Ovarian germ cell tumor medical therapy: Difference between revisions
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Raditherapy is not anymore the first opttion of tratment for [[dysgerminoma]] considering its association with ovarian failure development. | Raditherapy is not anymore the first opttion of tratment for [[dysgerminoma]] considering its association with ovarian failure development. | ||
==Radiotherapy== | ==Radiotherapy== | ||
* Not all the [[ovarian]] [[germ cell]] [[tumors]] are [[radiosensitive]]. <ref name=" | * Not all the [[ovarian]] [[germ cell]] [[tumors]] are [[radiosensitive]].<ref name="pmid12733128">{{cite journal |vauthors=Chen VW, Ruiz B, Killeen JL, Coté TR, Wu XC, Correa CN |title=Pathology and classification of ovarian tumors |journal=Cancer |volume=97 |issue=10 Suppl |pages=2631–42 |date=May 2003 |pmid=12733128 |doi=10.1002/cncr.11345 |url=}}</ref> | ||
* [[Dysgerminoma]] is a [[radiosensitive]] [[tumor]]. | * [[Dysgerminoma]] is a [[radiosensitive]] [[tumor]]. | ||
* [[Radiotherapy]] is not the first option for treating [[dysgerminoma]] and it reserved for patients for whom [[chemotherapy]] is contraindicated for whatever reason. | * [[Radiotherapy]] is not the first option for treating [[dysgerminoma]] and it reserved for patients for whom [[chemotherapy]] is contraindicated for whatever reason. | ||
Revision as of 15:31, 26 March 2019
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Sahar Memar Montazerin, M.D.[2]
Overview
Among ovarian germ cell tumors, only dysgerminoma is radiosensitive. Raditherapy is not anymore the first opttion of tratment for dysgerminoma considering its association with ovarian failure development.
Radiotherapy
- Not all the ovarian germ cell tumors are radiosensitive.[1]
- Dysgerminoma is a radiosensitive tumor.
- Radiotherapy is not the first option for treating dysgerminoma and it reserved for patients for whom chemotherapy is contraindicated for whatever reason.
- Whole abdomina radiotherapy is used for the treatment of dysgerminoma, however, it may be associated with ovarian failure.[2]
References
- ↑ Chen VW, Ruiz B, Killeen JL, Coté TR, Wu XC, Correa CN (May 2003). "Pathology and classification of ovarian tumors". Cancer. 97 (10 Suppl): 2631–42. doi:10.1002/cncr.11345. PMID 12733128.
- ↑ Mitchell, Michele Follen; Gershenson, David M.; Soeters, Robbert-Paul; Eifel, Patricia J.; Delclos, Luis; Wharton, J. Taylor (1991). "Long-term effects of radiation therapy on patients with ovarian dysgerminoma". Cancer. 67 (4): 1084–1090. doi:10.1002/1097-0142(19910215)67:4<1084::AID-CNCR2820670436>3.0.CO;2-E. ISSN 0008-543X.