Breast cancer MRI: Difference between revisions
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==Overview== | ==Overview== | ||
MRI | Although a number of breast MRI indications remained controversial, breast MRI has been recommended for a variety of conditions such as studying a probable occult primary breast cancers, evaluation of disease extension, watching up the response to neoadjuvant chemotherapy, studying disease recurrence, as an adjuvant method to clarify inconclusive clinical or imaging findings, and as the recommended method of screening for high risk patients another indication of breast MRI is assessment of silicone implant integrity. | ||
==Findings on MRI== | ==Findings on MRI== | ||
MRI uses powerful magnetic forces and radio-frequency waves to make cross-sectional images of organs, tissues, bones and blood vessels. A computer turns the images into 3-dimensional pictures. An MRI of the breast is not routinely used to diagnose breast cancer, but may be done in certain situations to:<ref name="ss">Breast cancer. Canadian Cancer Society (2015) http://www.cancer.ca/en/cancer-information/cancer-type/breast/signs-and-symptoms/?region=on#ixzz3xScycfqv Accessed on January 16, 2016</ref> | MRI uses powerful magnetic forces and radio-frequency waves to make cross-sectional images of organs, tissues, bones and blood vessels. A computer turns the images into 3-dimensional pictures. An MRI of the breast is not routinely used to diagnose breast cancer, but may be done in certain situations to:<ref name="ss">Breast cancer. Canadian Cancer Society (2015) http://www.cancer.ca/en/cancer-information/cancer-type/breast/signs-and-symptoms/?region=on#ixzz3xScycfqv Accessed on January 16, 2016</ref> | ||
* | *Find the primary tumor in the breast | ||
:*MRI may be used if cancer is found in the axillary lymph nodes or if a woman has Paget disease of the nipple. | :*MRI may be used if cancer is found in the axillary lymph nodes or if a woman has Paget disease of the nipple. | ||
* | *Fnd out the extent of cancer in the breast tissue (local disease) | ||
:*MRI may be used when test results from physical examination, mammography or ultrasound are not clear. | :*MRI may be used when test results from physical examination, mammography or ultrasound are not clear. | ||
* | *Better examine an abnormality found on mammography | ||
:*MRI may be used if the abnormality cannot be found with other tests, such as a clinical breast exam or breast ultrasound. | :*MRI may be used if the abnormality cannot be found with other tests, such as a clinical breast exam or breast ultrasound. | ||
:*It may also be used if the abnormality can be seen from only one view of the results of a mammography. | :*It may also be used if the abnormality can be seen from only one view of the results of a mammography. | ||
* | *Check the condition of breast implants, especially if the doctor suspects that an implant has ruptured | ||
Breast MRI may be used to study silicone implant integrity. | Breast MRI may be used to study silicone implant integrity. | ||
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There is an overlap in the enhancement pattern of benign and malignant lesions. | There is an overlap in the enhancement pattern of benign and malignant lesions. | ||
The accuracy of breast MRI might be affected by hormonal changes and cancer treatment. | |||
Breast MRI either with or without contrast is contraindicated in: | |||
Pregnancy | |||
Implanted devices and foreign bodies (exception is MRI friendly implants | |||
History of gadolinium allergy | |||
Decreased renal function | |||
Although a number of breast MRI indications remained controversial, breast MRI has been recommended for a variety of conditions such as studying a probable occult primary breast cancers, evaluation of disease extension, watching up the response to neoadjuvant chemotherapy, disease recurrence, as an adjuvant method to clarify inconclusive clinical or imaging findings, and as the recommended method of screening for high risk patients another indication of breast MRI is assessment of silicone implant integrity. | |||
==References== | ==References== | ||
Revision as of 14:40, 9 April 2019
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Breast cancer MRI On the Web |
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American Roentgen Ray Society Images of Breast cancer MRI |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]{AE}} Mirdula Sharma, MBBS [2]
Overview
Although a number of breast MRI indications remained controversial, breast MRI has been recommended for a variety of conditions such as studying a probable occult primary breast cancers, evaluation of disease extension, watching up the response to neoadjuvant chemotherapy, studying disease recurrence, as an adjuvant method to clarify inconclusive clinical or imaging findings, and as the recommended method of screening for high risk patients another indication of breast MRI is assessment of silicone implant integrity.
Findings on MRI
MRI uses powerful magnetic forces and radio-frequency waves to make cross-sectional images of organs, tissues, bones and blood vessels. A computer turns the images into 3-dimensional pictures. An MRI of the breast is not routinely used to diagnose breast cancer, but may be done in certain situations to:[1]
- Find the primary tumor in the breast
- MRI may be used if cancer is found in the axillary lymph nodes or if a woman has Paget disease of the nipple.
- Fnd out the extent of cancer in the breast tissue (local disease)
- MRI may be used when test results from physical examination, mammography or ultrasound are not clear.
- Better examine an abnormality found on mammography
- MRI may be used if the abnormality cannot be found with other tests, such as a clinical breast exam or breast ultrasound.
- It may also be used if the abnormality can be seen from only one view of the results of a mammography.
- Check the condition of breast implants, especially if the doctor suspects that an implant has ruptured
Breast MRI may be used to study silicone implant integrity.
Tumor angiogenesis or neovascularity makes the foundation of application of MRI to detect breast cancer
Increased vasculture and hence increased permeability, increase take up and release of the contrast media and distinguish breast cancers from benign tumors
Tailored breast coil is essential for breast MRI.
application of contrast agents such as intravenous gadolinium is recommended in order to maximize cancer detection and to highlight neovascularity.
Evaluating silicone implant integrity. does not need contrast media.
Application of contrast media such as gadolinium is contraindicated in patients with renal function.
Breast MRI sensitivity is high, but the specificity is low
There is an overlap in the enhancement pattern of benign and malignant lesions.
The accuracy of breast MRI might be affected by hormonal changes and cancer treatment.
Breast MRI either with or without contrast is contraindicated in:
Pregnancy
Implanted devices and foreign bodies (exception is MRI friendly implants
History of gadolinium allergy
Decreased renal function
Although a number of breast MRI indications remained controversial, breast MRI has been recommended for a variety of conditions such as studying a probable occult primary breast cancers, evaluation of disease extension, watching up the response to neoadjuvant chemotherapy, disease recurrence, as an adjuvant method to clarify inconclusive clinical or imaging findings, and as the recommended method of screening for high risk patients another indication of breast MRI is assessment of silicone implant integrity.
References
- ↑ Breast cancer. Canadian Cancer Society (2015) http://www.cancer.ca/en/cancer-information/cancer-type/breast/signs-and-symptoms/?region=on#ixzz3xScycfqv Accessed on January 16, 2016