Desmoid tumor natural history, complications, and prognosis: Difference between revisions
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{{Desmoid tumor}} | {{Desmoid tumor}} | ||
{{CMG}} {{AE}}{{Faizan}} | {{CMG}} {{AE}}{{S.M.}}{{Faizan}} | ||
==Overview== | ==Overview== | ||
If left untreated, desmoid tumor produces few symptoms early in the course. Common complications of desmoid tumor include progression to agressive fibromatosis, involvement of intra abdominal viscera, and metastasis. The prognosis varies with the associated disease of desmoid tumor. Desmoid tumor associated with FAP has the least favorable prognosis. | If left untreated, desmoid tumor produces few symptoms early in the course. Common complications of desmoid tumor include progression to agressive fibromatosis, involvement of intra abdominal viscera, and metastasis. The prognosis varies with the associated disease of desmoid tumor. Desmoid tumor associated with FAP has the least favorable prognosis. |
Revision as of 17:13, 27 February 2019
Desmoid tumor Microchapters |
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Treatment |
Case Studies |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Sara Mohsin, M.D.[2]Faizan Sheraz, M.D. [3]
Overview
If left untreated, desmoid tumor produces few symptoms early in the course. Common complications of desmoid tumor include progression to agressive fibromatosis, involvement of intra abdominal viscera, and metastasis. The prognosis varies with the associated disease of desmoid tumor. Desmoid tumor associated with FAP has the least favorable prognosis.
Natural history
- If left untreated, desmoid tumor produces few symptoms early in the course.
Complications
Common complications of desmoid tumor include:
- Progression to aggressive fibromatosis
- Involvement of intra abdominal organs
- Metastasis
Prognosis
- Desmoid tumors have become an important cause of morbidity and mortality due to increasing use of prophylactic colectomy in FAP patients
- Desmoids when become massive and inoperable, can cause death in approximately 11% of FAP patients post-colectomy surgery
- Due to gradual progression to desmoids, 60% of FAP patients remain alive for 10 years after the diagnosis
- Pregnancy-associated desmoid fibromatosis is associated with overall good outcomes