Osteosarcoma x ray: Difference between revisions
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*[[Medullary]] and [[cortical bone]] destruction. | *[[Medullary]] and [[cortical bone]] destruction. | ||
*Wide zone of transition, permeative or moth-eaten appearance. | *Wide zone of [[transition]], permeative or moth-eaten appearance. | ||
*Aggressive [[periosteal reaction]] characterized by: | *Aggressive [[periosteal reaction]] characterized by: | ||
:*Sunburst appearance | :*Sunburst appearance | ||
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*Typically seen as an expansile lytic metaphyseal bony lesion. | *Typically seen as an expansile lytic metaphyseal bony lesion. | ||
*Geographic bony destruction with wide zone of transition tends to be more common than permeative bony destruction. | *Geographic bony destruction with wide zone of transition tends to be more common than permeative bony destruction. | ||
*Less osteoid matrix compared | *Less osteoid matrix compared to conventional type. | ||
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*Because the [[fibrous dysplasia]] and central low-grade osteosarcoma are so similar histologically, the radiographic features are an extremely important part of the diagnosis. | *Because the [[fibrous dysplasia]] and central low-grade osteosarcoma are so similar histologically, the radiographic features are an extremely important part of the diagnosis. | ||
*Radiographic features of low grade osteosarcomas are variable. | *Radiographic features of low-grade osteosarcomas are variable. | ||
*Most common pattern is as a large intracompartmental expansile lytic fibro-osseous lesion with coarsely thick or thin incomplete trabeculations. Another less common pattern is as a | *Most common pattern is as a large intracompartmental expansile lytic fibro-osseous lesion with coarsely thick or thin incomplete trabeculations. Another less common pattern is as a se sclerotic lesion. | ||
*Cortical erosion and soft tissue extension is also a common feature. | *Cortical erosion and soft tissue extension is also a common feature. | ||
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:Extra skeletal osteosarcoma | :Extra skeletal osteosarcoma | ||
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*Soft tissue density with variable amount of calcification which represents osteoid matrix formation, and is seen in approximately 50% of cases. | *Soft tissue density with a variable amount of calcification which represents osteoid matrix formation, and is seen in approximately 50% of cases. | ||
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Revision as of 13:23, 17 October 2019
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mohammadmain Rezazadehsaatlou[2].
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Osteosarcoma Microchapters |
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Diagnosis |
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Treatment |
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Case Studies |
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Osteosarcoma x ray On the Web |
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American Roentgen Ray Society Images of Osteosarcoma x ray |
Overview
On X-ray, osteosarcoma is characterized by medullary and cortical bone destruction, periosteal reaction, tumor matrix calcification, and soft tissue mass.
X Ray
Conventional radiography continues to play an important role in diagnosis of osteosarcoma. Typical appearances of conventional high grade osteosarcoma include:[1][2][3][4][5][6][7]
- Medullary and cortical bone destruction.
- Wide zone of transition, permeative or moth-eaten appearance.
- Aggressive periosteal reaction characterized by:
- Sunburst appearance
- Codman triangle
- Lamellated (onion skin) reaction: less frequently seen
- Soft-tissue mass.
- Tumor matrix ossification/calcification.
- Variable: reflects a combination of the amount of tumor bone production, calcified matrix, and osteoid.
- Ill-defined fluffy or cloud-like cf. to the rings and arcs of chondroid lesions.
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- The following table illustrates the findings on x-ray for the subtypes of osteosarcoma:[1]
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References
- ↑ 1.0 1.1 Osteosarcoma. Dr Amir Rezaee ◉ and Dr Frank Gaillard ◉ et al. Radiopaedia.org 2015. http://radiopaedia.org/articles/osteosarcoma
- ↑ Gürtler KF, Riebel T, Beron G, Heller M, Euler A (April 1984). "[Comparison of x-ray plain films, x-ray tomograms and computed tomograms in lung nodules in children and adolescents]". Rofo (in German). 140 (4): 416–20. doi:10.1055/s-2008-1052998. PMID 6425164.
- ↑ Riebel T, Knop J, Winkler K, Delling G (October 1986). "[Comparative x-ray and nuclear medical studies of osteosarcomas to evaluate the effectiveness of preoperative chemotherapy]". Rofo (in German). 145 (4): 365–72. doi:10.1055/s-2008-1048952. PMID 3022331.
- ↑ Dinkel E, Uhl H, Roeren T (April 1985). "[Lung metastases--limitations and possibilities of radiologic diagnosis]". Radiologe (in German). 25 (4): 158–65. PMID 3889998.
- ↑ Kesselring FO, Penn W (1982). "Radiological aspects of 'classic' primary osteosarcoma: value of some radiological investigations: A review". Diagn Imaging. 51 (2): 78–92. PMID 7042255.
- ↑ Kubo T, Furuta T, Johan MP, Adachi N, Ochi M (September 2016). "Percent slope analysis of dynamic magnetic resonance imaging for assessment of chemotherapy response of osteosarcoma or Ewing sarcoma: systematic review and meta-analysis". Skeletal Radiol. 45 (9): 1235–42. doi:10.1007/s00256-016-2410-y. PMID 27229874.
- ↑ Rothermundt C, Seddon BM, Dileo P, Strauss SJ, Coleman J, Briggs TW, Haile SR, Whelan JS (May 2016). "Follow-up practices for high-grade extremity Osteosarcoma". BMC Cancer. 16: 301. doi:10.1186/s12885-016-2333-y. PMC 4859955. PMID 27154292.