Extranodal NK-T-cell lymphoma epidemiology and demographics: Difference between revisions
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=== Mortality rate === | === Mortality rate === | ||
* NK cell lymphoma shows a poor [[prognosis]] because of rapid local progression and distant metastasis. | * NK cell lymphoma shows a poor [[prognosis]] because of rapid local progression and distant [[Metastasis - brain|metastasis]]<ref name="KoCho2004">{{cite journal|last1=Ko|first1=Y H|last2=Cho|first2=E-Y|last3=Kim|first3=J-E|last4=Lee|first4=S-S|last5=Huh|first5=J-R|last6=Chang|first6=H-K|last7=Yang|first7=W-I|last8=Kim|first8=C-W|last9=Kim|first9=S-W|last10=Ree|first10=H J|title=NK and NK-like T-cell lymphoma in extranasal sites: a comparative clinicopathological study according to site and EBV status|journal=Histopathology|volume=44|issue=5|year=2004|pages=480–489|issn=0309-0167|doi=10.1111/j.1365-2559.2004.01867.x}}</ref>. | ||
=== Age === | === Age === | ||
* The median age of onset is approximately 50 years and it is common in elderly. | * The [[median]] age of onset is approximately 50 years and it is common in elderly<ref name="TakahashiAsano2008">{{cite journal|last1=Takahashi|first1=E|last2=Asano|first2=N|last3=Li|first3=C|last4=Tanaka|first4=T|last5=Shimada|first5=K|last6=Shimada|first6=S|last7=Yoshino|first7=T|last8=Kojima|first8=M|last9=Hara|first9=K|last10=Eimoto|first10=T|last11=Nakamura|first11=S|title=Nodal T/NK-cell lymphoma of nasal type: a clinicopathological study of six cases|journal=Histopathology|volume=52|issue=5|year=2008|pages=585–596|issn=0309-0167|doi=10.1111/j.1365-2559.2008.02997.x}}</ref>. | ||
* Extranodal NK/T-cell lymphoma is a rare disease in children and often it is associated with mosquito-bite | *[[Extranodal NK-T-cell lymphoma|Extranodal NK/T-cell lymphoma]] is a rare disease in children and often it is associated with mosquito-bite [[hypersensitivity]] or other [[Epstein Barr virus|EBV]]-associated disease. | ||
=== Race === | === Race === | ||
* Natural Killer (NK) cell lymphoma is a rare disease. NK/T cell lymphoma, nasal type (NKTCL) and aggressive NK-cell leukemia (ANKCL) have a higher incidence in Asia, Central, and South America. | *[[Natural killer cell|Natural Killer (NK) cell]] lymphoma is a rare disease. NK/T cell lymphoma, nasal type (NKTCL) and aggressive NK-cell leukemia (ANKCL) have a higher incidence in Asia, Central, and South America<ref name="KoCho20042">{{cite journal|last1=Ko|first1=Y H|last2=Cho|first2=E-Y|last3=Kim|first3=J-E|last4=Lee|first4=S-S|last5=Huh|first5=J-R|last6=Chang|first6=H-K|last7=Yang|first7=W-I|last8=Kim|first8=C-W|last9=Kim|first9=S-W|last10=Ree|first10=H J|title=NK and NK-like T-cell lymphoma in extranasal sites: a comparative clinicopathological study according to site and EBV status|journal=Histopathology|volume=44|issue=5|year=2004|pages=480–489|issn=0309-0167|doi=10.1111/j.1365-2559.2004.01867.x}}</ref>. | ||
* Nk cell lymphoma is usually associated with Epstein-Barr virus infection. | * Nk cell lymphoma is usually associated with [[Epstein Barr virus|Epstein-Barr virus]] infection. | ||
=== Gender === | === Gender === | ||
* Extranodal NK/T-cell lymphoma shows male preponderance. | *[[Extranodal NK-T-cell lymphoma|Extranodal NK/T-cell lymphoma]] shows male preponderance<ref name="KoCho20043">{{cite journal|last1=Ko|first1=Y H|last2=Cho|first2=E-Y|last3=Kim|first3=J-E|last4=Lee|first4=S-S|last5=Huh|first5=J-R|last6=Chang|first6=H-K|last7=Yang|first7=W-I|last8=Kim|first8=C-W|last9=Kim|first9=S-W|last10=Ree|first10=H J|title=NK and NK-like T-cell lymphoma in extranasal sites: a comparative clinicopathological study according to site and EBV status|journal=Histopathology|volume=44|issue=5|year=2004|pages=480–489|issn=0309-0167|doi=10.1111/j.1365-2559.2004.01867.x}}</ref>. | ||
=== Region === | === Region === | ||
*NK T cell lymphoma, nasal type (NNKTL) consist 3000-10000 out of 100000 cases of non-Hodgkin lymphoma in Asia and South America and less than 1000 in 10000 patient in western countries. | *[[Extranodal NK-T-cell lymphoma|Extranodal NK T cell lymphoma]], nasal type (NNKTL) consist 3000-10000 out of 100000 cases of [[non-Hodgkin lymphoma]] in Asia and South America and less than 1000 in 10000 patient in western countries. | ||
*It is estimated the incidence of NNKTL is higher in Asia by 10-folds. | *It is estimated the incidence of NNKTL is higher in Asia by 10-folds. | ||
Revision as of 13:47, 1 October 2019
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ramyar Ghandriz MD[2] Sowminya Arikapudi, M.B,B.S. [3]
Overview
NK cell lymphoma shows a poor prognosis because of rapid local progression and distant metastasis.The median age of onset is approximately 50 years and it is common in elderly.Extranodal NK/T-cell lymphoma is a rare disease in children and often it is associated with mosquito-bite hypersensetivity or other EBV-associated disease.Natural Killer (NK) cell lymphoma is a rare disease. NK/T cell lymphoma, nasal type (NKTCL) and aggressive NK-cell leukemia (ANKCL) have a higher incidence in Asia, Central, and South America.NK T cell lymphoma, nasal type (NNKTL) consist 3000-10000 out of 100000 cases of non-Hodgkin lymphoma in Asia and South America and less than 1000 in 10000 patient in western countries
Epidemiology and Demographics
Mortality rate
- NK cell lymphoma shows a poor prognosis because of rapid local progression and distant metastasis[1].
Age
- The median age of onset is approximately 50 years and it is common in elderly[2].
- Extranodal NK/T-cell lymphoma is a rare disease in children and often it is associated with mosquito-bite hypersensitivity or other EBV-associated disease.
Race
- Natural Killer (NK) cell lymphoma is a rare disease. NK/T cell lymphoma, nasal type (NKTCL) and aggressive NK-cell leukemia (ANKCL) have a higher incidence in Asia, Central, and South America[3].
- Nk cell lymphoma is usually associated with Epstein-Barr virus infection.
Gender
- Extranodal NK/T-cell lymphoma shows male preponderance[4].
Region
- Extranodal NK T cell lymphoma, nasal type (NNKTL) consist 3000-10000 out of 100000 cases of non-Hodgkin lymphoma in Asia and South America and less than 1000 in 10000 patient in western countries.
- It is estimated the incidence of NNKTL is higher in Asia by 10-folds.
References
- ↑ Ko, Y H; Cho, E-Y; Kim, J-E; Lee, S-S; Huh, J-R; Chang, H-K; Yang, W-I; Kim, C-W; Kim, S-W; Ree, H J (2004). "NK and NK-like T-cell lymphoma in extranasal sites: a comparative clinicopathological study according to site and EBV status". Histopathology. 44 (5): 480–489. doi:10.1111/j.1365-2559.2004.01867.x. ISSN 0309-0167.
- ↑ Takahashi, E; Asano, N; Li, C; Tanaka, T; Shimada, K; Shimada, S; Yoshino, T; Kojima, M; Hara, K; Eimoto, T; Nakamura, S (2008). "Nodal T/NK-cell lymphoma of nasal type: a clinicopathological study of six cases". Histopathology. 52 (5): 585–596. doi:10.1111/j.1365-2559.2008.02997.x. ISSN 0309-0167.
- ↑ Ko, Y H; Cho, E-Y; Kim, J-E; Lee, S-S; Huh, J-R; Chang, H-K; Yang, W-I; Kim, C-W; Kim, S-W; Ree, H J (2004). "NK and NK-like T-cell lymphoma in extranasal sites: a comparative clinicopathological study according to site and EBV status". Histopathology. 44 (5): 480–489. doi:10.1111/j.1365-2559.2004.01867.x. ISSN 0309-0167.
- ↑ Ko, Y H; Cho, E-Y; Kim, J-E; Lee, S-S; Huh, J-R; Chang, H-K; Yang, W-I; Kim, C-W; Kim, S-W; Ree, H J (2004). "NK and NK-like T-cell lymphoma in extranasal sites: a comparative clinicopathological study according to site and EBV status". Histopathology. 44 (5): 480–489. doi:10.1111/j.1365-2559.2004.01867.x. ISSN 0309-0167.