Neurofibroma MRI: Difference between revisions

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Revision as of 17:22, 26 March 2019

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sara Mohsin, M.D.[2] Shanshan Cen, M.D. [3]

MRI may be helpful in the diagnosis of neurofibroma.


MRI sequence	Characteristics
T1	Hypointense Homogeneous low signal intensity Center demonstrating a higher signal intensity than the periphery (reverse of target sign on T2)
T2	Hyperintense Homogeneous high signal intensity (higher than fat) Target sign (low signal intensity centrally with a ring of high signal intensity peripherally) in case of plexiform neurofibromas Plexiform neurofibromas may appear as a larger and more infiltrating mass with lobulated borders with inhomogeneous enhancement Myxoid stroma enhancement helps differentiating the high signal intensity at T2-weighted imaging from cystic change or necrosis
T1 with gadolinium contrast	Heterogenous enhancement

↑ Neurofibroma.Dr Bruno Di Muzio and Dr Maxime St-Amant et al. Radiopaedia.org 2015. http://radiopaedia.org/articles/neurofibroma Accessed on November 17, 2015

@@ Line 6: / Line 6: @@
 ==MRI==
-* [[MRI]] may be helpful in the diagnosis of neurofibroma.
+* [[MRI]] may be helpful in the diagnosis of neurofibroma
 * MRI signal characteristics include:<ref name="radio">Neurofibroma.Dr Bruno Di Muzio and Dr Maxime St-Amant et al. Radiopaedia.org 2015. http://radiopaedia.org/articles/neurofibroma Accessed on November 17, 2015 </ref>
 {| class="wikitable"
@@ Line 17: / Line 17: @@
 * Hypointense
 * Homogeneous low signal intensity
+* Center demonstrating a higher signal intensity than the periphery (reverse of target sign on T2)
 |-
 |'''T2'''
@@ Line 22: / Line 23: @@
 * Hyperintense
 * Homogeneous high signal intensity (higher than fat)
+* Target sign (low signal intensity centrally with a ring of high signal intensity peripherally) in case of plexiform neurofibromas
+* Plexiform neurofibromas may appear as a larger and more infiltrating mass with lobulated borders with inhomogeneous enhancement
+* Myxoid stroma enhancement helps differentiating the high signal intensity at T2-weighted imaging from cystic change or necrosis
 |-
 |'''T1 with gadolinium contrast'''