Palmar plantar erythrodysesthesia history and symptoms: Difference between revisions
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==History and Symptoms== | ==History and Symptoms== | ||
=== Common Symptoms === | |||
The most common symptoms of PPE include: | The most common symptoms of PPE include: | ||
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* The palms of the hands are usually more frequently and more severely affected than the soles of the feet, and may be only are affected.<ref name="pmid2061446">{{cite journal| author=Baack BR, Burgdorf WH| title=Chemotherapy-induced acral erythema. | journal=J Am Acad Dermatol | year= 1991 | volume= 24 | issue= 3 | pages= 457-61 | pmid=2061446 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=2061446 }} </ref> <ref name="pmid15341880">{{cite journal| author=Lassere Y, Hoff P| title=Management of hand-foot syndrome in patients treated with capecitabine (Xeloda). | journal=Eur J Oncol Nurs | year= 2004 | volume= 8 Suppl 1 | issue= | pages= S31-40 | pmid=15341880 | doi=10.1016/j.ejon.2004.06.007 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=15341880 }} </ref> | * The palms of the hands are usually more frequently and more severely affected than the soles of the feet, and may be only are affected.<ref name="pmid2061446">{{cite journal| author=Baack BR, Burgdorf WH| title=Chemotherapy-induced acral erythema. | journal=J Am Acad Dermatol | year= 1991 | volume= 24 | issue= 3 | pages= 457-61 | pmid=2061446 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=2061446 }} </ref> <ref name="pmid15341880">{{cite journal| author=Lassere Y, Hoff P| title=Management of hand-foot syndrome in patients treated with capecitabine (Xeloda). | journal=Eur J Oncol Nurs | year= 2004 | volume= 8 Suppl 1 | issue= | pages= S31-40 | pmid=15341880 | doi=10.1016/j.ejon.2004.06.007 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=15341880 }} </ref> | ||
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=== Less Common Symptoms === | |||
Less common symptoms include: <ref name="pmid11034047">{{cite journal| author=Hui YF, Cortes JE| title=Palmar-plantar erythrodysesthesia syndrome associated with liposomal daunorubicin. | journal=Pharmacotherapy | year= 2000 | volume= 20 | issue= 10 | pages= 1221-3 | pmid=11034047 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=11034047 }} </ref> <ref name="urlwww.oncologynurseadvisor.com">{{cite web |url=https://www.oncologynurseadvisor.com/home/departments/ce-courses/prevention-and-management-of-hand-foot-syndromes/ |title=www.oncologynurseadvisor.com |format= |work= |accessdate=}}</ref> | |||
* Sensory impairment | * Sensory impairment | ||
| Line 34: | Line 39: | ||
* A bullous variant (a severe form of this entity) specifically occurs with cytarabine or methotrexate.<ref name="pmid8624164">{{cite journal| author=Hellier I, Bessis D, Sotto A, Margueritte G, Guilhou JJ| title=High-dose methotrexate-induced bullous variant of acral erythema. | journal=Arch Dermatol | year= 1996 | volume= 132 | issue= 5 | pages= 590-1 | pmid=8624164 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=8624164 }} </ref><ref name="pmid8420487">{{cite journal| author=Waltzer JF, Flowers FP| title=Bullous variant of chemotherapy-induced acral erythema. | journal=Arch Dermatol | year= 1993 | volume= 129 | issue= 1 | pages= 43-5 | pmid=8420487 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=8420487 }} </ref> | * A bullous variant (a severe form of this entity) specifically occurs with cytarabine or methotrexate.<ref name="pmid8624164">{{cite journal| author=Hellier I, Bessis D, Sotto A, Margueritte G, Guilhou JJ| title=High-dose methotrexate-induced bullous variant of acral erythema. | journal=Arch Dermatol | year= 1996 | volume= 132 | issue= 5 | pages= 590-1 | pmid=8624164 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=8624164 }} </ref><ref name="pmid8420487">{{cite journal| author=Waltzer JF, Flowers FP| title=Bullous variant of chemotherapy-induced acral erythema. | journal=Arch Dermatol | year= 1993 | volume= 129 | issue= 1 | pages= 43-5 | pmid=8420487 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=8420487 }} </ref> | ||
Involvement of other parts of the body is rare, even though mild erythema or morbilliform lesions might occasionally be seen on the trunk, trunk, neck, chest, scalp and | Involvement of other parts of the body is rare, even though mild erythema or morbilliform lesions might occasionally be seen on the trunk, trunk, neck, chest, scalp and extremitirs. <ref name="pmid2061446">{{cite journal| author=Baack BR, Burgdorf WH| title=Chemotherapy-induced acral erythema. | journal=J Am Acad Dermatol | year= 1991 | volume= 24 | issue= 3 | pages= 457-61 | pmid=2061446 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=2061446 }} </ref> <ref name="pmid2528937">{{cite journal| author=Kroll SS, Koller CA, Kaled S, Dreizen S| title=Chemotherapy-induced acral erythema: desquamating lesions involving the hands and feet. | journal=Ann Plast Surg | year= 1989 | volume= 23 | issue= 3 | pages= 263-5 | pmid=2528937 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=2528937 }} </ref> | ||
=== | |||
==References== | ==References== | ||
{{reflist|2}} | {{reflist|2}} | ||
Revision as of 19:14, 27 June 2019
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:
Overview
The majority of patients with [disease name] are asymptomatic.
OR
The hallmark of [disease name] is [finding]. A positive history of [finding 1] and [finding 2] is suggestive of [disease name]. The most common symptoms of [disease name] include [symptom 1], [symptom 2], and [symptom 3]. Common symptoms of [disease] include [symptom 1], [symptom 2], and [symptom 3]. Less common symptoms of [disease name] include [symptom 1], [symptom 2], and [symptom 3].
History and Symptoms
Common Symptoms
The most common symptoms of PPE include:
- A prodrome of dysesthesia, usually as a tingling sensation in the fingers, palms and/or soles, progressing to a burning pain in a few days
- A well-defined edema and symmetrical erythema, more prominently over the fat pads of the distal phalanges
- Skip areas may be seen
- Extension to the dorsal surfaces of the extremities, or over joint surfaces can occur [1]
- Periungual skin involvement is also possible
- The palms of the hands are usually more frequently and more severely affected than the soles of the feet, and may be only are affected.[1] [2]
Less Common Symptoms
Less common symptoms include: [3] [4]
- Sensory impairment
- paresthesia
- pruritus
- A bullous variant (a severe form of this entity) specifically occurs with cytarabine or methotrexate.[5][6]
Involvement of other parts of the body is rare, even though mild erythema or morbilliform lesions might occasionally be seen on the trunk, trunk, neck, chest, scalp and extremitirs. [1] [7]
References
- ↑ 1.0 1.1 1.2 Baack BR, Burgdorf WH (1991). "Chemotherapy-induced acral erythema". J Am Acad Dermatol. 24 (3): 457–61. PMID 2061446.
- ↑ Lassere Y, Hoff P (2004). "Management of hand-foot syndrome in patients treated with capecitabine (Xeloda)". Eur J Oncol Nurs. 8 Suppl 1: S31–40. doi:10.1016/j.ejon.2004.06.007. PMID 15341880.
- ↑ Hui YF, Cortes JE (2000). "Palmar-plantar erythrodysesthesia syndrome associated with liposomal daunorubicin". Pharmacotherapy. 20 (10): 1221–3. PMID 11034047.
- ↑ "www.oncologynurseadvisor.com".
- ↑ Hellier I, Bessis D, Sotto A, Margueritte G, Guilhou JJ (1996). "High-dose methotrexate-induced bullous variant of acral erythema". Arch Dermatol. 132 (5): 590–1. PMID 8624164.
- ↑ Waltzer JF, Flowers FP (1993). "Bullous variant of chemotherapy-induced acral erythema". Arch Dermatol. 129 (1): 43–5. PMID 8420487.
- ↑ Kroll SS, Koller CA, Kaled S, Dreizen S (1989). "Chemotherapy-induced acral erythema: desquamating lesions involving the hands and feet". Ann Plast Surg. 23 (3): 263–5. PMID 2528937.