Cryptogenic stroke: Difference between revisions
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One cause is [[paradoxical embolism]] that may be treated with patent [[foramen ovale]] closure<ref name="pmid28902593">{{cite journal| author=Mas JL, Derumeaux G, Guillon B, Massardier E, Hosseini H, Mechtouff L et al.| title=Patent Foramen Ovale Closure or Anticoagulation vs. Antiplatelets after Stroke. | journal=N Engl J Med | year= 2017 | volume= 377 | issue= 11 | pages= 1011-1021 | pmid=28902593 | doi=10.1056/NEJMoa1705915 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=28902593 }} [https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=&cmd=prlinks&id=29335719 Review in: Ann Intern Med. 2018 Jan 16;168(2):JC7] </ref><ref name="pmid28902590">{{cite journal| author=Saver JL, Carroll JD, Thaler DE, Smalling RW, MacDonald LA, Marks DS et al.| title=Long-Term Outcomes of Patent Foramen Ovale Closure or Medical Therapy after Stroke. | journal=N Engl J Med | year= 2017 | volume= 377 | issue= 11 | pages= 1022-1032 | pmid=28902590 | doi=10.1056/NEJMoa1610057 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=28902590 }} </ref>. | One cause is [[paradoxical embolism]] that may be treated with patent [[foramen ovale]] closure<ref name="pmid28902593">{{cite journal| author=Mas JL, Derumeaux G, Guillon B, Massardier E, Hosseini H, Mechtouff L et al.| title=Patent Foramen Ovale Closure or Anticoagulation vs. Antiplatelets after Stroke. | journal=N Engl J Med | year= 2017 | volume= 377 | issue= 11 | pages= 1011-1021 | pmid=28902593 | doi=10.1056/NEJMoa1705915 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=28902593 }} [https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=&cmd=prlinks&id=29335719 Review in: Ann Intern Med. 2018 Jan 16;168(2):JC7] </ref><ref name="pmid28902590">{{cite journal| author=Saver JL, Carroll JD, Thaler DE, Smalling RW, MacDonald LA, Marks DS et al.| title=Long-Term Outcomes of Patent Foramen Ovale Closure or Medical Therapy after Stroke. | journal=N Engl J Med | year= 2017 | volume= 377 | issue= 11 | pages= 1022-1032 | pmid=28902590 | doi=10.1056/NEJMoa1610057 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=28902590 }} </ref>. | ||
One cause is [[atrial fibrillation]] which may be detected by prolonged, implantable recorders such as the LINQ<ref name="pmid24963567">{{cite journal| author=Sanna T, Diener HC, Passman RS, Di Lazzaro V, Bernstein RA, Morillo CA et al.| title=Cryptogenic stroke and underlying atrial fibrillation. | journal=N Engl J Med | year= 2014 | volume= 370 | issue= 26 | pages= 2478-86 | pmid=24963567 | doi=10.1056/NEJMoa1313600 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24963567 }} </ref><ref name="pmid31944175">{{cite journal| author=Edwards SJ, Wakefield V, Jhita T, Kew K, Cain P, Marceniuk G| title=Implantable cardiac monitors to detect atrial fibrillation after cryptogenic stroke: a systematic review and economic evaluation. | journal=Health Technol Assess | year= 2020 | volume= 24 | issue= 5 | pages= 1-184 | pmid=31944175 | doi=10.3310/hta24050 | pmc=6983910 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=31944175 }} </ref>. | One cause is [[atrial fibrillation]] which may be detected by prolonged event monitors<ref name="pmid24963566">{{cite journal| author=Gladstone DJ, Spring M, Dorian P, Panzov V, Thorpe KE, Hall J et al.| title=Atrial fibrillation in patients with cryptogenic stroke. | journal=N Engl J Med | year= 2014 | volume= 370 | issue= 26 | pages= 2467-77 | pmid=24963566 | doi=10.1056/NEJMoa1311376 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24963566 }} [https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=&cmd=prlinks&id=25185267 Review in: Evid Based Med. 2014 Dec;19(6):235] [https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=&cmd=prlinks&id=25402535 Review in: Ann Intern Med. 2014 Nov 18;161(10):JC2] [https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=&cmd=prlinks&id=25402536 Review in: Ann Intern Med. 2014 Nov 18;161(10):JC3] </ref> or prolonged, implantable recorders such as the LINQ<ref name="pmid24963567">{{cite journal| author=Sanna T, Diener HC, Passman RS, Di Lazzaro V, Bernstein RA, Morillo CA et al.| title=Cryptogenic stroke and underlying atrial fibrillation. | journal=N Engl J Med | year= 2014 | volume= 370 | issue= 26 | pages= 2478-86 | pmid=24963567 | doi=10.1056/NEJMoa1313600 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24963567 }} </ref><ref name="pmid31944175">{{cite journal| author=Edwards SJ, Wakefield V, Jhita T, Kew K, Cain P, Marceniuk G| title=Implantable cardiac monitors to detect atrial fibrillation after cryptogenic stroke: a systematic review and economic evaluation. | journal=Health Technol Assess | year= 2020 | volume= 24 | issue= 5 | pages= 1-184 | pmid=31944175 | doi=10.3310/hta24050 | pmc=6983910 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=31944175 }} </ref>. | ||
For cryptogenic stroke on unknown source, anticoagulation may not help over aspirin<ref name="pmid31091372">{{cite journal| author=Diener HC, Sacco RL, Easton JD, Granger CB, Bernstein RA, Uchiyama S et al.| title=Dabigatran for Prevention of Stroke after Embolic Stroke of Undetermined Source. | journal=N Engl J Med | year= 2019 | volume= 380 | issue= 20 | pages= 1906-1917 | pmid=31091372 | doi=10.1056/NEJMoa1813959 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=31091372 }} </ref>. | For cryptogenic stroke on unknown source, anticoagulation may not help over aspirin<ref name="pmid31091372">{{cite journal| author=Diener HC, Sacco RL, Easton JD, Granger CB, Bernstein RA, Uchiyama S et al.| title=Dabigatran for Prevention of Stroke after Embolic Stroke of Undetermined Source. | journal=N Engl J Med | year= 2019 | volume= 380 | issue= 20 | pages= 1906-1917 | pmid=31091372 | doi=10.1056/NEJMoa1813959 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=31091372 }} </ref>. | ||
Revision as of 07:18, 1 February 2020
In neurology, Cryptogenic stroke is stroke of undetermined source.
One cause is paradoxical embolism that may be treated with patent foramen ovale closure[1][2].
One cause is atrial fibrillation which may be detected by prolonged event monitors[3] or prolonged, implantable recorders such as the LINQ[4][5].
For cryptogenic stroke on unknown source, anticoagulation may not help over aspirin[6].
See also
External links
References
- ↑ Mas JL, Derumeaux G, Guillon B, Massardier E, Hosseini H, Mechtouff L; et al. (2017). "Patent Foramen Ovale Closure or Anticoagulation vs. Antiplatelets after Stroke". N Engl J Med. 377 (11): 1011–1021. doi:10.1056/NEJMoa1705915. PMID 28902593. Review in: Ann Intern Med. 2018 Jan 16;168(2):JC7
- ↑ Saver JL, Carroll JD, Thaler DE, Smalling RW, MacDonald LA, Marks DS; et al. (2017). "Long-Term Outcomes of Patent Foramen Ovale Closure or Medical Therapy after Stroke". N Engl J Med. 377 (11): 1022–1032. doi:10.1056/NEJMoa1610057. PMID 28902590.
- ↑ Gladstone DJ, Spring M, Dorian P, Panzov V, Thorpe KE, Hall J; et al. (2014). "Atrial fibrillation in patients with cryptogenic stroke". N Engl J Med. 370 (26): 2467–77. doi:10.1056/NEJMoa1311376. PMID 24963566. Review in: Evid Based Med. 2014 Dec;19(6):235 Review in: Ann Intern Med. 2014 Nov 18;161(10):JC2 Review in: Ann Intern Med. 2014 Nov 18;161(10):JC3
- ↑ Sanna T, Diener HC, Passman RS, Di Lazzaro V, Bernstein RA, Morillo CA; et al. (2014). "Cryptogenic stroke and underlying atrial fibrillation". N Engl J Med. 370 (26): 2478–86. doi:10.1056/NEJMoa1313600. PMID 24963567.
- ↑ Edwards SJ, Wakefield V, Jhita T, Kew K, Cain P, Marceniuk G (2020). "Implantable cardiac monitors to detect atrial fibrillation after cryptogenic stroke: a systematic review and economic evaluation". Health Technol Assess. 24 (5): 1–184. doi:10.3310/hta24050. PMC 6983910 Check
|pmc=value (help). PMID 31944175. - ↑ Diener HC, Sacco RL, Easton JD, Granger CB, Bernstein RA, Uchiyama S; et al. (2019). "Dabigatran for Prevention of Stroke after Embolic Stroke of Undetermined Source". N Engl J Med. 380 (20): 1906–1917. doi:10.1056/NEJMoa1813959. PMID 31091372.