Cancer of unknown primary origin epidemiology and demographics: Difference between revisions
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Farima Kahe (talk | contribs) Created page with "__NOTOC__ {{Cancer of unknown primary origin}} {{CMG}}; {{AE}} ==Overview== ==Epidemiology and Demographics== ===Incidence=== *The incidence/prevalence of [disease name] is..." |
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==Epidemiology and Demographics== | ==Epidemiology and Demographics== | ||
===Incidence=== | ===Incidence=== | ||
* The prevalence of cancer of unknown primary origin is approximately 10 cases per 100,000 individuals worldwide.<ref name="pmid23860528">{{cite journal |vauthors=Urban D, Rao A, Bressel M, Lawrence YR, Mileshkin L |title=Cancer of unknown primary: a population-based analysis of temporal change and socioeconomic disparities |journal=Br. J. Cancer |volume=109 |issue=5 |pages=1318–24 |year=2013 |pmid=23860528 |pmc=3778275 |doi=10.1038/bjc.2013.386 |url=}}</ref><ref name="lonco">Fong T, Govindan R, Morgensztern D. Cancer of unknown primary. J Clin Oncol 2008 ASCO Ann Meet Proc. 2008;26 (15S:22159.</ref> | |||
* Cancer of unknown primary origin is common, and it accounts for 3–5% of all [[Malignant epithelial tumor|malignant epithelial tumors]].<ref name="pmid22414598">{{cite journal| author=Pavlidis N, Pentheroudakis G| title=Cancer of unknown primary site. | journal=Lancet | year= 2012 | volume= 379 | issue= 9824 | pages= 1428-35 | pmid=22414598 | doi=10.1016/S0140-6736(11)61178-1 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=22414598 }} </ref> | |||
* Cancer of unknown primary origin is the fourth most common cause of cancer-related death.<ref name="pmid23860528">{{cite journal |vauthors=Urban D, Rao A, Bressel M, Lawrence YR, Mileshkin L |title=Cancer of unknown primary: a population-based analysis of temporal change and socioeconomic disparities |journal=Br. J. Cancer |volume=109 |issue=5 |pages=1318–24 |year=2013 |pmid=23860528 |pmc=3778275 |doi=10.1038/bjc.2013.386 |url=}}</ref> | |||
===Age=== | |||
*Patients of all age groups may develop cancer of unknown primary origin. | |||
*Cancer of unknown primary origin is more commonly observed among adults and elderly patients with a mean age of 59 upon presentation.<ref name="pmid8201389">{{cite journal| author=Abbruzzese JL, Abbruzzese MC, Hess KR, Raber MN, Lenzi R, Frost P| title=Unknown primary carcinoma: natural history and prognostic factors in 657 consecutive patients. | journal=J Clin Oncol | year= 1994 | volume= 12 | issue= 6 | pages= 1272-80 | pmid=8201389 | doi=10.1200/JCO.1994.12.6.1272 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=8201389 }} </ref> | |||
===Gender=== | |||
*Cancer of unknown primary origin affects men and women equally except for [[squamous cell carcinomas]] where males are affected twice as frequently as females.<ref name="pmid8001006">{{cite journal| author=Muir C| title=Cancer of unknown primary site. | journal=Cancer | year= 1995 | volume= 75 | issue= 1 Suppl | pages= 353-6 | pmid=8001006 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=8001006 }} </ref> | |||
===Race=== | |||
*There is no racial predilection to cancer of unknown primary origin. | |||
*The incidence/prevalence of [disease name] is approximately [number range] per 100,000 individuals worldwide. | *The incidence/prevalence of [disease name] is approximately [number range] per 100,000 individuals worldwide. | ||
*In [year], the incidence/prevalence of [disease name] was estimated to be [number range] cases per 100,000 individuals worldwide. | *In [year], the incidence/prevalence of [disease name] was estimated to be [number range] cases per 100,000 individuals worldwide. | ||
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:
Overview
Epidemiology and Demographics
Incidence
* The prevalence of cancer of unknown primary origin is approximately 10 cases per 100,000 individuals worldwide.[1][2]
- Cancer of unknown primary origin is common, and it accounts for 3–5% of all malignant epithelial tumors.[3]
- Cancer of unknown primary origin is the fourth most common cause of cancer-related death.[1]
Age
- Patients of all age groups may develop cancer of unknown primary origin.
- Cancer of unknown primary origin is more commonly observed among adults and elderly patients with a mean age of 59 upon presentation.[4]
Gender
- Cancer of unknown primary origin affects men and women equally except for squamous cell carcinomas where males are affected twice as frequently as females.[5]
Race
- There is no racial predilection to cancer of unknown primary origin.
- The incidence/prevalence of [disease name] is approximately [number range] per 100,000 individuals worldwide.
- In [year], the incidence/prevalence of [disease name] was estimated to be [number range] cases per 100,000 individuals worldwide.
Prevalence
- The incidence/prevalence of [disease name] is approximately [number range] per 100,000 individuals worldwide.
- In [year], the incidence/prevalence of [disease name] was estimated to be [number range] cases per 100,000 individuals worldwide.
- The prevalence of [disease/malignancy] is estimated to be [number] cases annually.
Case-fatality rate/Mortality rate
- In [year], the incidence of [disease name] is approximately [number range] per 100,000 individuals with a case-fatality rate/mortality rate of [number range]%.
- The case-fatality rate/mortality rate of [disease name] is approximately [number range].
Age
- Patients of all age groups may develop [disease name].
- The incidence of [disease name] increases with age; the median age at diagnosis is [#] years.
- [Disease name] commonly affects individuals younger than/older than [number of years] years of age.
- [Chronic disease name] is usually first diagnosed among [age group].
- [Acute disease name] commonly affects [age group].
Race
- There is no racial predilection to [disease name].
- [Disease name] usually affects individuals of the [race 1] race. [Race 2] individuals are less likely to develop [disease name].
Gender
- [Disease name] affects men and women equally.
- [Gender 1] are more commonly affected by [disease name] than [gender 2]. The [gender 1] to [gender 2] ratio is approximately [number > 1] to 1.
Region
- The majority of [disease name] cases are reported in [geographical region].
- [Disease name] is a common/rare disease that tends to affect [patient population 1] and [patient population 2].
Developed Countries
Developing Countries
References
- ↑ 1.0 1.1 Urban D, Rao A, Bressel M, Lawrence YR, Mileshkin L (2013). "Cancer of unknown primary: a population-based analysis of temporal change and socioeconomic disparities". Br. J. Cancer. 109 (5): 1318–24. doi:10.1038/bjc.2013.386. PMC 3778275. PMID 23860528.
- ↑ Fong T, Govindan R, Morgensztern D. Cancer of unknown primary. J Clin Oncol 2008 ASCO Ann Meet Proc. 2008;26 (15S:22159.
- ↑ Pavlidis N, Pentheroudakis G (2012). "Cancer of unknown primary site". Lancet. 379 (9824): 1428–35. doi:10.1016/S0140-6736(11)61178-1. PMID 22414598.
- ↑ Abbruzzese JL, Abbruzzese MC, Hess KR, Raber MN, Lenzi R, Frost P (1994). "Unknown primary carcinoma: natural history and prognostic factors in 657 consecutive patients". J Clin Oncol. 12 (6): 1272–80. doi:10.1200/JCO.1994.12.6.1272. PMID 8201389.
- ↑ Muir C (1995). "Cancer of unknown primary site". Cancer. 75 (1 Suppl): 353–6. PMID 8001006.