Epithelial ovarian cancer: Difference between revisions

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Revision as of 14:58, 26 February 2019


Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Hannan Javed, M.D.[2]

Possible genetic alteration in epithelial ovarian cancers
Protein Normal function Result of mutation
EGFR(HER-1)
HER-2
Src
CSF-1/fms
ILGF/ILGFR
k-ras
b-raf
TGF-β
myc
Cyclin D/Cdk4/6
Cyclin E/Cdk2
Cyclin B/Cdk1
p16
p27 (kip-1)
p21 (WAF-1)
NFκB
NOEY(ARHI)
PIP3/Akt
PTEN
p53
BRCA1
BRCA2
MLH1/MSH2
Fas ligand
HLA-G
hTERT
VEGF/VEGFR
IL-8
EphA2
MMPs
αvβ3
FAK
E-cadherin

References