Neoplastic meningitis: Difference between revisions
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==[[Neoplastic meningitis classification|Classification]]== | ==[[Neoplastic meningitis classification|Classification]]== | ||
==[[Neoplastic meningitis pathophysiology|Pathophysiology]]== | ==[[Neoplastic meningitis pathophysiology|Pathophysiology]]== | ||
* The pathophysiology of neoplastic meningitis involves spread of cancer cells to the meninges and subarachnoid space. The location could be the brain or the spinal cord. It could be from a distant source or from a primary CNS tumor (drop metastasis. | |||
* Cancer from a distant source enter the CSF by means of the following:[https://en.wikipedia.org/wiki/Neoplastic_meningitis] | |||
** Hematogenous Spread - cancer cells invade blood vessels to reach the subarachnoid space through the systemic arterial circulation or by the Batsons venous plexus. | |||
** Infiltration to the spinal cord - | |||
** | |||
==[[Neoplastic meningitis causes|Causes]]== | ==[[Neoplastic meningitis causes|Causes]]== | ||
* | * Neoplastic meningitis is a secondary cancer caused by the spread of tumor cells into the meninges and subarachnoid space from a primary source. Most common sources documented are breast, lung, melanoma and hematologic cancers mostly acute lymphocytic leukemia.[https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4093424/] | ||
==[[Neoplastic meningitis differential diagnosis|Differentiating Neoplastic Meningitis from other Diseases]]== | ==[[Neoplastic meningitis differential diagnosis|Differentiating Neoplastic Meningitis from other Diseases]]== | ||
Revision as of 04:47, 12 May 2019
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Neoplastic meningitis Microchapters |
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Diagnosis |
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Treatment |
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Case Studies |
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Neoplastic meningitis On the Web |
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American Roentgen Ray Society Images of Neoplastic meningitis |
For patient information, click here
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Sujit Routray, M.D. [2]
Synonyms and keywords: NM; Carcinomatous meningitis; Leptomeningeal carcinomatosis; LC; Neoplastic arachnoiditis; Malignant meningitis; Leptomeningeal neoplasia, Meningeal carcinomatosis; Meningeosis neoplastica; Meningitis carcinomatosa; Leptomeningeal metastasis; Leptomeningeal metastases; Carcinomatous meningitis; Subarachnoid space metastasis; Subarachnoid space metastases
Overview
Historical Perspective
Classification
Pathophysiology
- The pathophysiology of neoplastic meningitis involves spread of cancer cells to the meninges and subarachnoid space. The location could be the brain or the spinal cord. It could be from a distant source or from a primary CNS tumor (drop metastasis.
- Cancer from a distant source enter the CSF by means of the following:[3]
- Hematogenous Spread - cancer cells invade blood vessels to reach the subarachnoid space through the systemic arterial circulation or by the Batsons venous plexus.
- Infiltration to the spinal cord -
Causes
- Neoplastic meningitis is a secondary cancer caused by the spread of tumor cells into the meninges and subarachnoid space from a primary source. Most common sources documented are breast, lung, melanoma and hematologic cancers mostly acute lymphocytic leukemia.[4]
Differentiating Neoplastic Meningitis from other Diseases
Epidemiology and Demographics
Risk Factors
Screening
Natural History, Complications and Prognosis
Diagnosis
Staging | History and Symptoms | Physical Examination | Laboratory Findings | CT | MRI | Other Imaging Findings | Other Diagnostic Studies
Treatment
Medical Therapy | Surgery | Prevention | Cost-Effectiveness of Therapy | Future or Investigational Therapies