Palmar plantar erythrodysesthesia differential diagnosis: Difference between revisions
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| style="background: #DCDCDC; padding: 5px; text-align: left;" valign="top" | '''[[Palmar plantar erythrodysesthesia]]''' | | style="background: #DCDCDC; padding: 5px; text-align: left;" valign="top" | '''[[Palmar plantar erythrodysesthesia]]''' | ||
| style="background: #DCDCDC; padding: 5px; text-align: left;" valign="top" | | | style="background: #DCDCDC; padding: 5px; text-align: left;" valign="top" | | ||
* The areas of well-defined intense erythema and edema | * The areas of well-defined intense erythema and edema | ||
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* A variable degree of epidermal (keratinocytes) necrosis <ref name="pmid8468414">{{cite journal| author=Fitzpatrick JE| title=The cutaneous histopathology of chemotherapeutic reactions. | journal=J Cutan Pathol | year= 1993 | volume= 20 | issue= 1 | pages= 1-14 | pmid=8468414 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=8468414 }} </ref> | * A variable degree of epidermal (keratinocytes) necrosis <ref name="pmid8468414">{{cite journal| author=Fitzpatrick JE| title=The cutaneous histopathology of chemotherapeutic reactions. | journal=J Cutan Pathol | year= 1993 | volume= 20 | issue= 1 | pages= 1-14 | pmid=8468414 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=8468414 }} </ref> | ||
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* Papillary dermal edema | * Papillary dermal edema | ||
* Neutrophilic eccrine hidradenitis | * Neutrophilic eccrine hidradenitis | ||
* Eccrine squamous syringometaplasia, in severe PPE (WHO grades 3 and 4) | * Eccrine squamous syringometaplasia, in severe PPE (WHO grades 3 and 4)<ref name="pmid9236526">{{cite journal| author=Valks R, Fraga J, Porras-Luque J, Figuera A, Garcia-Diéz A, Fernändez-Herrera J| title=Chemotherapy-induced eccrine squamous syringometaplasia. A distinctive eruption in patients receiving hematopoietic progenitor cells. | journal=Arch Dermatol | year= 1997 | volume= 133 | issue= 7 | pages= 873-8 | pmid=9236526 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=9236526 }} </ref> | ||
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* History of chemotherapeutic agent use | * History of chemotherapeutic agent use |
Revision as of 16:24, 31 July 2019
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mandana Chitsazan, M.D. [2]
Overview
Palmar plantar erythrodysesthesia must be differentiated from other skin disorders that involve palms and/or soles, such as Graft-versus-host-disease, contact dermatitis, palmoplantar plaque psoriasis, dyshidrotic eczema, and palmoplantar pustulosis.
Differentiating palmar plantar erythrodysesthesia from other Diseases
Palmar plantar erythrodysesthesia must be differentiated from other skin disorders that involve palms and/or soles, such as Graft-versus-host-disease, contact dermatitis, palmoplantar plaque psoriasis, dyshidrotic eczema, and palmoplantar pustulosis.
Disease | Clinical manifestation | Histopathology | Additional diagnostic clues |
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Palmar plantar erythrodysesthesia |
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Graft-versus-host disease |
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Contact dermatitis |
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Palmoplantar plaque psoriasis |
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Dyshidrotic eczema |
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Palmoplantar pustulosis |
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References
- ↑ Fitzpatrick JE (1993). "The cutaneous histopathology of chemotherapeutic reactions". J Cutan Pathol. 20 (1): 1–14. PMID 8468414.
- ↑ Valks R, Fraga J, Porras-Luque J, Figuera A, Garcia-Diéz A, Fernändez-Herrera J (1997). "Chemotherapy-induced eccrine squamous syringometaplasia. A distinctive eruption in patients receiving hematopoietic progenitor cells". Arch Dermatol. 133 (7): 873–8. PMID 9236526.