Gonadoblastoma epidemiology and demographics: Difference between revisions
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* | *Gonadoblastoma affects individuals of any age but tends to present at a greater extent prior to 15 years of age.<ref name="pmid4193741">{{cite journal| author=Scully RE| title=Gonadoblastoma. A review of 74 cases. | journal=Cancer | year= 1970 | volume= 25 | issue= 6 | pages= 1340-56 | pmid=4193741 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=4193741 }}</ref> | ||
Gonadoblastoma affects individuals of any age but tends to present at a greater extent prior to 15 years of age | |||
===Race=== | ===Race=== | ||
*There is no racial predilection to gonadoblastoma. | *There is no racial predilection to gonadoblastoma. | ||
Revision as of 16:01, 13 February 2019
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sahar Memar Montazerin, M.D.[2]
Overview
The prevalence of gonadoblastoma varied depend on the chromosomal content, presence or absence of mosaicism, gonadal histology and age of the patient between 15% to 30%. The incidence of gonadoblastoma varied according to the presence or absence of Y chromosomal content and age of the individual. Patients with Turner syndrome who have Y chromosomal content either completely or partially can develop gonadoblastoma with an incidence as high as 43%. Phenotypical female with XY gonadal abnormalities have been observed to develop gonadoblastoma by 40%.
Epidemiology and Demographics
Incidence
- The incidence of gonadoblastoma varied according to the presence or absence of Y chromosomal content and age of the individual.[1][2]
- Phenotypical female with XY gonadal abnormalities have been observed to develop gonadoblastoma by 40%.
- Patients with Turner syndrome who have Y chromosomal content either completely or partially can develop gonadoblastoma with an incidence as high as 43%.
Prevalence
- The prevalence of gonadoblastoma varied depend on the chromosomal content, presence or absence of mosaicism, gonadal histology and age of the patient between 15% to 30%.[3]
Age
- Gonadoblastoma affects individuals of any age but tends to present at a greater extent prior to 15 years of age.[4]
Race
- There is no racial predilection to gonadoblastoma.
Gender
The majority of affected patients (80%) are phenotypically women.[4]
References
- ↑ Brant WO, Rajimwale A, Lovell MA, Travers SH, Furness PD, Sorensen M, Oottamasathien S, Koyle MA (May 2006). "Gonadoblastoma and Turner syndrome". J. Urol. 175 (5): 1858–60. doi:10.1016/S0022-5347(05)0032-8. PMID 16600779.
- ↑ Sperling, M (2014). Pediatric endocrinology. Philadelphia, PA: Elsevier/Saunders. ISBN 978-1-4557-4858-7.
- ↑ "Yen & Jaffe's Reproductive Endocrinology | ScienceDirect".
- ↑ 4.0 4.1 Scully RE (1970). "Gonadoblastoma. A review of 74 cases". Cancer. 25 (6): 1340–56. PMID 4193741.