Breast lumps differential diagnosis: Difference between revisions

	Breast lumps Microchapters
Home
Patient Information
Overview
Historical Perspective
Classification
Pathophysiology
Causes
Differentiating Breast lumps from other Diseases
Epidemiology and Demographics
Risk Factors
Screening
Natural History, Complications and Prognosis
Diagnosis
Diagnostic Study of Choice
History and Symptoms
Physical Examination
Laboratory Findings
Electrocardiogram
X-ray
CT
MRI
Ultrasound
Other Imaging Findings
Other Diagnostic Studies
Treatment
Medical Therapy
Surgery
Primary Prevention
Secondary Prevention
Cost-Effectiveness of Therapy
Future or Investigational Therapies
Case Studies
Case #1
Breast lumps differential diagnosis On the Web
Most recent articles
Most cited articles
Review articles
CME Programs
Powerpoint slides
Images
American Roentgen Ray Society Images of Breast lumps differential diagnosis All Images X-rays Echo & Ultrasound CT Images MRI
Ongoing Trials at Clinical Trials.gov
US National Guidelines Clearinghouse
NICE Guidance
FDA on Breast lumps differential diagnosis
on Breast lumps differential diagnosis
Breast lumps differential diagnosis in the news
Blogs on Breast lumps differential diagnosis
Directions to Hospitals Treating Breast lumps
Risk calculators and risk factors for Breast lumps differential diagnosis

← Older edit Newer edit →

VisualWikitext

Revision as of 17:03, 12 January 2019

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Shadan Mehraban, M.D.[2]

Overview

Breast lumps must be differentiated from other diseases such as malignancy, cysts, inflammation and non-inflammatory solid lumps.

Breast symptoms such as nipple discharge and mastalgia require assessment as well ^[1].

Differentiating Breast lumps from other Diseases

Differential diagnosis of breast lumps include: ^[1]

Malignancy or breast cancer
- Associated with following factors^[2]:
  - Geographical area
  - Age
  - Ethnicity
  - Positive family history
  - Pathology results such as:
    - Atypical ductal hyperplasia (ADH)
    - Atypical lobular hyperplasia (ALH)
    - Lobular carcinoma in situ (LCIS)
  - Previous history of radiotherapy
Inflammatory lumps:^[3]^[4]
- Associated to personal habit and disease pattern:
  - Infective lumps
    - Lactational mastitis or abscess
    - Non-lactational mastitis
      - Periductal mastitis in chronic smokers
      - Lobular mastitis in tuberculosis and parasitic infection
  - Non-infective lumps such as chronic granulomatous infection
Solid non-inflammatory lumps ^[5] ^[6]
- Related to age, geographical area and ethnicity
- Mostly fibroadenomas in women aged 20-30 years
- Phyllodes tumor are prevalent in various centers, racial groups in different frequencies
Cysts^[7]
- Related to age and usage of hormonal replacement therapy
- Symptomatic cysts are often seen in women age 30 years to early 50 years
- If menopausaed women may be present due to hormone replacement therapy (HRT)

Differential diagnosis of breast lumps
Benign	Palpable breast masses in women between 20 to 50 years old^[8]The most common types of benign breast lumps are^[9]: Fibroadenoma Cysts Fibrocystic changes Galactocele Fat necrosis Breast abscess
Malignant	The most common types are infiltrating ductal breast carcinoma, infiltrating lobular breast carcinoma, mixed of ductal and lobular carcinoma and usually present as a hard mass in breast^[10]

Differentiating Breast lumps from other Diseases

Diseases			Clinical manifestation									Paraclinical findings
			Demography	History	Symptoms			Signs				Paraclinical findings
	Benign	Malignant	Demography	History	Mass	Pain	Nipple discharge	Breast exam	Skin changes	LAP	Others	Lab findings	Histopathology	Imaging
Fibroadenoma
Breast cyst
Fibrocystic change
Galactocele

Cysts of montgomery
Breast adenoma
Hamartoma
Hemangioma
Breast abscess
Mastitis
Breast carcinoma
Ductal carcinoma in situ
Microinvasive breast cancer
Breast sarcoma
Paget disease
Phyllodes tumor
Lymphoma
Metastasis


Duct ectasia
Intraductal papilloma
Lipoma
Neurofibroma
Pregnancy
Gynecomastia
Premenstrual syndrome
Breast trauma
Fat necrosis
Drugs

References

↑ ^1.0 ^1.1 Cheung KL, Lam TP (2005). "Approach to a lump in the breast: a regional perspective". Asian J Surg. 28 (1): 65–70. doi:10.1016/S1015-9584(09)60264-5. PMID 15691804.
↑ Collyar DE (2001). "Breast cancer: a global perspective". J Clin Oncol. 19 (18 Suppl): 101S–105S. PMID 11560983.
↑ Lang AP, Luchsinger IS, Rawling EG (1987). "Filariasis of the breast". Arch Pathol Lab Med. 111 (8): 757–9. PMID 3307689.
↑ Varghese R, Raghuveer CV, Pai MR, Bansal R (1996). "Microfilariae in cytologic smears: a report of six cases". Acta Cytol. 40 (2): 299–301. doi:10.1159/000333755. PMID 8629415.
↑ Alagaratnam, T.T. & Wong, J. World J. Surg. (1989) 13: 743. https://doi.org/10.1007/BF01658425
↑ Shukla HS, Kumar S (1989). "Benign breast disorders in nonwestern populations: Part II--Benign breast disorders in India". World J Surg. 13 (6): 746–9. PMID 2623884.
↑ Leung TN, Haines CJ, Chung TK (2001). "Five-year compliance with hormone replacement therapy in postmenopausal Chinese women in Hong Kong". Maturitas. 39 (3): 195–201. PMID 11574178.
↑ Elmore JG, Barton MB, Moceri VM, Polk S, Arena PJ, Fletcher SW (1998). "Ten-year risk of false positive screening mammograms and clinical breast examinations". N Engl J Med. 338 (16): 1089–96. doi:10.1056/NEJM199804163381601. PMID 9545356.
↑ Morrow M (2000). "The evaluation of common breast problems". Am Fam Physician. 61 (8): 2371–8, 2385. PMID 10794579.
↑ Schoonjans JM, Brem RF (2001). "Fourteen-gauge ultrasonographically guided large-core needle biopsy of breast masses". J Ultrasound Med. 20 (9): 967–72. PMID 11549157.

Template:WH Template:WS

[pmid15691804-1] 1.0 ^1.1 Cheung KL, Lam TP (2005). "Approach to a lump in the breast: a regional perspective". Asian J Surg. 28 (1): 65–70. doi:10.1016/S1015-9584(09)60264-5. PMID 15691804.

[pmid11560983-2] Collyar DE (2001). "Breast cancer: a global perspective". J Clin Oncol. 19 (18 Suppl): 101S–105S. PMID 11560983.

[pmid3307689-3] Lang AP, Luchsinger IS, Rawling EG (1987). "Filariasis of the breast". Arch Pathol Lab Med. 111 (8): 757–9. PMID 3307689.

[pmid8629415-4] Varghese R, Raghuveer CV, Pai MR, Bansal R (1996). "Microfilariae in cytologic smears: a report of six cases". Acta Cytol. 40 (2): 299–301. doi:10.1159/000333755. PMID 8629415.

[5] Alagaratnam, T.T. & Wong, J. World J. Surg. (1989) 13: 743. https://doi.org/10.1007/BF01658425

[pmid2623884-6] Shukla HS, Kumar S (1989). "Benign breast disorders in nonwestern populations: Part II--Benign breast disorders in India". World J Surg. 13 (6): 746–9. PMID 2623884.

[pmid11574178-7] Leung TN, Haines CJ, Chung TK (2001). "Five-year compliance with hormone replacement therapy in postmenopausal Chinese women in Hong Kong". Maturitas. 39 (3): 195–201. PMID 11574178.

[pmid9545356-8] Elmore JG, Barton MB, Moceri VM, Polk S, Arena PJ, Fletcher SW (1998). "Ten-year risk of false positive screening mammograms and clinical breast examinations". N Engl J Med. 338 (16): 1089–96. doi:10.1056/NEJM199804163381601. PMID 9545356.

[pmid10794579-9] Morrow M (2000). "The evaluation of common breast problems". Am Fam Physician. 61 (8): 2371–8, 2385. PMID 10794579.

[pmid115491572-10] Schoonjans JM, Brem RF (2001). "Fourteen-gauge ultrasonographically guided large-core needle biopsy of breast masses". J Ultrasound Med. 20 (9): 967–72. PMID 11549157.

[1]

[2]

[3]

[4]

[5]

[6]

[7]

[8]

[9]

[10]

@@ Line 60: / Line 60: @@
 !
 ! colspan="9" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Clinical manifestation
-! colspan="4" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Paraclinical findings
+! colspan="3" rowspan="2" |Paraclinical findings
 ! rowspan="3" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Gold standard diagnosis
 ! rowspan="3" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Associated findings
@@ Line 70: / Line 70: @@
 ! colspan="3" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Symptoms
 ! colspan="4" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Signs
-! colspan="3" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Lab findings
-! rowspan="2" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Imaging
 |-
 !Benign
@@ Line 82: / Line 80: @@
 ! style="background: #4479BA; color: #FFFFFF; text-align: center;" |LAP
 ! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Others
-! style="background: #4479BA; color: #FFFFFF; text-align: center;" |
+! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Lab findings
-! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Finding 2
 ! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Histopathology
+!Imaging
 |-
 ! style="background: #4479BA; color: #FFFFFF; text-align: center;" |
@@ Line 98: / Line 96: @@
 | align="center" style="background:#F5F5F5;" |
 |
-| align="center" style="background:#F5F5F5;" |
 | align="center" style="background:#F5F5F5;" |
 | align="center" style="background:#F5F5F5;" |
@@ Line 119: / Line 116: @@
 | align="center" style="background:#F5F5F5;" |
 |
-| align="center" style="background:#F5F5F5;" |
 | align="center" style="background:#F5F5F5;" |
 | align="center" style="background:#F5F5F5;" |
@@ Line 130: / Line 126: @@
 !
 !Fibrocystic change
-!
 !
 !
@@ Line 161: / Line 156: @@
 | align="center" style="background:#F5F5F5;" |
 |
-| align="center" style="background:#F5F5F5;" |
 | align="center" style="background:#F5F5F5;" |
 | align="center" style="background:#F5F5F5;" |
@@ Line 170: / Line 164: @@
 | align="center" style="background:#F5F5F5;" |
 |-
-!
 !
 !
@@ Line 193: / Line 186: @@
 !
 !Cysts of montgomery
-!
 !
 !
@@ Line 214: / Line 206: @@
 !
 ![[Fibroadenoma|Breast adenoma]]
-!
 !
 !
@@ Line 235: / Line 226: @@
 !
 ![[Hamartoma]]
-!
 !
 !
@@ Line 256: / Line 246: @@
 !
 ![[Hemangioma]]
-!
 !
 !
@@ Line 287: / Line 276: @@
 | align="center" style="background:#F5F5F5;" |
 |
-| align="center" style="background:#F5F5F5;" |
 | align="center" style="background:#F5F5F5;" |
 | align="center" style="background:#F5F5F5;" |
@@ Line 298: / Line 286: @@
 !
 !Mastitis
-!
 !
 !
@@ Line 319: / Line 306: @@
 !
 !Breast carcinoma
-!
 !
 !
@@ Line 340: / Line 326: @@
 !
 !Ductal carcinoma in situ
-!
 !
 !
@@ Line 361: / Line 346: @@
 !
 !'''Microinvasive breast cancer'''
-!
 !
 !
@@ Line 382: / Line 366: @@
 !
 !Breast sarcoma
-!
 !
 !
@@ Line 403: / Line 386: @@
 !
 !Paget disease
-!
 !
 !
@@ Line 424: / Line 406: @@
 !
 ![[Phyllodes tumor]]
-!
 !
 !
@@ Line 445: / Line 426: @@
 !
 !Lymphoma
-!
 !
 !
@@ Line 466: / Line 446: @@
 !
 !Metastasis
-!
 !
 !
@@ Line 485: / Line 464: @@
 !
 |-
-!
 !
 !
@@ Line 506: / Line 484: @@
 !
 |-
-!
 !
 !
@@ Line 529: / Line 506: @@
 !
 !Duct ectasia
-!
 !
 !
@@ Line 550: / Line 526: @@
 !
 !Intraductal [[papilloma]]
-!
 !
 !
@@ Line 571: / Line 546: @@
 !
 !Lipoma
-!
 !
 !
@@ Line 592: / Line 566: @@
 !
 ![[Neurofibroma]]
-!
 !
 !
@@ Line 613: / Line 586: @@
 !
 !Pregnancy
-!
 !
 !
@@ Line 634: / Line 606: @@
 !
 !Gynecomastia
-!
 !
 !
@@ Line 655: / Line 626: @@
 !
 !Premenstrual syndrome
-!
 !
 !
@@ Line 676: / Line 646: @@
 !
 !Breast trauma
-!
 !
 !
@@ Line 697: / Line 666: @@
 !
 !Fat necrosis
-!
 !
 !
@@ Line 718: / Line 686: @@
 !
 !Drugs
-!
 !
 !

Breast lumps differential diagnosis: Difference between revisions

Revision as of 17:03, 12 January 2019

Overview

Differentiating Breast lumps from other Diseases

Differentiating Breast lumps from other Diseases

References

Navigation menu

Search