Lipoma overview: Difference between revisions
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==Causes== | ==Causes== | ||
There is no established [[cause]] for lipoma. However, [[trauma]] and some [[genetic]] abnormalities have been associated with its development. | |||
==Differentiating Lipoma other Diseases== | ==Differentiating Lipoma other Diseases== | ||
Revision as of 18:15, 21 November 2019
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
A lipoma is a common, benign tumor composed of fatty tissue.
Historical Perspective
In 1914, Dr. Gery and colleagues first described Hibernoma, tumor of brown fat tissue.
Classification
Lipoma may be classified into different subtypes depending on the classification system. They may be classified according to the anatomical location, the related tissues or other characteristics.
Pathophysiology
Lipoma is formed from mature adipocyte cells and is histologically indistinguishable from fat tissue. Recent studies have observed cytogenetic abnormalities in 50-60% of lipomas, suggesting its role in the lipoma pathogenesis. Rearrangements of chromosome 12 are the most commonly cytogenetic abnormality. In a cross-sectional appearance, the lipoma is pale yellow to orange and has a uniform greasy surface with a lobular pattern. The subcutaneous lipoma is usually encapsulated and has a distinct lobulated pattern.
Causes
There is no established cause for lipoma. However, trauma and some genetic abnormalities have been associated with its development.