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| __NOTOC__ | | __NOTOC__ |
| | | {{familytree/start |summary=PE diagnosis Algorithm.}} |
| {{familytree/start |summary=Sample 1}} | | {{familytree | | | | | | | | | | A02 | | | | | |A02=Malignant germ cell tumor}} |
| {{familytree | | | | | | | | A01 |A01=Germ cell}} | | {{familytree | | | |,|-|-|-|-|-|-|^|-|-|-|-|-|-|-|.| | | | | | }} |
| {{familytree | | | | |,|-|-|-|^|-|-|-|-|.| | | }} | | {{familytree | | | C01 | | | | | | | | | | | | | C02 | | |C01=Prior surgery|C02=Initial surgery}} |
| {{familytree | | | B01 | | | | | | | | B02 | | |B01=Pathogenesis|B02=Malignant transformation}} | | {{familytree | |,|-|^|-|.| | | | | | | | | | |,|-|^|-|.| | }} |
| {{familytree | | | |!| | | | | | | | | |!| }} | | {{familytree | D01 | | D02 | | | | | | | | | D03 | | D04 |D01=Complete staging|D02=Incomplete staging|D03=Fertility sparing prefered|D04=Fertility sparing not prefered}} |
| {{familytree | | | C01 | | | | | | | | |!| |C01=Mature teratoma}} | | {{familytree | |!| | | |!| | | | | | | | | | |!| | | |!| | }} |
| {{familytree | | | | | | | | | | | | | |!}} | | {{familytree | E01 | | E02 | | | | | | | | | E03 | | E04 |E01=Treatment based<br>on<br>the staging|E02=Imaging:<br>Chest/<br>abdomen/<br>pelvis CT with contrast|E03=Fertility sparing surgery<br>and<br>complete staging|E04=Surgery to stage}} |
| {{familytree | | | | | | | | | |,|-|-|-|+|-|-|-|.| }} | | {{familytree | | | | | |!| | | | | | | | | | |!| | | |!| | | | }} |
| {{familytree | | | | | | | | | E01 | | E02 | | E03 |E01=Tumors esxpressing transcription factors of pluripotency|E02=Tumors with primitive embryonic ectoderm, mesoderm, and/or endoderm differentiation|E03=Tumors with extraembroyonic differentiation}} | | {{familytree | | | | | |!| | | | | | | | | | |`| F02 |'| | | |F02=Treatment based on the staging}} |
| {{familytree | | | | | | | | | |!| | | |!| | | |!| | }} | | {{familytree | | | |,|-|^|-|-|-|-|-|-|-|-|-|.| | | | | | | }} |
| {{familytree | | | | | | | | | F01 | | F02 | | F03 | |F01=Dysgerminoma/Embryonal carcinoma|F02=Immature teratoma|F03=Yolk sac tumor/Choriocarcinoma}} | | {{familytree | | | G01 | | | | | | | | | | G02 | | | | | | | | | | | | |G01=Yolk sac tumor<br>grade2-3 immature teratoma<br>non-gestational choriocarcinoma<br>or mixed histology|G02=Dysgerminoma<br>or<br>grade 1 immature teratoma}} |
| | {{familytree | | | |!| | | | | | | | | | | |!| | | | | | | | | | | | | | | }} |
| | {{familytree | | | |!| | | | | | | |'|-|-|-|+|-|-|-|-|.|}} |
| | {{familytree | | | |!| I02 | | I03 | | | I04 | | | |I02=I02|I03=I03|I04=I04}} |
| | {{familytree | | | I01 | | | | | | | | | | | | | | | | | |I01=I01|I02=I02}} |
| | {{familytree | |,|-|^|-|.| | | | | | | | | | | | | | | | | | |}} |
| | {{familytree | J01 | | J02 | | | | | | | | | | | | | | | | | | |J01=J01|J02=J02}} |
| | {{familytree | |!| | | | | | | | | | | | | | | | | | | | | |}} |
| | {{familytree | K01 | | | | | | | | | | | | | | | | | | | |K01=K01}} |
| | {{familytree | | | | | | | | | | | | | | | | | | | | | | | |}} |
| | {{familytree | | | | | | | | | | | | | | | | | | | | | | | |}} |
| {{familytree/end}} | | {{familytree/end}} |
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| {| class="wikitable"
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| |+
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| ! colspan="3" style="background:#4479BA; color: #FFFFFF;" align="center" + |Primary tumor
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| |-
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| | align="center" style="background:#f0f0f0;" |'''Tumor size'''
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| | align="center" style="background:#f0f0f0;" |'''FIGO stage'''
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| | align="center" style="background:#f0f0f0;" |'''Finding'''
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| |-
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| | T1
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| | I||Growth limited to one or both [[ovaries]],
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| |-
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| | T1a
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| | Ia||Growth limited to one [[ovary]]; no [[ascites]] present containing [[malignant]] cells. No [[tumor]] on the external [[Surface anatomy|surface]]; [[capsule]] intact
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| |-
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| | T1b
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| | Ib||Growth limited to one or both [[ovaries]]; no [[ascites]] present containing [[malignant]] cells. No [[tumor]] on the external [[Surface anatomy|surfaces]]; [[capsules]] intact
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| |-
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| | T1c
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| | Ic||[[Tumor]] either stage Ia or Ib, but with the [[tumor]] on [[Surface anatomy|surface]] of one or both [[ovaries]], or with [[capsule]] [[Rupture|ruptured]], or with [[ascites]] present containing [[malignant]] cells, or with positive [[peritoneal]] washings
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| |-
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| | T2
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| | II||Growth involving one or both [[ovaries]] with [[pelvic]] extension
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| |-
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| | T2a
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| | IIa||Extension and/or [[metastases]] to the [[uterus]] and/or tubes
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| |-
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| | T2b
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| | IIb||Extension to other [[pelvic]] tissues
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| |-
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| | T2c
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| | IIc||[[Tumor]] either stage IIa or IIb, but with the [[tumor]] on [[Surface anatomy|surface]] of one or both [[ovaries]], or with [[Capsule|capsule(s)]] ruptured, or with [[ascites]] present containing [[malignant]] cells, or with positive [[peritoneal]] washings
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| |-
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| | T3
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| | III||[[Tumor]] involving one or both [[ovaries]] with [[histologically]] confirmed [[peritoneal]] implants outside the [[pelvis]] and/or positive regional [[lymph nodes]]. [[Superficial]] [[liver]] [[metastases]] equal stage III. The [[tumor]] is limited to the [[true pelvis]], but with [[histologically]] proven [[malignant]] extension to [[small bowel]] or [[omentum]]
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| |-
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| | T3a
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| | IIIa2||[[Tumor]] grossly limited to the [[true pelvis]] with [[histologically]] confirmed microscopic seeding of [[abdominal]] [[peritoneal]] surfaces, or [[histologic]] proven extension to [[small bowel]] or [[mesentery]] with or without positive retroperitoneal lymph nodes
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| |-
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| | T3b
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| | IIIb||[[Tumor]] of one or both [[ovaries]] with [[histologically]] confirmed implants, [[peritoneal]] [[metastasis]] of [[abdominal]] [[peritoneal]] surfaces, none exceeding 2 cm in diameter with or without metastasis to the retroperitoneal lymph nodes
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| |-
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| | T3c
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| | IIIc||[[Peritoneal]] [[metastasis]] beyond the pelvis >2 cm in diameter with or without metastasis to the retroperitoneal lymph nodes (includes extension of tumor to capsule of liver and spleen without parenchymal involvement of either organ)
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| |-
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| | AnyT
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| | IV||Growth involving one or both [[ovaries]] with distant [[Metastasis|metastases]]. If [[pleural effusion]] is present, there must be positive [[cytology]] to allow a case to stage IV. Parenchymal liver metastasis equals stage IV.
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| |-
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| |+
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| ! colspan="3" style="background:#4479BA; color: #FFFFFF;" align="center" + |Regional lymph node involvement
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| |-
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| | align="center" style="background:#f0f0f0;" |'''Node involvement'''
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| | align="center" style="background:#f0f0f0;" |'''FIGO stage'''
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| | align="center" style="background:#f0f0f0;" |'''Finding'''
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| |-
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| | N0
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| | ||No lymph node involvement
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| |-
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| | N0(i+)
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| | ||Tumor cells are present in regional lymph node(s), no greater than 0.2 mm
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| |-
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| | N1
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| | IIIA1||Histologically confirmed retroperitoneal lymph nodes
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| |-
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| | N1a
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| | IIIA1i||Metastasis <and= 10 mm in greatest dimension
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| |-
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| | N1b
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| | IIIA1ii||Metastasis more than 10 mm in greatest dimension
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| |-
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| |+
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| ! colspan="3" style="background:#4479BA; color: #FFFFFF;" align="center" + |Distant metastasis
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| |-
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| | align="center" style="background:#f0f0f0;" |'''Presence of metastasis'''
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| | align="center" style="background:#f0f0f0;" |'''FIGO stage'''
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| | align="center" style="background:#f0f0f0;" |'''Finding'''
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| |-
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| | M0
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| | ||No distant metastasis
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| |-
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| | M1
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| | IV||Distant metastasis, including positive cytology of pleural effusion; liver or splenic parenchymal metastasis; metastasis to extra-abdominal organs (including inguinal lymph nodes and lymph nodes outside the abdominal cavity); and transmural involvement of intestine
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| |-
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| | M1a
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| | IVa||Pleural effusion with positive cytology
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| |-
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| | M1b
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| | IVb||Liver or splenic parenchymal metastases; metastases to extra-abdominal organs (including inguinal lymph nodes and lymph nodes outside the abdominal cavity); transmural involvement of intestine
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| |-
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| |}
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