Glomus tumor other diagnostic studies: Difference between revisions
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***CD34 (rarely positive) | ***CD34 (rarely positive) | ||
***S100 | ***S100 | ||
* Clinical Tests | * Clinical Tests: | ||
** '''Love test''' | ** '''Love test'''<ref name="pmid15215032">{{cite journal| author=Pater TJ, Marks RM| title=Glomus tumor of the hallux: case presentation and review of the literature. | journal=Foot Ankle Int | year= 2004 | volume= 25 | issue= 6 | pages= 434-7 | pmid=15215032 | doi=10.1177/107110070402500614 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=15215032 }}</ref> | ||
*** Orientative | *** Orientative | ||
*** Probing with a needle or pointed instrument triggers pain in the affected area but not the area immediately adjacent to it | *** Probing with a needle or pointed instrument triggers pain in the affected area but not the area immediately adjacent to it | ||
*** Sensitivity= 100% | *** Sensitivity= 100% | ||
*** Specificity= 0% | *** Specificity= 0% | ||
** '''Hildreth sign''' | ** '''Hildreth sign'''<ref name="pmid15215032" /> | ||
*** Occurence of pain following induction of ischemia by application of a tourniquet to the glomus tumor mimicking median nail dystrophy (the longitudinal splitting in the midline of the nail) | *** Occurence of pain following induction of ischemia by application of a tourniquet to the glomus tumor mimicking median nail dystrophy (the longitudinal splitting in the midline of the nail) | ||
*** Highlights the vascular nature of the lesion | *** Highlights the vascular nature of the lesion | ||
*** Sensitivity= 77.4% - 92% | *** Sensitivity= 77.4% - 92% | ||
*** Specificity= 91% - 100% | *** Specificity= 91% - 100% | ||
** '''Cold-sensitivity test''' | ** '''Cold-sensitivity test'''<ref name="pmid15215032" /> | ||
*** Application of cold water or ethanol to the affected area reproducing the symptoms | *** Application of cold water or ethanol to the affected area reproducing the symptoms | ||
*** Sensitivity= 100% | *** Sensitivity= 100% | ||
Revision as of 23:44, 6 May 2019
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Glomus tumor Microchapters |
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Glomus tumor other diagnostic studies On the Web |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Soujanya Thummathati, MBBS [2]
Overview
Other diagnostic studies for glomus tumor include immunohistochemistry staining, which demonstrates glomus cells positive for vimentin and alpha-smooth muscle actin and negative for desmin.[1]
Other Diagnostic Studies
- Other diagnostic studies for glomus tumor include immunohistochemistry staining, which demonstrates the following:[1]
- Clinical Tests:
- Love test[2]
- Orientative
- Probing with a needle or pointed instrument triggers pain in the affected area but not the area immediately adjacent to it
- Sensitivity= 100%
- Specificity= 0%
- Hildreth sign[2]
- Occurence of pain following induction of ischemia by application of a tourniquet to the glomus tumor mimicking median nail dystrophy (the longitudinal splitting in the midline of the nail)
- Highlights the vascular nature of the lesion
- Sensitivity= 77.4% - 92%
- Specificity= 91% - 100%
- Cold-sensitivity test[2]
- Application of cold water or ethanol to the affected area reproducing the symptoms
- Sensitivity= 100%
- Specificity= 100%
- Transillumination test
- Performed in a darkened room by passing light through the finger pad
- An opaque red image is observed in the region of the tumor that allows estimation of its size
- Sensitivity= 23% - 38%
- Specificity= 90%
- Love test[2]
References
- ↑ 1.0 1.1 Kaye VM, Dehner LP (1991). "Cutaneous glomus tumor. A comparative immunohistochemical study with pseudoangiomatous intradermal melanocytic nevi". Am J Dermatopathol. 13 (1): 2–6. PMID 1848411.
- ↑ 2.0 2.1 2.2 Pater TJ, Marks RM (2004). "Glomus tumor of the hallux: case presentation and review of the literature". Foot Ankle Int. 25 (6): 434–7. doi:10.1177/107110070402500614. PMID 15215032.