Extranodal NK-T-cell lymphoma epidemiology and demographics: Difference between revisions
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* NK cell lymphoma shows a poor prognosis because of rapid local progression and distant metastasis. | * NK cell lymphoma shows a poor prognosis because of rapid local progression and distant metastasis. | ||
=== Age === | |||
* The median age of onset is approximately 50 years and it is common in elderly.<ref name="KoCho2004">{{cite journal|last1=Ko|first1=Y H|last2=Cho|first2=E-Y|last3=Kim|first3=J-E|last4=Lee|first4=S-S|last5=Huh|first5=J-R|last6=Chang|first6=H-K|last7=Yang|first7=W-I|last8=Kim|first8=C-W|last9=Kim|first9=S-W|last10=Ree|first10=H J|title=NK and NK-like T-cell lymphoma in extranasal sites: a comparative clinicopathological study according to site and EBV status|journal=Histopathology|volume=44|issue=5|year=2004|pages=480–489|issn=0309-0167|doi=10.1111/j.1365-2559.2004.01867.x}}</ref> | |||
* Extranodal NK/T-cell lymphoma is a rare disease in children and often it is associated with mosquito-bite hypersensetivity or other EBV-associated disease.<ref name="NgKhoury2009">{{cite journal|last1=Ng|first1=Siok-Bian|last2=Khoury|first2=Joseph D.|title=Epstein-Barr Virus in Lymphoproliferative Processes|journal=Advances in Anatomic Pathology|volume=16|issue=1|year=2009|pages=40–55|issn=1072-4109|doi=10.1097/PAP.0b013e3181916029}}</ref> | |||
=== Race === | === Race === | ||
* Natural Killer (NK) cell lymphoma is a rare disease. NK/T cell lymphoma, nasal type (NKTCL) and aggressive NK-cell leukemia (ANKCL) have a higher incidence in Asia, Central, and South America. | * Natural Killer (NK) cell lymphoma is a rare disease. NK/T cell lymphoma, nasal type (NKTCL) and aggressive NK-cell leukemia (ANKCL) have a higher incidence in Asia, Central, and South America. | ||
* Nk cell lymphoma is usually associated with Epstein-Barr virus infection. | * Nk cell lymphoma is usually associated with Epstein-Barr virus infection. | ||
=== Gender === | === Gender === | ||
* Extranodal NK/T-cell lymphoma shows male preponderance. | * Extranodal NK/T-cell lymphoma shows male preponderance. | ||
=== Region === | === Region === | ||
*NK T cell lymphoma, nasal type (NNKTL) consist 3000-10000 out of 100000 cases of non-Hodgkin lymphoma in Asia and South America and less than | *NK T cell lymphoma, nasal type (NNKTL) consist 3000-10000 out of 100000 cases of non-Hodgkin lymphoma in Asia and South America and less than 1000 in 10000 patient in western countries.<ref name="AozasaOhsawa1989">{{cite journal|last1=Aozasa|first1=Katsuyuki|last2=Ohsawa|first2=Masahiko|last3=Tajima|first3=Kazuo|last4=Sasaki|first4=Ryoji|last5=Maeda|first5=Hajime|last6=Matsunaga|first6=Torn|last7=Friedmann|first7=I.|title=Nation-wide study of lethal mid-line granuloma in Japan: Frequencies of Wegener's granulomatosis, polymorphic reticulosis, malignant lymphoma and other related conditions|journal=International Journal of Cancer|volume=44|issue=1|year=1989|pages=63–66|issn=00207136|doi=10.1002/ijc.2910440112}}</ref> | ||
*It is estimated the incidence of NNKTL is higher in Asia by 10-folds. | *It is estimated the incidence of NNKTL is higher in Asia by 10-folds. | ||
* | * | ||
Revision as of 20:46, 23 August 2019
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ramyar Ghandriz MD[2] Sowminya Arikapudi, M.B,B.S. [3]
Overview
Epidemiology and Demographics
Mortality rate
- NK cell lymphoma shows a poor prognosis because of rapid local progression and distant metastasis.
Age
- The median age of onset is approximately 50 years and it is common in elderly.[1]
- Extranodal NK/T-cell lymphoma is a rare disease in children and often it is associated with mosquito-bite hypersensetivity or other EBV-associated disease.[2]
Race
- Natural Killer (NK) cell lymphoma is a rare disease. NK/T cell lymphoma, nasal type (NKTCL) and aggressive NK-cell leukemia (ANKCL) have a higher incidence in Asia, Central, and South America.
- Nk cell lymphoma is usually associated with Epstein-Barr virus infection.
Gender
- Extranodal NK/T-cell lymphoma shows male preponderance.
Region
- NK T cell lymphoma, nasal type (NNKTL) consist 3000-10000 out of 100000 cases of non-Hodgkin lymphoma in Asia and South America and less than 1000 in 10000 patient in western countries.[3]
- It is estimated the incidence of NNKTL is higher in Asia by 10-folds.
References
- ↑ Ko, Y H; Cho, E-Y; Kim, J-E; Lee, S-S; Huh, J-R; Chang, H-K; Yang, W-I; Kim, C-W; Kim, S-W; Ree, H J (2004). "NK and NK-like T-cell lymphoma in extranasal sites: a comparative clinicopathological study according to site and EBV status". Histopathology. 44 (5): 480–489. doi:10.1111/j.1365-2559.2004.01867.x. ISSN 0309-0167.
- ↑ Ng, Siok-Bian; Khoury, Joseph D. (2009). "Epstein-Barr Virus in Lymphoproliferative Processes". Advances in Anatomic Pathology. 16 (1): 40–55. doi:10.1097/PAP.0b013e3181916029. ISSN 1072-4109.
- ↑ Aozasa, Katsuyuki; Ohsawa, Masahiko; Tajima, Kazuo; Sasaki, Ryoji; Maeda, Hajime; Matsunaga, Torn; Friedmann, I. (1989). "Nation-wide study of lethal mid-line granuloma in Japan: Frequencies of Wegener's granulomatosis, polymorphic reticulosis, malignant lymphoma and other related conditions". International Journal of Cancer. 44 (1): 63–66. doi:10.1002/ijc.2910440112. ISSN 0020-7136.