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===Landmark Events in the Development of Treatment Strategies=== | ===Landmark Events in the Development of Treatment Strategies=== | ||
*Genetic studies revolutionized cancer treatment. | |||
* Traditionally appandiceal cancers were approached the same as colorectal cancers. Recent genetic studies demonstrated that appendiceal tumors are Gene profile <ref name="pmid22342786">{{cite journal| author=Levine EA, Blazer DG, Kim MK, Shen P, Stewart JH, Guy C et al.| title=Gene expression profiling of peritoneal metastases from appendiceal and colon cancer demonstrates unique biologic signatures and predicts patient outcomes. | journal=J Am Coll Surg | year= 2012 | volume= 214 | issue= 4 | pages= 599-606; discussion 606-7 | pmid=22342786 | doi=10.1016/j.jamcollsurg.2011.12.028 | pmc=3768122 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=22342786 }} </ref> | |||
*prognosis | |||
<ref name="pmid26821970">{{cite journal| author=Levine EA, Votanopoulos KI, Qasem SA, Philip J, Cummins KA, Chou JW et al.| title=Prognostic Molecular Subtypes of Low-Grade Cancer of the Appendix. | journal=J Am Coll Surg | year= 2016 | volume= 222 | issue= 4 | pages= 493-503 | pmid=26821970 | doi=10.1016/j.jamcollsurg.2015.12.012 | pmc=4808611 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=26821970 }} </ref> | |||
===Famous Cases=== | ===Famous Cases=== | ||
The following are a few famous cases of appendix cancer: | The following are a few famous cases of appendix cancer: | ||
Revision as of 17:52, 15 January 2019
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Soroush Seifirad, M.D.[2]
Overview
Historical Perspective
- Appendix cancer was first described in the published literature by Sir George Thos. Beatson, an English surgeon, in 1913.[1]
Landmark Events in the Development of Treatment Strategies
- Genetic studies revolutionized cancer treatment.
- Traditionally appandiceal cancers were approached the same as colorectal cancers. Recent genetic studies demonstrated that appendiceal tumors are Gene profile [2]
- prognosis
Famous Cases
The following are a few famous cases of appendix cancer:
- Celebrated actress, Audrey Hepburn was the most famous victims of appendix cancer, she passed away in 1993.[4]
- Stuart Scott, ESPN sportscast anchor was diagnosed with appendix cancer in 2007 and died 8 years later in 2015.[5]
References
- ↑ Beatson GT (1913) Note on a Case of Carcinoma of the Vermiform Appendix in a Girl, Aged 20 Years. Glasgow Med J 80 (6):418-422. PMID: 30435413
- ↑ Levine EA, Blazer DG, Kim MK, Shen P, Stewart JH, Guy C; et al. (2012). "Gene expression profiling of peritoneal metastases from appendiceal and colon cancer demonstrates unique biologic signatures and predicts patient outcomes". J Am Coll Surg. 214 (4): 599–606, discussion 606-7. doi:10.1016/j.jamcollsurg.2011.12.028. PMC 3768122. PMID 22342786.
- ↑ Levine EA, Votanopoulos KI, Qasem SA, Philip J, Cummins KA, Chou JW; et al. (2016). "Prognostic Molecular Subtypes of Low-Grade Cancer of the Appendix". J Am Coll Surg. 222 (4): 493–503. doi:10.1016/j.jamcollsurg.2015.12.012. PMC 4808611. PMID 26821970.
- ↑ "Audrey Hepburn Appendix Cancer".
- ↑ "Stuart Scott's Battle With Cancer".
- ↑ "Stuart Scott, ESPN's Voice of Exuberance, Dies at 49 - The New York Times".