Ovarian cancer differential diagnosis: Difference between revisions
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* History/imaging | * History/<br>imaging | ||
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* It is associated with hyperestrogenism and endometrial hyperplasia | * It is associated with hyperestrogenism and endometrial hyperplasia | ||
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* theca interna cell Hyperplasia | * theca interna cell Hyperplasia | ||
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* History/imaging | * History/<br>imaging | ||
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* It is associated with hydatidiform moles, choriocarcinoma, diabetes mellitus and clomiphene intake (ovulation induction) | * It is associated with hydatidiform moles, choriocarcinoma, diabetes mellitus and clomiphene intake (ovulation induction) | ||
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* Mucin-secreting signet cell | * Mucin-secreting signet cell | ||
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* Imaging/biopsy | * Imaging/<br>biopsy | ||
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* The most common primary tumor is in colon, stomach, breast, lung, and contralateral ovary | * The most common primary tumor is in colon, stomach, breast, lung, and contralateral ovary | ||
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* In abscess aspiration we may see anaerobic organisms | * In abscess aspiration we may see anaerobic organisms | ||
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* History/imaging | * History/<br>imaging | ||
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*The most common risk factors are previous PID, diabetes mellitus, intrauterine device and history of uterine surgery | *The most common risk factors are previous PID, diabetes mellitus, intrauterine device and history of uterine surgery | ||
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* History/imaging | * History/<br>imaging | ||
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* Any women in reproductive age presenting with abdominal pain or [[amenorrhea]] should be screened for ectopic pregnancy | * Any women in reproductive age presenting with abdominal pain or [[amenorrhea]] should be screened for ectopic pregnancy | ||
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* History/physical exam | * History/<br>physical exam | ||
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* It may cause infertility | * It may cause infertility | ||
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* [[History and Physical examination|History]]/[[laboratory]] findings | * [[History and Physical examination|History]]/<br>[[laboratory]] findings | ||
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* We do not perform [[CT scan]] and [[MRI]] in [[pregnancy]] but We may unintentionally image the [[pregnancy]] with [[CT scan]] and [[MRI]]. | * We do not perform [[CT scan]] and [[MRI]] in [[pregnancy]] but We may unintentionally image the [[pregnancy]] with [[CT scan]] and [[MRI]]. | ||
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* [[Imaging]]/[[History and Physical examination|history]] | * [[Imaging]]/<br>[[History and Physical examination|history]] | ||
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* The most common [[complication]] of [[acute appendicitis]] | * The most common [[complication]] of [[acute appendicitis]] | ||
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* [[Imaging]]/[[History and Physical examination|history]] | * [[Imaging]]/<br>[[History and Physical examination|history]] | ||
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* [[Diverticular abscess]] happens in almost 30-40% of patients with [[diverticulitis]] | * [[Diverticular abscess]] happens in almost 30-40% of patients with [[diverticulitis]] |
Revision as of 14:30, 11 February 2019
Ovarian cancer Microchapters |
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Ovarian cancer differential diagnosis On the Web |
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Risk calculators and risk factors for Ovarian cancer differential diagnosis |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Fahimeh Shojaei, M.D.
Overview
Differentiating [Disease name] from other Diseases
Diseases | Clinical manifestations | Para-clinical findings | Gold standard | Additional findings | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Age of onset | Symptoms | Physical examination | |||||||||||
Lab Findings | Imaging | Immunohistopathology | |||||||||||
pelvic/abdominal pain or pressure | vaginal bleeding/discharge | GI dysturbance | Fever | Tenderness | CT scan/US | MRI | |||||||
Gynecologic | |||||||||||||
Ovarian | Follicular cysts |
|
+/– | – | – | – | +/– |
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Theca lutein cysts |
|
+/– | – | – | – | +/– |
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Serous cystadenoma/carcinoma |
|
– |
|
| |||||||||
Mucinous cystadenoma/carcinoma |
|
– |
| ||||||||||
Endometrioma |
|
+ | + | +/– | – | + |
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|
| |
Teratoma |
|
+/– | – | – | – | +/– |
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Dysgerminoma |
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+ | +/– | – | – | +/– |
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Yolk sac tumor |
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+ | – | – | – | + |
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| |
Fibroma |
|
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– | – | – | +/– |
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Thecoma |
|
+/– |
|
– | – | – |
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Granulosa cell tumor |
|
+ |
|
+/– | – | – |
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Sertoli-leydig cell tumor |
|
+/– | – | – | – | – |
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Brenner tumor |
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+/– | – | – | – | – | – |
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Krukenberg tumor |
|
+/– | – | +/–
Based on underlying malignancy |
– | – |
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Tubal | tubo-ovarian abscess |
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+ | + | – | + | + |
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Ectopic pregnancy |
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+ | + | +/– | – | + |
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Hydrosalpinx |
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+ | – | – | – | +/– | – |
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Salpingitis |
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+ | + | – | + | + |
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Fallopian tube carcinoma |
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+ | + | + | – | +/– |
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Uterine | Leiomyoma |
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+ | + | – | – | +/– |
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Choriocarcinoma |
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+ | + | +/– | – | + |
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Leiomyosarcoma |
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+ | + | – | – | +/– |
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Pregnancy |
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+/− | +/− | +/− | – | – |
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Non-gynecologic | |||||||||||||
GIT | Appendiceal abscess |
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+ | – | + | +/– | + |
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| ||
Appendiceal neoplasm[1] |
|
+ | – | + | – | +/– |
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| ||
Diverticular abscess |
|
+ | – | + | +/– | + |
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| |||
Colorectal cancer |
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+ | – | + | – | +/– |
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| ||
Renal | Pelvic kidney |
|
−/+
In case of sever hydronephrosis or renal stone we may have pelvic pain |
– | − | − | − | − |
|
|
|
| |
Bladder cancer |
|
+ | – | – | – | – |
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| ||
Others | Retroperitoneal sarcoma[2] |
|
+ | – | + | − | − |
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|
|
|
check sites of cancer that may metastasize to the ovaries (eg, stomach, colorectal, breast)
check rectum, liver, spleen, lungs, inguinal or supraclavicular lymph nodes for ovary metastase
- Bladder tumour–associated antigen (BTA)
- Nuclear matrix proteins (NMP)
- Mucin and carcinoembryonic antigen (CEA)
References
- ↑ Chapter 5: Tumours of the Appendix - IARC. https://www.iarc.fr/en/publications/pdfs-online/pat-gen/bb2/bb2-chap5.pdf Accessed on January 15, 2019
- ↑ Storm FK, Mahvi DM (July 1991). "Diagnosis and management of retroperitoneal soft-tissue sarcoma". Ann. Surg. 214 (1): 2–10. PMC 1358407. PMID 2064467.