Gonadoblastoma risk factors: Difference between revisions
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==Overview== | ==Overview== | ||
The most potent [[risk factor]] in the development of gonadoblastoma is [[gonadal dysgenesis]]. The risk also increases with age. | The most potent [[risk factor]] in the development of gonadoblastoma is [[gonadal dysgenesis]]. The [[risk]] also increases with [[age]]. | ||
==Risk Factors== | ==Risk Factors== | ||
*The most potent [[risk factor]] in the development of gonadoblastoma is [[gonadal dysgenesis]].<ref name="EsinBaser2011">{{cite journal|last1=Esin|first1=Sertac|last2=Baser|first2=Eralp|last3=Kucukozkan|first3=Tuncay|last4=Magden|first4=Hasim Ata|title=Ovarian gonadoblastoma with dysgerminoma in a 15-year-old girl with 46, XX karyotype: case report and review of the literature|journal=Archives of Gynecology and Obstetrics|volume=285|issue=2|year=2011|pages=447–451|issn=0932-0067|doi=10.1007/s00404-011-2073-9}}</ref><ref name="978-1-4557-4858-7">{{cite book | last = Sperling | first = M | title = Pediatric endocrinology | publisher = Elsevier/Saunders | location = Philadelphia, PA | year = 2014 | isbn = 978-1-4557-4858-7 }}</ref> | *The most potent [[risk factor]] in the development of gonadoblastoma is [[gonadal dysgenesis]].<ref name="EsinBaser2011">{{cite journal|last1=Esin|first1=Sertac|last2=Baser|first2=Eralp|last3=Kucukozkan|first3=Tuncay|last4=Magden|first4=Hasim Ata|title=Ovarian gonadoblastoma with dysgerminoma in a 15-year-old girl with 46, XX karyotype: case report and review of the literature|journal=Archives of Gynecology and Obstetrics|volume=285|issue=2|year=2011|pages=447–451|issn=0932-0067|doi=10.1007/s00404-011-2073-9}}</ref><ref name="978-1-4557-4858-7">{{cite book | last = Sperling | first = M | title = Pediatric endocrinology | publisher = Elsevier/Saunders | location = Philadelphia, PA | year = 2014 | isbn = 978-1-4557-4858-7 }}</ref> | ||
*The risk of gonadoblastoma development increases with age. In individuals with XY [[gonadal]] abnormalities, it reaches | *The risk of gonadoblastoma development increases with age. In individuals with XY [[gonadal]] [[abnormalities]], it reaches up to 30% by the [[age]] of thirty years. | ||
*Other [[risk factors]] include patients with [[Turner syndrome]] and having [[Y chromosome]] contents. | *Other [[risk factors]] include patients with [[Turner syndrome]] and having [[Y chromosome]] contents. | ||
==References== | ==References== |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sahar Memar Montazerin, M.D.[2]
Overview
The most potent risk factor in the development of gonadoblastoma is gonadal dysgenesis. The risk also increases with age.
Risk Factors
- The most potent risk factor in the development of gonadoblastoma is gonadal dysgenesis.[1][2]
- The risk of gonadoblastoma development increases with age. In individuals with XY gonadal abnormalities, it reaches up to 30% by the age of thirty years.
- Other risk factors include patients with Turner syndrome and having Y chromosome contents.
References
- ↑ Esin, Sertac; Baser, Eralp; Kucukozkan, Tuncay; Magden, Hasim Ata (2011). "Ovarian gonadoblastoma with dysgerminoma in a 15-year-old girl with 46, XX karyotype: case report and review of the literature". Archives of Gynecology and Obstetrics. 285 (2): 447–451. doi:10.1007/s00404-011-2073-9. ISSN 0932-0067.
- ↑ Sperling, M (2014). Pediatric endocrinology. Philadelphia, PA: Elsevier/Saunders. ISBN 978-1-4557-4858-7.