Fibroadenoma other diagnostic studies: Difference between revisions
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===Aspiration Cytology=== | ===Aspiration Cytology=== | ||
* The definitive diagnosis of fibroadenoma is confirmed by an ultrasound guided [[biopsy]]. Characteristic findings for fibroadenoma on microscopic histopathological analysis can be found [[Fibroadenoma pathophysiology|'''here''']].<ref name="radio">Fibroadenoma. Radiopaedia (2015) http://radiopaedia.org/articles/fibroadenoma-of-the-breast-1 Accessed on January, 29 2016</ref> | * The definitive diagnosis of fibroadenoma is confirmed by an ultrasound guided [[biopsy]]. Characteristic findings for fibroadenoma on microscopic histopathological analysis can be found [[Fibroadenoma pathophysiology|'''here''']].<ref name="radio">Fibroadenoma. Radiopaedia (2015) http://radiopaedia.org/articles/fibroadenoma-of-the-breast-1 Accessed on January, 29 2016</ref> | ||
* In combination with clinical diagnosis of fibroadenoma, fine needle aspiration (FNA) can improve the sensitivity of the diagnosis to 86%, with a specificity of 76%.<ref name="pmid9754521">{{cite journal |vauthors=Greenberg R, Skornick Y, Kaplan O |title=Management of breast fibroadenomas |journal=J Gen Intern Med |volume=13 |issue=9 |pages=640–5 |date=September 1998 |pmid=9754521 |pmc=1497021 |doi= |url=}}</ref> | |||
* Indications for an ultrasound guided biopsy include: | * Indications for an ultrasound guided biopsy include: | ||
:* Rapidly enlarging mass | :* Rapidly enlarging mass | ||
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Haytham Allaham, M.D. [2]
Overview
The definitive diagnosis of fibroadenoma is confirmed by an ultrasound guided biopsy. Characteristic findings for fibroadenoma on microscopic histopathological analysis can be found here.[1]
Other Diagnostic Studies
Aspiration Cytology
- The definitive diagnosis of fibroadenoma is confirmed by an ultrasound guided biopsy. Characteristic findings for fibroadenoma on microscopic histopathological analysis can be found here.[1]
- In combination with clinical diagnosis of fibroadenoma, fine needle aspiration (FNA) can improve the sensitivity of the diagnosis to 86%, with a specificity of 76%.[2]
- Indications for an ultrasound guided biopsy include:
- Rapidly enlarging mass
- Atypical findings on ultrasound
- A lesion greater than 2.5 cm in size, with no previous studies for comparison
- Patients preference
- The characteristic cytologic features of fibroadenomas include:[2]
- Clusters of spindle cells without inflammatory or fat cells. This is found in 96% of all fibroadenomas.
- Aggregates of cells with a papillary configuration resembling elk antler (antler horn clusters). Found in about 93%.
- Uniform cells with well-defined cytoplasm lying in rows and columns (honeycomb sheets). Found in about 95%
References
- ↑ 1.0 1.1 Fibroadenoma. Radiopaedia (2015) http://radiopaedia.org/articles/fibroadenoma-of-the-breast-1 Accessed on January, 29 2016
- ↑ 2.0 2.1 Greenberg R, Skornick Y, Kaplan O (September 1998). "Management of breast fibroadenomas". J Gen Intern Med. 13 (9): 640–5. PMC 1497021. PMID 9754521.