Palmar plantar erythrodysesthesia causes: Difference between revisions
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'''Most frequently associated:''' | '''Most frequently associated:''' | ||
* Cytarabine< | * Cytarabine (Cytosar-U) <ref name="pmid3977204">{{cite journal| author=Baer MR, King LE, Wolff SN| title=Palmar-plantar erythrodysesthesia and cytarabine. | journal=Ann Intern Med | year= 1985 | volume= 102 | issue= 4 | pages= 556 | pmid=3977204 | doi=10.7326/0003-4819-102-4-556_1 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=3977204 }} </ref> <ref name="pmid12460237">{{cite journal| author=Crawford JH, Eikelboom JW, McQuillan A| title=Recurrent palmar-plantar erythrodysaesthesia following high-dose cytarabine treatment for acute lymphoblastic leukemia. | journal=Eur J Haematol | year= 2002 | volume= 69 | issue= 5-6 | pages= 315-7 | pmid=12460237 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=12460237 }} </ref> | ||
* Docetaxel< | * Docetaxel(Docefrez, Taxotere) <ref name="pmid7857119">{{cite journal| author=Zimmerman GC, Keeling JH, Burris HA, Cook G, Irvin R, Kuhn J et al.| title=Acute cutaneous reactions to docetaxel, a new chemotherapeutic agent. | journal=Arch Dermatol | year= 1995 | volume= 131 | issue= 2 | pages= 202-6 | pmid=7857119 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=7857119 }} </ref> <ref name="pmid15187308">{{cite journal| author=Katoh M, Kadota M, Nishimura Y| title=A case of docetaxel-induced erythrodysesthesia. | journal=J Dermatol | year= 2004 | volume= 31 | issue= 5 | pages= 403-6 | pmid=15187308 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=15187308 }} </ref> | ||
* Doxorubicin (Adriamycin)<sup>17,18</sup> and liposomal-encapsulated doxorubicin<sup>19-25</sup> (Doxil) | * Doxorubicin (Adriamycin)<sup>17,18</sup> and liposomal-encapsulated doxorubicin<sup>19-25</sup> (Doxil) | ||
* 5-Fluorouracil<sup>26-41</sup> (5-FU, Adrucil) | * 5-Fluorouracil<sup>26-41</sup> (5-FU, Adrucil) | ||
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===Genetics=== | ===Genetics=== | ||
No genetic association has been found as of yet as the data on this condition is limited. | No genetic association has been found as of yet as the data on this condition is limited. | ||
==References== | ==References== | ||
{{reflist|2}} | {{reflist|2}} |
Revision as of 13:59, 27 June 2019
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Several different Chemotherapeutic agents have been associated with acral erythema[1]
Causes
Chemotherapy drugs that can cause this syndrome include:
Most frequently associated:
- Cytarabine (Cytosar-U) [2] [3]
- Docetaxel(Docefrez, Taxotere) [4] [5]
- Doxorubicin (Adriamycin)17,18 and liposomal-encapsulated doxorubicin19-25 (Doxil)
- 5-Fluorouracil26-41 (5-FU, Adrucil)
- Capecitabine8,42-47 (Xeloda)
- Sorafenib [6]
Less frequently associated:
- Cisplatin48
- Cyclophosphamide49
- Daunorubicin and liposomal daunorubicin50
- Doxifluridine
- Etoposide51-54
- Floxuridine55 (FUDF)
- Hydroxyurea56,57 (hydroxycarbamide)
- 6-Mercaptopurine9
- Methotrexate58-63
- Mitotane1
- Paclitaxel64-67 (Taxol)
- Tegafur68-70
- Vinorelbine71-74
- Idarubicin (Idamycin)
- Vemurafenib75 (Zelboraf)
- 6-thioguanine76
Commonly associated chemotherapeutic agents are listed below:
- Most frequently associated with Doxorubicin (Pegylated liposomal Doxorubicin), 5-Flurouracil, and Cytarabine[7].
- Methotrexate - even low dose used to treat ALL[8]
- Mitotane[9]
- PLD, Docetaxel, Capecitabine, vinorelbine, gemcitabine and Sorafenib[6]
Less Common Causes[10]
- Cisplatin
- Cyclophosphamide
- Daunorubicin
- Doxifluridine
- Etoposide
- Floxuridine
- Hydroxyurea
- Idarubicin
- Lomustine
- Melphalan
- Mercaptopurine
- Mitomycin
- Paclitaxel
- Suramin
- Troxacitabine[11]
- Tegafur
- Vincristine
Genetics
No genetic association has been found as of yet as the data on this condition is limited.
References
- ↑ Baack BR, Burgdorf WH (1991). "Chemotherapy-induced acral erythema". J Am Acad Dermatol. 24 (3): 457–61. PMID 2061446.
- ↑ Baer MR, King LE, Wolff SN (1985). "Palmar-plantar erythrodysesthesia and cytarabine". Ann Intern Med. 102 (4): 556. doi:10.7326/0003-4819-102-4-556_1. PMID 3977204.
- ↑ Crawford JH, Eikelboom JW, McQuillan A (2002). "Recurrent palmar-plantar erythrodysaesthesia following high-dose cytarabine treatment for acute lymphoblastic leukemia". Eur J Haematol. 69 (5–6): 315–7. PMID 12460237.
- ↑ Zimmerman GC, Keeling JH, Burris HA, Cook G, Irvin R, Kuhn J; et al. (1995). "Acute cutaneous reactions to docetaxel, a new chemotherapeutic agent". Arch Dermatol. 131 (2): 202–6. PMID 7857119.
- ↑ Katoh M, Kadota M, Nishimura Y (2004). "A case of docetaxel-induced erythrodysesthesia". J Dermatol. 31 (5): 403–6. PMID 15187308.
- ↑ 6.0 6.1 Farr KP, Safwat A (2011). "Palmar-plantar erythrodysesthesia associated with chemotherapy and its treatment". Case Rep Oncol. 4 (1): 229–35. doi:10.1159/000327767. PMC 3085037. PMID 21537373.
- ↑ Webster-Gandy JD, How C, Harrold K (2007). "Palmar-plantar erythrodysesthesia (PPE): a literature review with commentary on experience in a cancer centre". Eur J Oncol Nurs. 11 (3): 238–46. doi:10.1016/j.ejon.2006.10.004. PMID 17350337.
- ↑ Wysocki M, Nowaczyk-Michalak A, Pilecki O, Kurylak A, Balcar-Boroń A, Trybuś L (1992). "[Burgdorf's reaction (painful acral erythema) in patients with acute lymphoblastic leukemia following medium-dose methotrexate therapy]". Wiad Lek. 45 (11–12): 462–4. PMID 1441532.
- ↑ Zuehlke RL (1974). "Erythematous eruption of the palms and soles associated with mitotane therapy". Dermatologica. 148 (2): 90–2. PMID 4276191.
- ↑ Susser WS, Whitaker-Worth DL, Grant-Kels JM (1999). "Mucocutaneous reactions to chemotherapy". J Am Acad Dermatol. 40 (3): 367–98, quiz 399-400. PMID 10071309.
- ↑ Hidalgo M, Siu LL, Nemunaitis J, Rizzo J, Hammond LA, Takimoto C; et al. (2001). "Phase I and pharmacologic study of OSI-774, an epidermal growth factor receptor tyrosine kinase inhibitor, in patients with advanced solid malignancies". J Clin Oncol. 19 (13): 3267–79. doi:10.1200/JCO.2001.19.13.3267. PMID 11432895.