Neurofibroma classification

Neurofibroma Microchapters
Home
Patient Information
Overview
Historical Perspective
Classification
Pathophysiology
Causes
Differentiating Neurofibroma from other Diseases
Epidemiology and Demographics
Risk Factors
Screening
Natural History, Complications and Prognosis
Diagnosis
Diagnostic Study of Choice
Staging
History and Symptoms
Physical Examination
Laboratory Findings
X Ray
CT
MRI
Ultrasound
Other Imaging Findings
Other Diagnostic Studies
Treatment
Medical Therapy
Surgery
Primary Prevention
Secondary Prevention
Cost-Effectiveness of Therapy
Future or Investigational Therapies
Case Studies
Case #1
Neurofibroma classification On the Web
Most recent articles
Most cited articles
Review articles
CME Programs
Powerpoint slides
Images
American Roentgen Ray Society Images of Neurofibroma classification All Images X-rays Echo & Ultrasound CT Images MRI
Ongoing Trials at Clinical Trials.gov
US National Guidelines Clearinghouse
NICE Guidance
FDA on Neurofibroma classification
CDC on Neurofibroma classification
Neurofibroma classification in the news
Blogs on Neurofibroma classification
Directions to Hospitals Treating Neurofibroma
Risk calculators and risk factors for Neurofibroma classification

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sara Mohsin, M.D.[2] Shanshan Cen, M.D. [3]

Overview

Neurofibroma may be classified into 5 subtypes: cutaneous/dermal/localized, subcutaneous, diffuse, intramuscular, and plexiform neurofibroma. Plexiform neurofibromas may be further sub-classified into diffuse and nodular plexiform.

Classification

Neurofibroma may be classified into following 5 subtypes:

Types of neurofibromas	Characteristics/Description
Cutaneous/Dermal/Localized (90%)	Most common These are skin tumors
Subcutaneous	Common Present underneath the skin Can be single tumors or chains They are often a form of plexiform neurofibromas
Diffuse	Uncommon Squishy Run through the full skin thickness Edges are difficult to define
Intramuscular	Common Usually isolated tumors in the muscle Sometimes can occur in chains and are plexiform neurofibromas
Plexiform	Usually present on large nerves Have more connective tissue that separates the nerve fibers Generally believed to be present at birth

Plexiform neurofibromas can be further subclassified into following:

Types of neurofibromas	Characteristics/Description
Diffuse Plexiform	It extends through the skin into fascia and muscle Has “little fingers” that invade muscle or other tissue May have a large café au lait spot “above” it
Nodular Plexiform	Usually involves nerves coming off the spinal cord or off of larger nerves Usually enlarges or thickens the nerve Looks like little clusters of tumors along the nerve

References

Template:WikiDoc Sources