Cancer of unknown primary origin pathophysiology: Difference between revisions
Jump to navigation
Jump to search
No edit summary |
No edit summary |
||
| Line 13: | Line 13: | ||
*The exact [[pathogenesis]] of cancer of unknown primary origin is not fully understood. | *The exact [[pathogenesis]] of cancer of unknown primary origin is not fully understood. | ||
*Cancer of unknown primary, like other cancers, arises from one cell that has managed to escape regulation and produces a tumor at a certain site (the site of origin) and consequently metastasizes to other parts of the body. | *Cancer of unknown primary, like other cancers, arises from one cell that has managed to escape regulation and produces a tumor at a certain site (the site of origin) and consequently metastasizes to other parts of the body. | ||
*It is thought that the site of origin of CUP remains unknown due to one of the following theories:<ref name="pmid19262901" /> | *It is thought that the site of origin of CUP remains unknown due to one or more of the following theories:<ref name="pmid19262901" /> | ||
**Remaining small and undetectable clinically | **Remaining small and undetectable clinically | ||
**Disappearing after metastasizing | **Disappearing after metastasizing | ||
| Line 19: | Line 19: | ||
* It remains unknown whether cancers of unknown primaries are [[genetically]] or [[phenotypically]] distinct from [[metastasis]] with known origins.<ref name="pmid19262901">{{cite journal |vauthors=Varadhachary GR |title=Carcinoma of unknown primary origin |journal=Gastrointest Cancer Res |volume=1 |issue=6 |pages=229–35 |year=2007 |pmid=19262901 |pmc=2631214 |doi= |url=}}</ref> | * It remains unknown whether cancers of unknown primaries are [[genetically]] or [[phenotypically]] distinct from [[metastasis]] with known origins.<ref name="pmid19262901">{{cite journal |vauthors=Varadhachary GR |title=Carcinoma of unknown primary origin |journal=Gastrointest Cancer Res |volume=1 |issue=6 |pages=229–35 |year=2007 |pmid=19262901 |pmc=2631214 |doi= |url=}}</ref> | ||
* | |||
==References== | ==References== | ||
{{Reflist|2}} | {{Reflist|2}} | ||
Revision as of 19:10, 11 February 2019
|
Cancer of unknown primary origin Microchapters |
|
Differentiating Cancer of Unknown Primary Origin from other Diseases |
|---|
|
Diagnosis |
|
Treatment |
|
Case Studies |
|
Cancer of unknown primary origin pathophysiology On the Web |
|
American Roentgen Ray Society Images of Cancer of unknown primary origin pathophysiology |
|
Cancer of unknown primary origin pathophysiology in the news |
|
Risk calculators and risk factors for Cancer of unknown primary origin pathophysiology |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: , Roukoz A. Karam, M.D.[2]
Overview
The exact pathogenesis of cancer of unknown primary origin is not fully understood.
Pathophysiology
Physiology
The normal physiology of [name of process] can be understood as follows:
Pathogenesis
- The exact pathogenesis of cancer of unknown primary origin is not fully understood.
- Cancer of unknown primary, like other cancers, arises from one cell that has managed to escape regulation and produces a tumor at a certain site (the site of origin) and consequently metastasizes to other parts of the body.
- It is thought that the site of origin of CUP remains unknown due to one or more of the following theories:[1]
- Remaining small and undetectable clinically
- Disappearing after metastasizing
- Elimination by body's defense
- It remains unknown whether cancers of unknown primaries are genetically or phenotypically distinct from metastasis with known origins.[1]