Extranodal NK-T-cell lymphoma epidemiology and demographics: Difference between revisions
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=== Mortality rate === | === Mortality rate === | ||
* NK cell lymphoma shows a poor [[prognosis]] because of rapid local progression and distant [[Metastasis - brain|metastasis]]. | * NK cell lymphoma shows a poor [[prognosis]] because of rapid local progression and distant [[Metastasis - brain|metastasis]].<ref name="JaffeNicolae2013">{{cite journal|last1=Jaffe|first1=Elaine S|last2=Nicolae|first2=Alina|last3=Pittaluga|first3=Stefania|title=Peripheral T-cell and NK-cell lymphomas in the WHO classification: pearls and pitfalls|journal=Modern Pathology|volume=26|issue=S1|year=2013|pages=S71–S87|issn=0893-3952|doi=10.1038/modpathol.2012.181}}</ref> | ||
=== Age === | === Age === | ||
* The [[median]] age of onset is approximately 50 years and it is common in elderly | * The [[median]] age of onset is approximately 50 years and it is common in elderly. | ||
*[[Extranodal NK-T-cell lymphoma|Extranodal NK/T-cell lymphoma]] is a rare disease in children and often it is associated with mosquito-bite [[hypersensitivity]] or other [[Epstein Barr virus|EBV]]-associated disease. | *[[Extranodal NK-T-cell lymphoma|Extranodal NK/T-cell lymphoma]] is a rare disease in children and often it is associated with mosquito-bite [[hypersensitivity]] or other [[Epstein Barr virus|EBV]]-associated disease. | ||
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ramyar Ghandriz MD[2] Sowminya Arikapudi, M.B,B.S. [3]
Overview
NK cell lymphoma shows a poor prognosis because of rapid local progression and distant metastasis.The median age of onset is approximately 50 years and it is common in elderly. extranodal NK/T-cell lymphoma is a rare disease in children and often it is associated with mosquito-bite hypersensitivity or other EBV-associated disease.Natural Killer (NK) cell lymphoma is a rare disease. extranodal NK/T cell lymphoma, nasal type (NKTCL) and aggressive NK-cell leukemia (ANKCL) have a higher incidence in Asia, Central, and South America.NK T cell lymphoma, nasal type (NNKTL) consist 3000-10000 out of 100000 cases of non-Hodgkin lymphoma in Asia and South America and less than 1000 in 10000 patient in western countries
Epidemiology and Demographics
Mortality rate
- NK cell lymphoma shows a poor prognosis because of rapid local progression and distant metastasis.[1]
Age
- The median age of onset is approximately 50 years and it is common in elderly.
- Extranodal NK/T-cell lymphoma is a rare disease in children and often it is associated with mosquito-bite hypersensitivity or other EBV-associated disease.
Race
- Natural Killer (NK) cell lymphoma is a rare disease. NK/T cell lymphoma, nasal type (NKTCL) and aggressive NK-cell leukemia (ANKCL) have a higher incidence in Asia, Central, and South America.
- Nk cell lymphoma is usually associated with Epstein-Barr virus infection.
Gender
- Extranodal NK/T-cell lymphoma shows male preponderance.
Region
- Extranodal NK T cell lymphoma, nasal type (NNKTL) consist 3000-10000 out of 100000 cases of non-Hodgkin lymphoma in Asia and South America and less than 1000 in 10000 patient in western countries.
- It is estimated the incidence of NNKTL is higher in Asia by 10-folds.
References
- ↑ Jaffe, Elaine S; Nicolae, Alina; Pittaluga, Stefania (2013). "Peripheral T-cell and NK-cell lymphomas in the WHO classification: pearls and pitfalls". Modern Pathology. 26 (S1): S71–S87. doi:10.1038/modpathol.2012.181. ISSN 0893-3952.