A box gene transcriptions: Difference between revisions
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"A<sup>S/T</sup>, serine/threonine-rich subdomain within the A box".<ref name=Jin/> "A<sup>Q</sup>, glutamine-rich subdomain within the A box".<ref name=Jin/> | "A<sup>S/T</sup>, serine/threonine-rich subdomain within the A box".<ref name=Jin/> "A<sup>Q</sup>, glutamine-rich subdomain within the A box".<ref name=Jin/> | ||
"The human [Transforming growth factor b1] TGFB1 promoter region contains two binding sequences for [Activator protein-1] AP-1, designated AP-1 box A (TGACTCT) and box B (TGTCTCA), which mediate the upregulation of promoter activity via a PKC-dependent pathway after exposure of cells to a high-glucose environment (Refs 37, 38)."<ref name=Paratore>{{ cite journal | |||
|author=Amber Paratore Sanchez and Kumar Sharma | |||
|title=Transcription factors in the pathogenesis of diabetic nephropathy | |||
|journal=Expert Reviews in Molecular Medicine | |||
|date=July 2009 | |||
|volume=11 | |||
|issue= | |||
|pages=e13 | |||
|url=https://www.cambridge.org/core/journals/expert-reviews-in-molecular-medicine/article/transcription-factors-in-the-pathogenesis-of-diabetic-nephropathy/5459130CB955272C047982BE21FEE256 | |||
|arxiv= | |||
|bibcode= | |||
|doi=10.1017/S1462399409001057 | |||
|pmid= | |||
|accessdate=1 October 2018 }}</ref> | |||
==Acknowledgements== | ==Acknowledgements== | ||
Revision as of 05:39, 23 January 2020
The GC boxes are not apparently associated with the A box, B box, C box, and D box.[1]
"AS/T, serine/threonine-rich subdomain within the A box".[1] "AQ, glutamine-rich subdomain within the A box".[1]
"The human [Transforming growth factor b1] TGFB1 promoter region contains two binding sequences for [Activator protein-1] AP-1, designated AP-1 box A (TGACTCT) and box B (TGTCTCA), which mediate the upregulation of promoter activity via a PKC-dependent pathway after exposure of cells to a high-glucose environment (Refs 37, 38)."[2]
Acknowledgements
The content on this page was first contributed by: Henry A. Hoff.
Initial content for this page in some instances came from Wikiversity.
See also
References
- ↑ 1.0 1.1 1.2 Huajun Jin, Arthi Kanthasamy, Dilshan S. Harischandra, Naveen Kondru, Anamitra Ghosh, Nikhil Panicker, Vellareddy Anantharam, Ajay Rana, and Anumantha G. Kanthasamy (December 12, 2014). "Histone Hyperacetylation Up-regulates Protein Kinase C in Dopaminergic Neurons to Induce Cell Death RELEVANCE TO EPIGENETIC MECHANISMS OF NEURODEGENERATION IN PARKINSON DISEASE" (PDF). 289 (50): 34743–34767. doi:10.1074/jbc.M114.576702. Retrieved 10 April 2019.
- ↑ Amber Paratore Sanchez and Kumar Sharma (July 2009). "Transcription factors in the pathogenesis of diabetic nephropathy". Expert Reviews in Molecular Medicine. 11: e13. doi:10.1017/S1462399409001057. Retrieved 1 October 2018.