Dilated cardiomyopathy differential diagnosis

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Abdelrahman Ibrahim Abushouk, MD[2]

Overview

Dilated cardiomyopathy should be differentiated from other causes of cardiac dysfunction

Differentiating Beriberi from other Diseases

Dilated cardiomyopathy should be differentiated from other causes of cardiac dysfunction

Disorders	Etiology	Clinical Presentation	Laboratory Findings
Acute Coronary Syndrome	Atherosclerosis Coronary thrombosis Plaque rupture	Chest Pain Dyspnea Palpitations Nausea, vomiting, and sweating	Echocardiogram: ST segment and T wave changes, pathological Q waves. Elevated blood troponin levels (after 6 hours of attack onset) Elevated blood CK-MB levels
Acute Pericarditis	Idiopathic Viral infection Connective tissue diseases (e.g. SLE) Dressler's Syndrome (after MI) Familial Mediterranean fever	Sharp chest pain (that increases with breathing/cough, reduced with leaning forward) Pericardial friction rub Fever (for inflammatory causes)	Echocardiogram: Slight ST segment elevation in several leads & diffuse T wave inversion CBC: Increased WBCs count Modest increase in CK-MB Elevated CRP levels.
Amphetamine/Cocaine Cardiomyopathy
Arrhythmogenic right ventricular cardiomyopathy (ARVC/D)
Beriberi
Cardiac Temponade
Thyrotoxicosis
Hypertrophic Cardiomyopathy
Left ventricular noncompaction
Myocarditis
Restrictive Cardiomyopathy