Acute lymphoblastic leukemia laboratory findings: Difference between revisions

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**[[Uric acid]]
**[[Uric acid]]
**[[Creatinine]]
**[[Creatinine]]
**[[Blood urea nitrogen]]
**[[Blood urea nitrogen]]<ref name="pmid25561892">{{cite journal| author=Rasool M, Farooq S, Malik A, Shaukat A, Manan A, Asif M et al.| title=Assessment of circulating biochemical markers and antioxidative status in acute lymphoblastic leukemia (ALL) and acute myeloid leukemia (AML) patients. | journal=Saudi J Biol Sci | year= 2015 | volume= 22 | issue= 1 | pages= 106-11 | pmid=25561892 | doi=10.1016/j.sjbs.2014.09.002 | pmc=4281600 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25561892  }} </ref>
**[[Potassium]]<ref name="pmid20838546">{{cite journal| author=Ali A, Aziz SA, Khan A, Gelani S| title=Persistent hypokalemia in an acute lymphoblastic leukemia patient. | journal=Indian J Med Paediatr Oncol | year= 2009 | volume= 30 | issue= 3 | pages= 103-4 | pmid=20838546 | doi=10.4103/0971-5851.64255 | pmc=2930287 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=20838546  }} </ref>
**[[Potassium]]<ref name="pmid20838546">{{cite journal| author=Ali A, Aziz SA, Khan A, Gelani S| title=Persistent hypokalemia in an acute lymphoblastic leukemia patient. | journal=Indian J Med Paediatr Oncol | year= 2009 | volume= 30 | issue= 3 | pages= 103-4 | pmid=20838546 | doi=10.4103/0971-5851.64255 | pmc=2930287 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=20838546  }} </ref>
**[[Phosphate]]
**[[Phosphate]]<ref name="pmid25561892">{{cite journal| author=Rasool M, Farooq S, Malik A, Shaukat A, Manan A, Asif M et al.| title=Assessment of circulating biochemical markers and antioxidative status in acute lymphoblastic leukemia (ALL) and acute myeloid leukemia (AML) patients. | journal=Saudi J Biol Sci | year= 2015 | volume= 22 | issue= 1 | pages= 106-11 | pmid=25561892 | doi=10.1016/j.sjbs.2014.09.002 | pmc=4281600 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25561892  }} </ref>
**[[Calcium]]
**[[Calcium]]<ref name="pmid25561892">{{cite journal| author=Rasool M, Farooq S, Malik A, Shaukat A, Manan A, Asif M et al.| title=Assessment of circulating biochemical markers and antioxidative status in acute lymphoblastic leukemia (ALL) and acute myeloid leukemia (AML) patients. | journal=Saudi J Biol Sci | year= 2015 | volume= 22 | issue= 1 | pages= 106-11 | pmid=25561892 | doi=10.1016/j.sjbs.2014.09.002 | pmc=4281600 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25561892  }} </ref>
**[[Bilirubin]]
**[[Bilirubin]]
**[[Hepatic transaminases]]
**[[Hepatic transaminases]]<ref name="pmid25561892">{{cite journal| author=Rasool M, Farooq S, Malik A, Shaukat A, Manan A, Asif M et al.| title=Assessment of circulating biochemical markers and antioxidative status in acute lymphoblastic leukemia (ALL) and acute myeloid leukemia (AML) patients. | journal=Saudi J Biol Sci | year= 2015 | volume= 22 | issue= 1 | pages= 106-11 | pmid=25561892 | doi=10.1016/j.sjbs.2014.09.002 | pmc=4281600 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25561892  }} </ref>
**[[Ferritin]]  
**[[Ferritin]]  
* A [[lumbar puncture|spinal tap]] is often required to evaluate for central nervous system involvement.
* A [[lumbar puncture|spinal tap]] is often required to evaluate for central nervous system involvement.

Revision as of 20:00, 30 January 2019

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [4] Associate Editor(s)-in-Chief: Raviteja Guddeti, M.B.B.S. [5] Carlos A Lopez, M.D. [6]

Ovierview

Laboratory findings consistent with the diagnosis of acute lymphoblastic leukemia include eosinophilia, lymphocytosis, red cell production reduced, thrombocytopenia. Chemistry panels with altered levels of uric acid, creatinine, blood urea nitrogen, potassium, phosphate, calcium, bilirubin, hepatic transaminases and ferritin.

Laboratory Findings

Laboratory findings consistent with the diagnosis of acute lymphoblastic leukemia include:[1]

Peripheral blood smear showing acute lymphoblastic leukemia [1]
Peripheral blood smear showing acute lymphoblastic leukemia [2]
Peripheral blood smear showing acute lymphoblastic leukemia [3]


References

  1. ↑ Chiaretti S, Zini G, Bassan R (2014). "Diagnosis and subclassification of acute lymphoblastic leukemia". Mediterr J Hematol Infect Dis. 6 (1): e2014073. doi:10.4084/MJHID.2014.073. PMC 4235437. PMID 25408859.
  2. ↑ Steele M, Narendran A (2012). "Mechanisms of defective erythropoiesis and anemia in pediatric acute lymphoblastic leukemia (ALL)". Ann Hematol. 91 (10): 1513–8. doi:10.1007/s00277-012-1475-5. PMID 22543829.
  3. ↑ Dubansky AS, Boyett JM, Falletta J, Mahoney DH, Land VJ, Pullen J; et al. (1989). "Isolated thrombocytopenia in children with acute lymphoblastic leukemia: a rare event in a Pediatric Oncology Group Study". Pediatrics. 84 (6): 1068–71. PMID 2587136.
  4. ↑ Rezamand A, Ghorashi Z, Ghorashi S, Nezami N (2013). "Eosinophilic presentation of acute lymphoblastic leukemia". Am J Case Rep. 14: 143–6. doi:10.12659/AJCR.883905. PMC 3715333. PMID 23869247.
  5. ↑ "National Cancer Institute".
  6. ↑ 6.0 6.1 6.2 6.3 Rasool M, Farooq S, Malik A, Shaukat A, Manan A, Asif M; et al. (2015). "Assessment of circulating biochemical markers and antioxidative status in acute lymphoblastic leukemia (ALL) and acute myeloid leukemia (AML) patients". Saudi J Biol Sci. 22 (1): 106–11. doi:10.1016/j.sjbs.2014.09.002. PMC 4281600. PMID 25561892.
  7. ↑ Ali A, Aziz SA, Khan A, Gelani S (2009). "Persistent hypokalemia in an acute lymphoblastic leukemia patient". Indian J Med Paediatr Oncol. 30 (3): 103–4. doi:10.4103/0971-5851.64255. PMC 2930287. PMID 20838546.

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