FFFFFF; text-align: center;" |'''Gold standard'''
-! rowspan="4" style="background: #4479BA; color: #FFFFFF; text-align: center;|Additional findings
+! rowspan="4" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Additional findings
 |-
-| colspan="3" rowspan="2" style="background: #4479BA; color: #FFFFFF; text-align: center;|'''Symptoms'''
+| colspan="3" rowspan="2" style="background: #4479BA; color: #FFFFFF; text-align: center;" |'''Symptoms'''
-! colspan="3" rowspan="2"  style="background: #4479BA; color: #FFFFFF; text-align: center;|Physical examination
+! colspan="3" rowspan="2" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Physical examination
 |-
-! colspan="3" style="background: #4479BA; color: #FFFFFF; text-align: center;|Lab Findings
+! colspan="3" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Lab Findings
-! colspan="3" style="background: #4479BA; color: #FFFFFF; text-align: center;|Imaging
+! colspan="3" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Imaging
-! rowspan="2" style="background: #4479BA; color: #FFFFFF; text-align: center;|Histopathology
+! rowspan="2" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Histopathology
 |-
-! style="background: #4479BA; color: #FFFFFF; text-align: center;|Symptom 1
+! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Symptom 1
-! colspan="1" rowspan="1" style="background: #4479BA; color: #FFFFFF; text-align: center;|Symptom 2
+! colspan="1" rowspan="1" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Symptom 2
-! style="background: #4479BA; color: #FFFFFF; text-align: center;|Symptom 3
+! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Symptom 3
-! style="background: #4479BA; color: #FFFFFF; text-align: center;|Physical exam 1
+! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Physical exam 1
-! colspan="1" rowspan="1" style="background: #4479BA; color: #FFFFFF; text-align: center;|Physical exam 2
+! colspan="1" rowspan="1" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Physical exam 2
-! style="background: #4479BA; color: #FFFFFF; text-align: center;|Physical exam 3
+! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Physical exam 3
-! style="background: #4479BA; color: #FFFFFF; text-align: center;|Lab 1
+! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Lab 1
-! style="background: #4479BA; color: #FFFFFF; text-align: center;|Lab 2
+! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Lab 2
-! style="background: #4479BA; color: #FFFFFF; text-align: center;|Lab 3
+! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Lab 3
-! style="background: #4479BA; color: #FFFFFF; text-align: center;|Imaging 1
+! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Imaging 1
-! style="background: #4479BA; color: #FFFFFF; text-align: center;|Imaging 2
+! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Imaging 2
-! style="background: #4479BA; color: #FFFFFF; text-align: center;|Imaging 3
+! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Imaging 3
 |-
 | style="background: #DCDCDC; padding: 5px; text-align: center;" |Differential Diagnosis 1