Gonadoblastoma history and symptoms: Difference between revisions
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==Overview== | ==Overview== | ||
Patients with gonadoblastoma present either during infancy with ambiguous genitalia or later with sexual developmental complaints. The hallmark of gonadoblastoma is gonadal developmental disorders. The majority of affected individuals are phenotypically women and may be discovered during a workup for [[virilization]] and/or [[primary amenorrhea]]. Others are phenotypically men with sex organs developmental problems such as [[cryptorchidism]] and [[hypospadias]].Although very rarely, gonadoblastoma has been found in anatomically normal male individuals. In this individuals, it may present with a sense of discomfort or pain in testicles. | |||
The hallmark of | |||
===History=== | ===History=== | ||
Patients with gonadoblastoma may have a positive history of:<ref name="978-0-323-40067-1">{{cite book | last = Saia | first = Philip | title = Clinical gynecologic oncology | publisher = Elsevier | location = Philadelphia, PA | year = 2018 | isbn = 978-0-323-40067-1 }}</ref><ref name="pmid2231948">{{cite journal |vauthors=Chapman WH, Plymyer MR, Dresner ML |title=Gonadoblastoma in an anatomically normal man: a case report and literature review |journal=J. Urol. |volume=144 |issue=6 |pages=1472–4 |date=December 1990 |pmid=2231948 |doi= |url=}}</ref> | Patients with gonadoblastoma may have a positive history of:<ref name="978-0-323-40067-1">{{cite book | last = Saia | first = Philip | title = Clinical gynecologic oncology | publisher = Elsevier | location = Philadelphia, PA | year = 2018 | isbn = 978-0-323-40067-1 }}</ref><ref name="pmid2231948">{{cite journal |vauthors=Chapman WH, Plymyer MR, Dresner ML |title=Gonadoblastoma in an anatomically normal man: a case report and literature review |journal=J. Urol. |volume=144 |issue=6 |pages=1472–4 |date=December 1990 |pmid=2231948 |doi= |url=}}</ref> | ||
Revision as of 21:48, 13 February 2019
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:
Overview
Patients with gonadoblastoma present either during infancy with ambiguous genitalia or later with sexual developmental complaints. The hallmark of gonadoblastoma is gonadal developmental disorders. The majority of affected individuals are phenotypically women and may be discovered during a workup for virilization and/or primary amenorrhea. Others are phenotypically men with sex organs developmental problems such as cryptorchidism and hypospadias.Although very rarely, gonadoblastoma has been found in anatomically normal male individuals. In this individuals, it may present with a sense of discomfort or pain in testicles.
History
Patients with gonadoblastoma may have a positive history of:[1][2]
- Ambiguous genitalia
- sexual development disorders
- Hypospadias or undescended testis
Common Symptoms
Common symptoms of gonadoblastoma include:
- Primary amenorrhea
- virilization
Less Common Symptoms
Less common symptoms of gonadoblastoma include:
- growing mass in testicles
- Chronic pain in testis
- Low abdominal mass in phenotypically normal women