Acute lymphoblastic leukemia history and symptoms: Difference between revisions
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* [[Dyspnea]] | * [[Dyspnea]] | ||
===Less common symptoms | ===Less common symptoms=== | ||
* [[Bruising|Excessive bruising]] | * [[Bruising|Excessive bruising]] | ||
* [[Petechiae]] | * [[Petechiae]] | ||
Revision as of 20:23, 29 January 2019
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Raviteja Guddeti, M.B.B.S. [2] Carlos A Lopez, M.D. [3]
Overview
Symptoms of acute lymphoblastic leukemia include generalised weakness and fatigue, frequent or unexplained fever and infections, weight loss and/or loss of appetite, excessive bruising, bleeding from wounds, nosebleeds, petechiae, bone pain, joint pains and dyspnea.
History
Patients with Acute lymphoblastic leukemia may have a positive history of:
- Infection
- Bleeding
- Anemia
Common symptoms
Common symptoms of acute lymphoblastic leukemia include the following:[1][2][3][4][5]
- Generalised weakness and fatigue
- Anemia
- Frequent or unexplained fever and infections
- Weight loss
- Anorexia
- Excessive bleeding from minor wounds
- Bone pain
- Dyspnea
Less common symptoms
- Excessive bruising
- Petechiae
- Epistaxis
- Arthralgia (caused by the spread of "blast" cells to the surface of the bone or into the joint from the marrow cavity)
References
- ↑ Clarke RT, Van den Bruel A, Bankhead C, Mitchell CD, Phillips B, Thompson MJ (October 2016). "Clinical presentation of childhood leukaemia: a systematic review and meta-analysis". Arch. Dis. Child. 101 (10): 894–901. doi:10.1136/archdischild-2016-311251. PMID 27647842.
- ↑ Vesterby A, Myhre Jensen O (September 1985). "Aseptic bone/bone marrow necrosis in leukaemia". Scand J Haematol. 35 (3): 354–7. PMID 4059858.
- ↑ Sinigaglia R, Gigante C, Bisinella G, Varotto S, Zanesco L, Turra S (2008). "Musculoskeletal manifestations in pediatric acute leukemia". J Pediatr Orthop. 28 (1): 20–8. doi:10.1097/BPO.0b13e31815ff350. PMID 18157042.
- ↑ Pui CH (January 2009). "Acute lymphoblastic leukemia: introduction". Semin. Hematol. 46 (1): 1–2. doi:10.1053/j.seminhematol.2008.09.011. PMC 2638983. PMID 19100362.
- ↑ Terwilliger T, Abdul-Hay M (June 2017). "Acute lymphoblastic leukemia: a comprehensive review and 2017 update". Blood Cancer J. 7 (6): e577. doi:10.1038/bcj.2017.53. PMC 5520400. PMID 28665419.