Merkel cell cancer history and symptoms: Difference between revisions
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=== History === | === History === | ||
Patients with [[merkel cell carcinoma]] may have a positive history of: | Patients with [[merkel cell carcinoma]] may have a positive history of: | ||
* Severe sun exposure | * Severe [[sun exposure]] | ||
* Organ transplantation | * [[Organ transplant|Organ transplantation]] | ||
* Viral infection like | * Viral infection like | ||
** MCPvY | ** MCPvY | ||
** HIV | ** [[Human Immunodeficiency Virus (HIV)|HIV]] | ||
* Taking immunosuppressive medications | * Taking [[Immunosuppression|immunosuppressive]] medications | ||
* | * | ||
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=== Common Symptoms === | === Common Symptoms === | ||
Common symptoms of [[merkel cell carcinoma]] include | Common symptoms of [[merkel cell carcinoma]] include<ref name="pmid18280333">{{cite journal |vauthors=Heath M, Jaimes N, Lemos B, Mostaghimi A, Wang LC, Peñas PF, Nghiem P |title=Clinical characteristics of Merkel cell carcinoma at diagnosis in 195 patients: the AEIOU features |journal=J. Am. Acad. Dermatol. |volume=58 |issue=3 |pages=375–81 |date=March 2008 |pmid=18280333 |pmc=2335370 |doi=10.1016/j.jaad.2007.11.020 |url=}}</ref> | ||
* Rapid growing, painless and small mass that typically located on a sun exposed area of the body | * Rapid growing, painless and small [[mass]] that typically located on a sun exposed area of the body | ||
* The most common location of [[merkel cell carcinoma]] is the periorbital region on the face | * The most common location of [[merkel cell carcinoma]] is the periorbital region on the face | ||
* The lesions in [[merkel cell carcinoma]] appear as plaques or violaceous solitary and dome-shaped nodules | * The lesions in [[merkel cell carcinoma]] appear as [[plaques]] or violaceous [[solitary]] and dome-shaped nodules | ||
* The nodules in [[merkel cell carcinoma]] appear as red or deep purple in colour | * The nodules in [[merkel cell carcinoma]] appear as red or deep purple in colour | ||
* The most important features in [[merkel cell carcinoma]] can be summarized in an acronym: '''AEIOU''' | |||
** '''A'''-'''[[Asymptomatic]]''' | |||
** '''E- Expanding rapidly''' | |||
** '''I- [[Immunosuppression|Immune suppression]]''' | |||
** '''O- Older than 50 years''' | |||
** '''U- [[Ultraviolet]]-exposure''' | |||
* | * | ||
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Ahmad Al Maradni, M.D. [2]
Overview
Patients with merkel cell carcinoma usually present with a rapid growing, painless, small mass that is typically located on sun exposed area of the body.
History and Symptoms
- The majority of patients with merkel cell carcinoma are asymptomatic almost 88 percent.
History
Patients with merkel cell carcinoma may have a positive history of:
- Severe sun exposure
- Organ transplantation
- Viral infection like
- MCPvY
- HIV
- Taking immunosuppressive medications
Common Symptoms
Common symptoms of merkel cell carcinoma include[1]
- Rapid growing, painless and small mass that typically located on a sun exposed area of the body
- The most common location of merkel cell carcinoma is the periorbital region on the face
- The lesions in merkel cell carcinoma appear as plaques or violaceous solitary and dome-shaped nodules
- The nodules in merkel cell carcinoma appear as red or deep purple in colour
- The most important features in merkel cell carcinoma can be summarized in an acronym: AEIOU
- A-Asymptomatic
- E- Expanding rapidly
- I- Immune suppression
- O- Older than 50 years
- U- Ultraviolet-exposure
References
- ↑ Heath M, Jaimes N, Lemos B, Mostaghimi A, Wang LC, Peñas PF, Nghiem P (March 2008). "Clinical characteristics of Merkel cell carcinoma at diagnosis in 195 patients: the AEIOU features". J. Am. Acad. Dermatol. 58 (3): 375–81. doi:10.1016/j.jaad.2007.11.020. PMC 2335370. PMID 18280333.