Proteus syndrome: Difference between revisions
Jump to navigation
Jump to search
No edit summary |
|||
| Line 11: | Line 11: | ||
=== Discovery === | === Discovery === | ||
* Proteus syndrome was first discovered by Frederick Treves, a British surgeon, in 1884. | * Proteus syndrome was first discovered by Frederick Treves, a British surgeon, in 1884.<ref name="pmid3092979">{{cite journal |vauthors=Tibbles JA, Cohen MM |title=The Proteus syndrome: the Elephant Man diagnosed |journal=Br Med J (Clin Res Ed) |volume=293 |issue=6548 |pages=683–5 |date=September 1986 |pmid=3092979 |pmc=1341524 |doi= |url=}}</ref> | ||
* Frederick Treves showed the proteus syndrome on Joseph Merrick, who used to be called as the famous Elephant Man, to the Pathological Society of London. | * Frederick Treves showed the proteus syndrome on Joseph Merrick, who used to be called as the famous Elephant Man, to the Pathological Society of London. | ||
* | * | ||
Revision as of 20:07, 27 March 2019
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Vamsikrishna Gunnam M.B.B.S [2]
Synonyms and keywords:PS
Overview
Proteus syndrome is an exceedingly rare disorder which falls under the category of hamartomatous disorder. Proteus syndrome is a very complex disorder which involves multiple organ systems in the body.
Historical Perspective
Discovery
- Proteus syndrome was first discovered by Frederick Treves, a British surgeon, in 1884.[1]
- Frederick Treves showed the proteus syndrome on Joseph Merrick, who used to be called as the famous Elephant Man, to the Pathological Society of London.
Classification
- Proteus syndrome is one of the syndromes which falls under PTEN hamartoma tumor syndromes (PHTS). PHTS are due to germline mutations in PTEN gene.
- PTEN hamartoma tumor syndromes (PHTS) which include the following: