Germ cell tumor differential diagnosis: Difference between revisions
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Hudakarman (talk | contribs) Differential diagnosis |
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*Cytoplasmic membrane immunoreactivity for placental alkaline phosphatase and CD117, with usual negativity for AE1/AE3 cytokeratins, is helpful in the diagnosis of germinoma. *The recently described marker, OCT3/4, a nuclear transcription factor, is especially helpful in the differential of germinoma and embryonal carcinoma with other neoplasms. | *Cytoplasmic membrane immunoreactivity for placental alkaline phosphatase and CD117, with usual negativity for AE1/AE3 cytokeratins, is helpful in the diagnosis of germinoma. | ||
*The recently described marker, OCT3/4, a nuclear transcription factor, is especially helpful in the differential of germinoma and embryonal carcinoma with other neoplasms. | |||
*Yolk sac tumor continues to be confused occasionally with clear cell carcinoma of the ovary. | *Yolk sac tumor continues to be confused occasionally with clear cell carcinoma of the ovary. | ||
Revision as of 14:12, 9 September 2019
- Cytoplasmic membrane immunoreactivity for placental alkaline phosphatase and CD117, with usual negativity for AE1/AE3 cytokeratins, is helpful in the diagnosis of germinoma.
- The recently described marker, OCT3/4, a nuclear transcription factor, is especially helpful in the differential of germinoma and embryonal carcinoma with other neoplasms.
- Yolk sac tumor continues to be confused occasionally with clear cell carcinoma of the ovary.