Zollinger-Ellison syndrome other diagnostic studies: Difference between revisions
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*Bulbar erosions and [[ulcerations]] | *Bulbar erosions and [[ulcerations]] | ||
*Post-bulbar [[Gastric erosion|erosions]] and [[ulcerations]] | *Post-bulbar [[Gastric erosion|erosions]] and [[ulcerations]] | ||
===Immunostaining=== | |||
*[[Immunostaining]] for [[chromogranin A]] and [[synaptophysin]] is an important feature for the diagnosis of [[neuroendocrine tumors]]<ref name="pmid28722872">{{cite journal |vauthors=Cingam S, Karanchi H |title= |journal= |volume= |issue= |pages= |year= |pmid=28722872 |doi= |url=}}</ref> | |||
*In order to differentiate from other [[Neuroendocrine tumor|neuroendocrine tumors]] [[gastrin]] [[immunostaining]] may be helpful in differentiation.<ref name="pmid28722872">{{cite journal |vauthors=Cingam S, Karanchi H |title= |journal= |volume= |issue= |pages= |year= |pmid=28722872 |doi= |url=}}</ref> | |||
*Diagnostic accuracy of imaging for localization of [[gastrinoma]]: <ref name="pmid24319020">{{cite journal |vauthors=Epelboym I, Mazeh H |title=Zollinger-Ellison syndrome: classical considerations and current controversies |journal=Oncologist |volume=19 |issue=1 |pages=44–50 |year=2014 |pmid=24319020 |pmc=3903066 |doi=10.1634/theoncologist.2013-0369 |url=}}</ref> <ref name="pmid12628075">{{cite journal |vauthors=Hung PD, Schubert ML, Mihas AA |title=Zollinger-Ellison Syndrome |journal=Curr Treat Options Gastroenterol |volume=6 |issue=2 |pages=163–170 |year=2003 |pmid=12628075 |doi= |url=}}</ref> | |||
==References== | ==References== | ||
{{reflist|2}} | {{reflist|2}} | ||
Latest revision as of 16:28, 19 September 2019
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Mohamad Alkateb, MBBCh [2]
Overview
Other diagnostic studies for Zollinger-Ellison syndrome include upper endoscopy, which demonstrates erosive esophagitis, thickened gastric folds, and antral erosions.
Other Diagnostic Studies
Upper Endoscopy
Upper endoscopy may be helpful in the diagnosis of Zollinger-Ellison syndrome. Findings may include:[1]
- Esophageal erosions
- Thickened gastric folds
- Antral erosions
- Bulbar erosions and ulcerations
- Post-bulbar erosions and ulcerations
Immunostaining
- Immunostaining for chromogranin A and synaptophysin is an important feature for the diagnosis of neuroendocrine tumors[2]
- In order to differentiate from other neuroendocrine tumors gastrin immunostaining may be helpful in differentiation.[2]
- Diagnostic accuracy of imaging for localization of gastrinoma: [3] [4]
References
- ↑ Lee, Wan-Sik; Koh, Yang-Seok; Kim, Jung-Chul; Park, Chang-Hwan; Joo, Young-Eun; Kim, Hyun-Soo; Cho, Chol-Kyoon; Choi, Sung-Kyu; Rew, Jong-Sun; Kim, Sei-Jong (2005). "Abdominal gastrinoma". BMC Cancer. 5 (1): 85. doi:10.1186/1471-2407-5-85. ISSN 1471-2407.
- ↑ 2.0 2.1 Cingam S, Karanchi H. PMID 28722872. Missing or empty
|title=(help) - ↑ Epelboym I, Mazeh H (2014). "Zollinger-Ellison syndrome: classical considerations and current controversies". Oncologist. 19 (1): 44–50. doi:10.1634/theoncologist.2013-0369. PMC 3903066. PMID 24319020.
- ↑ Hung PD, Schubert ML, Mihas AA (2003). "Zollinger-Ellison Syndrome". Curr Treat Options Gastroenterol. 6 (2): 163–170. PMID 12628075.