Chronic lymphocytic leukemia diagnostic study of choice

Chronic lymphocytic leukemia Microchapters
Home
Patient Information
Overview
Historical Perspective
Classification
Pathophysiology
Causes
Differentiating Chronic lymphocytic leukemia from other Diseases
Epidemiology and Demographics
Risk Factors
Screening
Natural History, Complications and Prognosis
Diagnosis
Diagnostic Study of Choice
Staging
History and Symptoms
Physical Examination
Laboratory Findings
Electrocardiogram
Chest X Ray
CT
MRI
Echocardiography or Ultrasound
Other Imaging Findings
Other Diagnostic Studies
Treatment
Medical Therapy
Surgery
Primary Prevention
Secondary Prevention
Cost-Effectiveness of Therapy
Future or Investigational Therapies
Case Studies
Case #1
Chronic lymphocytic leukemia diagnostic study of choice On the Web
Most recent articles
cited articles
Review articles
CME Programs
Powerpoint slides
Images
American Roentgen Ray Society Images of Chronic lymphocytic leukemia diagnostic study of choice All Images X-rays Echo & Ultrasound CT Images MRI
Ongoing Trials at Clinical Trials.gov
US National Guidelines Clearinghouse
NICE Guidance
FDA on Chronic lymphocytic leukemia diagnostic study of choice
CDC on Chronic lymphocytic leukemia diagnostic study of choice
Chronic lymphocytic leukemia diagnostic study of choice in the news
Blogs on Chronic lymphocytic leukemia diagnostic study of choice
Directions to Hospitals Treating Chronic lymphocytic leukemia
Risk calculators and risk factors for Chronic lymphocytic leukemia diagnostic study of choice

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Shyam Patel [2]

Overview

The diagnostic study of choice in chronic lymphocytic leukemia is peripheral blood flow cytometry.

Diagnostic study of choice

The diagnostic study of choice in chronic lymphocytic leukemia is peripheral blood flow cytometry. If peripheral blood flow cytometry shows greater than 5000 clonal B cell per microliter, the diagnosis is confirmed. Ancillary tests include bone marrow biopsy and peripheral blood cytogenetics or FISH studies.

Chronic lymphocytic leukemia is diagnosed according to the International Workshop on Chronic Lymphocytic Leukemia (iwCLL) guidelines:

• Complete blood count (CBC) with differential: Absolute lymphocytosis ≥5000 B-lymphocytes/µL X ≥ 3 months
• Flow cytometry: