Familial mediterranean fever epidemiology and demographics: Difference between revisions

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*[[Patients]] of all age groups may develop the [[Familial mediterranean fever|familial Mediterranean fever]] ([[FMF]]). However, it usually manifests during Childhood.<ref name="KallinichAktay2015">{{cite journal|last1=Kallinich|first1=Tilmann|last2=Aktay|first2=Nuray|last3=Ozen|first3=Seza|title=Special Aspects of Familial Mediterranean Fever in Childhood|volume=3|year=2015|pages=31–45|issn=2282-6505|doi=10.1007/978-3-319-14615-7_3}}</ref>
*[[Patients]] of all age groups may develop the [[Familial mediterranean fever|familial Mediterranean fever]] ([[FMF]]). However, it usually manifests during Childhood.<ref name="KallinichAktay2015">{{cite journal|last1=Kallinich|first1=Tilmann|last2=Aktay|first2=Nuray|last3=Ozen|first3=Seza|title=Special Aspects of Familial Mediterranean Fever in Childhood|volume=3|year=2015|pages=31–45|issn=2282-6505|doi=10.1007/978-3-319-14615-7_3}}</ref>
*90% of the individuals present the [[symptoms]] before the age of 20 years.
*90% of the individuals present the [[symptoms]] before the age of 20 years.
*Only 1% of individuals present the first [[symptoms]] after the 40 years of age.<ref name="pmid10528243">{{cite journal |vauthors=Tamir N, Langevitz P, Zemer D, Pras E, Shinar Y, Padeh S, Zaks N, Pras M, Livneh A |title=Late-onset familial Mediterranean fever (FMF): a subset with distinct clinical, demographic, and molecular genetic characteristics |journal=Am. J. Med. Genet. |volume=87 |issue=1 |pages=30–5 |date=November 1999 |pmid=10528243 |doi= |url=}}</ref> However, this may vary according to the area of the study.<ref name="pmid31116049">{{cite journal |vauthors=Kishida D, Yazaki M, Nakamura A, Tsuchiya-Suzuki A, Shimojima Y, Sekijima Y |title=Late-onset familial Mediterranean fever in Japan |journal=Mod Rheumatol |volume= |issue= |pages=1–11 |date=May 2019 |pmid=31116049 |doi=10.1080/14397595.2019.1621440 |url=}}</ref>
*Only 1% of individuals present the first [[symptoms]] after the 40 years of age.<ref name="pmid10528243">{{cite journal |vauthors=Tamir N, Langevitz P, Zemer D, Pras E, Shinar Y, Padeh S, Zaks N, Pras M, Livneh A |title=Late-onset familial Mediterranean fever (FMF): a subset with distinct clinical, demographic, and molecular genetic characteristics |journal=Am. J. Med. Genet. |volume=87 |issue=1 |pages=30–5 |date=November 1999 |pmid=10528243 |doi= |url=}}</ref> However, this may vary according to the geographical area of the study.<ref name="pmid31116049">{{cite journal |vauthors=Kishida D, Yazaki M, Nakamura A, Tsuchiya-Suzuki A, Shimojima Y, Sekijima Y |title=Late-onset familial Mediterranean fever in Japan |journal=Mod Rheumatol |volume= |issue= |pages=1–11 |date=May 2019 |pmid=31116049 |doi=10.1080/14397595.2019.1621440 |url=}}</ref>


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Revision as of 19:32, 23 May 2019

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:

Overview

Epidemiology and Demographics

Incidence

  • The incidence/prevalence of [disease name] is approximately [number range] per 100,000 individuals worldwide.

Prevalence

  • The incidence/prevalence of [disease name] is approximately [number range] per 100,000 individuals worldwide.

Age

  • Patients of all age groups may develop the familial Mediterranean fever (FMF). However, it usually manifests during Childhood.[1]
  • 90% of the individuals present the symptoms before the age of 20 years.
  • Only 1% of individuals present the first symptoms after the 40 years of age.[2] However, this may vary according to the geographical area of the study.[3]

Race

  • FMF usually affects individuals of the Turkish, Armenian, Jewish and Arabic communities.[4]

Gender

  • FMF affects men and women equally. However, recent studies showed a slight male preponderance.[5]

Region

  • The majority of FMF cases are reported among the nations of the Mediterranean region.[4]
  • This disorder is most commonly seen in Turkey, followed by Armenia.[6][7]

Developed Countries

Developing Countries

References

  1. Kallinich, Tilmann; Aktay, Nuray; Ozen, Seza (2015). "Special Aspects of Familial Mediterranean Fever in Childhood". 3: 31–45. doi:10.1007/978-3-319-14615-7_3. ISSN 2282-6505.
  2. Tamir N, Langevitz P, Zemer D, Pras E, Shinar Y, Padeh S, Zaks N, Pras M, Livneh A (November 1999). "Late-onset familial Mediterranean fever (FMF): a subset with distinct clinical, demographic, and molecular genetic characteristics". Am. J. Med. Genet. 87 (1): 30–5. PMID 10528243.
  3. Kishida D, Yazaki M, Nakamura A, Tsuchiya-Suzuki A, Shimojima Y, Sekijima Y (May 2019). "Late-onset familial Mediterranean fever in Japan". Mod Rheumatol: 1–11. doi:10.1080/14397595.2019.1621440. PMID 31116049.
  4. 4.0 4.1 Cerrito, Lucia; Sicignano, Ludovico Luca; Verrecchia, Elena; Manna, Raffaele (2015). "Epidemiology of FMF Worldwide". 3: 81–90. doi:10.1007/978-3-319-14615-7_5. ISSN 2282-6505.
  5. Tunca M, Akar S, Onen F, Ozdogan H, Kasapcopur O, Yalcinkaya F, Tutar E, Ozen S, Topaloglu R, Yilmaz E, Arici M, Bakkaloglu A, Besbas N, Akpolat T, Dinc A, Erken E (January 2005). "Familial Mediterranean fever (FMF) in Turkey: results of a nationwide multicenter study". Medicine (Baltimore). 84 (1): 1–11. PMID 15643295.
  6. Kisacik B, Yildirim B, Tasliyurt T, Ozyurt H, Ozyurt B, Yuce S, Kaya S, Ertenli I, Kiraz S (September 2009). "Increased frequency of familial Mediterranean fever in northern Turkey: a population-based study". Rheumatol. Int. 29 (11): 1307–9. doi:10.1007/s00296-009-0849-z. PMID 19152093.
  7. Sarkisian T, Ajrapetian H, Beglarian A, Shahsuvarian G, Egiazarian A (March 2008). "Familial Mediterranean Fever in Armenian population". Georgian Med News (156): 105–11. PMID 18403822.

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