Familial amyloidosis MRI: Difference between revisions
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==Overview== | ==Overview== | ||
MRI may be helpful in the diagnosis of familial amyloidosis. Findings on liver MRI suggestive of familial amyloidosis include [[liver enlargement]] with [[heterogeneous]] decreased attenuation, asymmetric and triangular [[hepatomegaly]] with the apex at the [[falciform ligament]], and [[Parenchyma|parenchymal]] [[calcification]]. Findings on [[Kidney|renal]] MRI suggestive of familial amyloidosis include [[kidney]] enlargement with [[heterogeneous]] decreased attenuation, and [[Parenchyma|parenchymal]] [[calcification]]. Findings on [[cardiac]] MRI suggestive of familial amyloidosis include [[heart enlargement]] with [[heterogeneous]] decreased attenuation, [[cardiac]] [[calcification]], and [[pericardial effusion]]. | MRI may be helpful in the diagnosis of familial amyloidosis. Findings on liver MRI suggestive of familial amyloidosis include [[liver enlargement]] with [[heterogeneous]] decreased attenuation, asymmetric and triangular [[hepatomegaly]] with the apex at the [[falciform ligament]], and [[Parenchyma|parenchymal]] [[calcification]]. Findings on [[Kidney|renal]] MRI suggestive of familial amyloidosis include hypodense [[Lesion|lesions]] on T2, [[kidney]] enlargement with [[heterogeneous]] decreased attenuation, and [[Parenchyma|parenchymal]] [[calcification]]. Findings on [[cardiac]] MRI suggestive of familial amyloidosis include [[heart enlargement]] with [[heterogeneous]] decreased attenuation, [[cardiac]] [[calcification]], and [[pericardial effusion]]. | ||
==MRI== | ==MRI== | ||
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In [[renal]] amyloidosis the [[MRI]] findings may include: | In [[renal]] amyloidosis the [[MRI]] findings may include: | ||
*Hypodense [[Lesion|lesions]] on T2 | |||
*[[Kidney]] enlargement with heterogeneous decreased attenuation | *[[Kidney]] enlargement with heterogeneous decreased attenuation | ||
*[[Parenchyma]] [[calcification]] (rare) | *[[Parenchyma]] [[calcification]] (rare) | ||
Revision as of 20:13, 25 November 2019
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Familial amyloidosis Microchapters |
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Diagnosis |
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Treatment |
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Case Studies |
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Familial amyloidosis MRI On the Web |
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American Roentgen Ray Society Images of Familial amyloidosis MRI |
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Risk calculators and risk factors for Familial amyloidosis MRI |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:
Overview
MRI may be helpful in the diagnosis of familial amyloidosis. Findings on liver MRI suggestive of familial amyloidosis include liver enlargement with heterogeneous decreased attenuation, asymmetric and triangular hepatomegaly with the apex at the falciform ligament, and parenchymal calcification. Findings on renal MRI suggestive of familial amyloidosis include hypodense lesions on T2, kidney enlargement with heterogeneous decreased attenuation, and parenchymal calcification. Findings on cardiac MRI suggestive of familial amyloidosis include heart enlargement with heterogeneous decreased attenuation, cardiac calcification, and pericardial effusion.
MRI
In cardiac amyloidosis the MRI findings may include[1]:
- Heart enlargement with heterogeneous decreased attenuation
- Cardiac calcifications
- Pericardial effusion (rare)
In hepatic amyloidosis the MRI scan findings may include:
- Liver enlargement with heterogeneous decreased attenuation
- Asymmetric and triangular hepatomegaly with the apex at the falciform ligament (due to mild atrophic change of the lateral border of both hepatic lobes)
- Parenchyma calcification (rare)
In renal amyloidosis the MRI findings may include:
- Hypodense lesions on T2
- Kidney enlargement with heterogeneous decreased attenuation
- Parenchyma calcification (rare)
In amyloidosis involving the peripheral nerves the MRI findings may include:
- Perineural enhancement
Images
References
- ↑ Falk RH, Quarta CC, Dorbala S (2014). "How to image cardiac amyloidosis". Circ Cardiovasc Imaging. 7 (3): 552–62. doi:10.1161/CIRCIMAGING.113.001396. PMC 4118308. PMID 24847009.
- ↑ Case courtesy of Dr David Cuevas, <a href="https://radiopaedia.org/">Radiopaedia.org</a>. From the case <a href="https://radiopaedia.org/cases/61600">rID: 61600</a>
- ↑ Case courtesy of Dr Rebecca Dumont Walter, <a href="https://radiopaedia.org/">Radiopaedia.org</a>. From the case <a href="https://radiopaedia.org/cases/42915">rID: 42915</a>