Retinoblastoma historical perspective: Difference between revisions
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{{Retinoblastoma}} | {{Retinoblastoma}} | ||
==Overview== | ==Overview== | ||
Retinoblastoma was first described in 1809 by James Wardrop. | Retinoblastoma was first described in 1809 by James Wardrop. | ||
==Historical Perspective == | ==Historical Perspective == | ||
*In | *In 1657, Dr. Petrus Pawius, an anatomist from Amesterdam, described a tumor resembling retinoblastoma for the first time.<ref name="Albert1987">{{cite journal|last1=Albert|first1=Daniel M.|title=Historic Review of Retinoblastoma|journal=Ophthalmology|volume=94|issue=6|year=1987|pages=654–662|issn=01616420|doi=10.1016/S0161-6420(87)33407-4}}</ref> | ||
*In 1809, Dr. James Wardrop, Scottish surgeon and ophthalmologist, first described the retinoblastoma tumor. | |||
*In 1971, Dr. Knudson proposed the two-hit hypothesis which give the light to the pathogenesis of the familial and sporadic form of the tumor.<ref name="pmid5279523">{{cite journal |vauthors=Knudson AG |title=Mutation and cancer: statistical study of retinoblastoma |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=68 |issue=4 |pages=820–3 |date=April 1971 |pmid=5279523 |pmc=389051 |doi= |url=}}</ref> | *In 1971, Dr. Knudson proposed the two-hit hypothesis which give the light to the pathogenesis of the familial and sporadic form of the tumor.<ref name="pmid5279523">{{cite journal |vauthors=Knudson AG |title=Mutation and cancer: statistical study of retinoblastoma |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=68 |issue=4 |pages=820–3 |date=April 1971 |pmid=5279523 |pmc=389051 |doi= |url=}}</ref> | ||
*In 1899, Flexner and Wintersteiner were the first to discover the association between tumor rosettes and photoreceptors of the adult retina. | *In 1899, Flexner and Wintersteiner were the first to discover the association between tumor rosettes and photoreceptors of the adult retina. | ||
*In 1920s Verhoeff claimed that the tumor arose from embryonic retinal cells and hence proposed the name "retinoblastoma". | *In 1920s Verhoeff claimed that the tumor arose from embryonic retinal cells and hence proposed the name "retinoblastoma". | ||
Revision as of 13:28, 19 April 2019
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Simrat Sarai, M.D. [2]
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Overview
Retinoblastoma was first described in 1809 by James Wardrop.
Historical Perspective
- In 1657, Dr. Petrus Pawius, an anatomist from Amesterdam, described a tumor resembling retinoblastoma for the first time.[1]
- In 1809, Dr. James Wardrop, Scottish surgeon and ophthalmologist, first described the retinoblastoma tumor.
- In 1971, Dr. Knudson proposed the two-hit hypothesis which give the light to the pathogenesis of the familial and sporadic form of the tumor.[2]
- In 1899, Flexner and Wintersteiner were the first to discover the association between tumor rosettes and photoreceptors of the adult retina.
- In 1920s Verhoeff claimed that the tumor arose from embryonic retinal cells and hence proposed the name "retinoblastoma".
References
- ↑ Albert, Daniel M. (1987). "Historic Review of Retinoblastoma". Ophthalmology. 94 (6): 654–662. doi:10.1016/S0161-6420(87)33407-4. ISSN 0161-6420.
- ↑ Knudson AG (April 1971). "Mutation and cancer: statistical study of retinoblastoma". Proc. Natl. Acad. Sci. U.S.A. 68 (4): 820–3. PMC 389051. PMID 5279523.